Abstract: The present invention provides a device for delivering a predetermined volume of a substance, within at least one body cavity of a subject, comprising: a. a predefined volume for containing said predetermined volume of said at least one substance; b. a delivery end for placement in proximity to said body cavity; said delivery end comprises at least one orifice of diameter D [mm]; c. a valve mechanically connectable to said container, characterized by at least two configurations: (i) an active configuration in which said valve enables delivery of predetermined volume Vsub [ml] of said substance; and, (ii) an inactive configuration, in which said valve prevents delivery of said predetermined volume Vsub [ml] of said substance from said container to said body cavity; d. a fluid tight chamber configured to contain predetermined volume Vgas [ml] of pressurized gas at a predetermined pressure, Pgas [barg].

Abstract: A device for delivering a predetermined amount of a substance within at least one body cavity of a subject, where the predetermined amount is at an effective amount for treatment of obesity or binge eating disorder. The device comprises: (a) A volume to contain the predetermined amount of the substance. (b) A delivery end placeable in proximity to the body cavity. The delivery end is in fluid communication with the volume and comprises at least one orifice. (c) A valve mechanically connected to the volume, with at least two configurations: (i) an active configuration configured to deliver the predetermined amount of the substance; and, (ii) an inactive configuration, in which the valve prevents delivery of the predetermined amount of the substance. (d) A fluid tight chamber configured to contain a predetermined volume of pressurized gas at a predetermined pressure.

Abstract: The present invention provides a method for delivering a substance to the nasal cavity of a subject in which drawing air from a mouthpiece triggers release of a substance to a subject's nasal cavities. The device comprises a container for containing the substance in fluid communication with a nosepiece, a valve with an active configuration and an inactive configuration, and a trigger mechanism to reconfigure the valve from its inactive configuration to its active configuration and vice versa. Drawing air from the mouthpiece, e.g., when the subject takes in air by mouth, activates the trigger mechanism, thereby reconfiguring the valve from its inactive configuration to its active configuration for a predetermined period of time and delivering the substance from the device to a nasal cavity of the subject.

Abstract: The present invention provides a method for delivering a substance to the nasal cavity of a subject in which drawing air from a mouthpiece triggers release of a substance to a subject's nasal cavities. The device comprises a container for containing the substance in fluid communication with a nosepiece, a valve with an active configuration and an inactive configuration, and a trigger mechanism to reconfigure the valve from its inactive configuration to its active configuration and vice versa. Drawing air from the mouthpiece, e.g., when the subject takes in air by mouth, activates the trigger mechanism, thereby reconfiguring the valve from its inactive configuration to its active configuration for a predetermined period of time and delivering the substance from the device to a nasal cavity of the subject.

Abstract: The present invention provides a method for delivering a substance to the nasal cavity of a subject in which drawing air from a mouthpiece triggers release of a substance to a subject's nasal cavities. The device comprises a container for containing the substance in fluid communication with a nosepiece, a valve with an active configuration and an inactive configuration, and a trigger mechanism to reconfigure the valve from its inactive configuration to its active configuration and vice versa. Drawing air from the mouthpiece, e.g., when the subject takes in air by mouth, activates the trigger mechanism, thereby reconfiguring the valve from its inactive configuration to its active configuration for a predetermined period of time and delivering the substance from the device to a nasal cavity of the subject.

Abstract: The present invention provides an air-intake device for delivering a substance to the nasal cavity of a subject which comprises: a container for containing the substance; a nosepiece and a mouthpiece extending from the device, for placement in proximity to the nose and mouth of the subject, respectively; a valve mechanically connectable to the container, with an active configuration and an inactive configuration; and, a trigger mechanism to reconfigure the valve from the active configuration to the inactive configuration, and vice versa. The trigger mechanism is activated by intaking air through the mouthpiece by the subject. Drawing air from the mouthpiece reconfigures the valve from its inactive configuration to its active configuration for a predetermined period of time and delivers the substance from the device to a nasal cavity of the subject.

Abstract: A device for delivering a predetermined volume a substance within a body cavity. The device includes: at least one predefined volume sized and shaped to contain a predetermined volume the substance; a delivery end in fluid communication with a container; and at least one valve mechanically connected to the container and configurable between an active configuration in which the valve enables delivery of a volume of the substance and an inactive configuration, in which the valve prevents delivery.

Abstract: The present invention provides a method for delivering a substance to the nasal cavity of a subject in which drawing air from a mouthpiece triggers release of a substance to a subject's nasal cavities. The device comprises a container for containing the substance in fluid communication with a nosepiece, a valve with an active configuration and an inactive configuration, and a trigger mechanism to reconfigure the valve from its inactive configuration to its active configuration and vice versa. Drawing air from the mouthpiece, e.g., when the subject takes in air by mouth, activates the trigger mechanism, thereby reconfiguring the valve from its inactive configuration to its active configuration for a predetermined period of time and delivering the substance from the device to a nasal cavity of the subject.

Abstract: A drinking actuated device for delivering a substance to the nasal cavity of a subject, comprising: a container for containing the substance; a nosepiece extending from the device for placement in proximity to the nose of a subject, with the nosepiece in fluid communication with the container; a valve mechanically connectable to the container, characterized by an active configuration and an inactive configuration; and a trigger mechanism adapted to reversibly reconfigure the valve from the active configuration to the inactive configuration. The mouthpiece is fluidly connectable to by means of a tubule to a fluid reservoir containing a fluid. Drawing liquid from the reservoir into the mouth via the mouthpiece reconfigures the valve from the inactive configuration to the active configuration for a predetermined period of time in response to the pressure gradient generated by the suction applied by the subject to the tubule.

Abstract: The present invention provides a two-step mechanism for delivering a flowable substance to the nasal passages, comprising: a. a nosepiece adapted to be in fluid connection with said nasal passages; b. at least one air-tight enclosure, comprising predetermined amount of compressed gas in the same; said compressed gas is pressurized to predetermined amount of pressure; c. a charging mechanism, fluidly connected with said air-tight enclosure, characterized by at least two configurations: a retracted position and an extended position; where, when said charging mechanism is transformed from said extended position to said retracted position, said charging mechanism is adapted to enable delivery of said pressurized and predetermined amount of compressed gas from at least one first predetermined position in said air-tight enclosure to at least one second predetermined position; d.

Abstract: The present invention provides a device for delivering a predetermined amount of at least one substance to a body orifice of a subject; comprising: a. a container for containing said at least one substance; b. a delivery end for placement in proximity to said orifice, said delivery end being in fluid communication with said container; c. a valve mechanically connectable to said container, characterized by at least two configurations: (i) an ACTIVE CONFIGURATION in which said valve enables delivery of predetermined amount of said substance from said container to said body orifice via said delivery end; and, (ii) an INACTIVE CONFIGURATION, in which said valve prevents delivery of said predetermined amount of said substance from said container to said body orifice; d. a trigger mechanism adapted to reconfigure said valve from said INACTIVE CONFIGURATION to said ACTIVE CONFIGURATION, and vice versa; e. a fluid tight chamber.

Abstract: It is one object of the present invention to provide an air-intake actuated device adapted for delivering a substance to a nasal cavity of a subject, comprising: a. a container for containing said substance; b. a nosepiece extending from said device for placement in proximity to a nose of said subject. c. a valve mechanically connectable to said container, characterized by an ACTIVE CONFIGURATION and an INACTIVE CONFIGURATION; and, d. a trigger mechanism adapted to reconfigure said valve from said ACTIVE CONFIGURATION to said INACTIVE CONFIGURATION, and vice versa; wherein said trigger mechanism is activated by means of said subject intaking air through said mouthpiece; further wherein said trigger mechanism is adapted to reconfigure said valve from said INACTIVE CONFIGURATION to said ACTIVE CONFIGURATION for a predetermined period of time in response to said subject intake of air.

Abstract: An infant mouth-nose mask for administering medicaments to infants, comprising: a. a mouth portion, defining a confined mouth volume, placed over the mouth of said infant characterized by having at least one perforation reversibly coupled to calming or feeding means such that said infant remains relaxed and soothed while sucking said calming or feeding means; said confined mouth volume is characterized by volume, Vmouth; and, b. a nose portion, defining a confined mouth volume, placed over the nose of said infant; said nose portion is adapted to be in fluid connection with a medicament delivery source (MDS); said confined nose volume is characterized by volume, Vnose; wherein said Vnose>>a*Vmouth such that the dead-space of said mask is not greater than 28 cc, and a is in the range of about 1.5 to about 2.

Abstract: An emergency escape breathing device comprises an oxygen bottle configured to contain compressed oxygen, an oxygen release regulator configured to release of the compressed oxygen at a constant rate during use of the emergency escape breathing device, the oxygen release regulator being substantially contained within the oxygen bottle.

Abstract: Respirator having a transparent bag for covering a head of a user and at least one filter for filtering air from outside the bag. The at least one filter is attached to the bag and located away from a line of sight of the user. A band attached to the bag is located around the top of the head.

Abstract: Breathing apparatuses for protecting users from inhaling contaminated air through their mouth and nose. One of the exemplary breathing apparatuses utilizes a filtering unit, whereas another exemplary breathing apparatus utilizes a air source in conjunction with a filtering unit. A nose plug prevents the contaminated air from entering the users' nose and a transparent bag prevents the contaminated air from entering the eyes, ears and noses of the users.