Abstract: The present invention relates to the classification of cancers, in particular prostate cancers, using samples from patients. In particular, the invention provides methods for identifying potentially aggressive prostate cancers to determine which cancers are or will become aggressive (and hence require treatment) and which will remain indolent (and will therefore not require treatment). The present invention is therefore useful to identify patients with a poor prognosis. The specific population of cancer identified by the present invention is referred to herein as DESNT cancer. The invention also provides biomarker panels useful in the diagnosis and prognosis of cancer.

Abstract: The present invention relates to the classification of cancers, in particular prostate cancers, using samples from patients. In particular, the invention provides methods for identifying potentially aggressive prostate cancers to determine which cancers are or will become aggressive (and hence require treatment) and which will remain indolent (and will therefore not require treatment). The present invention is therefore useful to identify patients with a poor prognosis. The specific population of cancer identified by the present invention is referred to herein as DESNT cancer. The invention also provides biomarker panels useful in the diagnosis and prognosis of cancer.

Abstract: The present invention relates to biomarkers and diagnostic profiles based on the expression status of particular genes for use in the diagnosis of prostate cancer, in particular the early detection of prostate cancer and prediction of disease progression and Gleason ?4 cancer. The present invention also provides methods of diagnosis and treatment of prostate cancer, and kits for the early detection of prostate cancer based on the expression status of the biomarkers in biological samples, in particular urine samples.

Abstract: The present invention relates to the classification of prostate cancers using samples from patients. Classification is achieved using a novel analysis method that uses less computing power than methods of the prior art. In particular, the invention provides new methods for classifying cancers to make a determination of risk of cancer progression (for example in early cancer), to identify patient populations that may be susceptible to particular treatments and to present opportunities (for example to provide tailored treatment regimens), or to identify patient populations that do not require treatment. The methods of the invention may include identifying potentially aggressive cancers to determine which cancers are or will become aggressive (and hence require treatment) and which will remain indolent (and will therefore not require treatment). The present invention is therefore useful to identify a patient's prognosis and identify those with good or poor prognoses.

Abstract: The present invention relates to the classification of cancers, in particular prostate cancers, using samples from patients. In particular, the invention provides methods for identifying potentially aggressive prostate cancers to determine which cancers are or will become aggressive (and hence require treatment) and which will remain indolent (and will therefore not require treatment). The present invention is therefore useful to identify patients with a poor prognosis. The specific population of cancer identified by the present invention is referred to herein as DESNT cancer. The invention also provides biomarker panels useful in the diagnosis and prognosis of cancer.