Abstract: A blood pressure sleeve includes a first sheet having a top side and a bottom side and a second sheet having a top surface and a bottom surface. The second sheet is attached to the first sheet and defines an inflatable portion, the first and second sheets each having a fluid impermeable surface. The inflatable portion includes an opening sized for receiving a port that interconnects the exterior of the sleeve with the interior of the inflatable portion and in which the first sheet includes a slotted portion opposite the port and aligned therewith to receive the port when the sleeve is wrapped about the limb of a patient, and in which at least a portion of the wrapped cuff is treated to reduce frictional effects.