Abstract: A microfluidic apparatus includes a microfluidic chip for MicroOrganoSpheres (MOS) generation. A first channel is defined in a surface of the microfluidic chip and includes: a droplet generation portion including an inlet portion, a junction between the inlet portion and an emulsifying fluid channel, and a chamber downstream of the junction. A cross-sectional area of the chamber is larger than that of the inlet portion. The first channel includes a polymerization portion downstream of the droplet generation portion, the polymerization portion having a serpentine configuration. The apparatus includes a cartridge for MOS demulsification, including: a collection container; a substrate disposed on the collection container, and a membrane disposed between the collection container and the surface of the substrate. A second channel is defined in the surface of the substrate that faces the collection container and is fluidically connected to an output of the polymerization portion of the first channel.

Abstract: A microfluidic apparatus includes a microfluidic chip for MicroOrganoSpheres (MOS) generation. A first channel is defined in a surface of the microfluidic chip and includes: a droplet generation portion including an inlet portion, a junction between the inlet portion and an emulsifying fluid channel, and a chamber downstream of the junction. A cross-sectional area of the chamber is larger than that of the inlet portion. The first channel includes a polymerization portion downstream of the droplet generation portion, the polymerization portion having a serpentine configuration. The apparatus includes a cartridge for MOS demulsification, including: a collection container; a substrate disposed on the collection container, and a membrane disposed between the collection container and the surface of the substrate. A second channel is defined in the surface of the substrate that faces the collection container and is fluidically connected to an output of the polymerization portion of the first channel.

Abstract: An air refresh system (10) for use in a occupant compartment. The system (10) includes a pressurized container assembly (12) for storing a pressurized refresh fluid (14), one or more nozzles (20) for dispersing the pressurized refresh fluid (14) and one or more electronically activated valves (22) for controlling the flow of the pressurized refresh fluid (14) from the container assembly (12) to the nozzles (20). The system (10) also has a microprocessor-based controller (24) programed to: receive one ore more user input signals (28), process the one or more user input signals (28) to obtain one or more fluid control signals (34), and transmit the one or more fluid control signals (34) to the one or more electronically activated valves (22) to allow the pressurized refresh fluid (14) to flow from the container assembly (12) to the one or more nozzles (20), wherein the one or more nozzles (20) spray the pressurized refresh fluid (14) into the vehicle to refresh air in the vehicle.