Abstract: Provided herein are radiopharmaceutical compositions and uses thereof. The radiopharmaceutical compositions can comprise one or more stabilizing agents, an aqueous vehicle, and a conjugate that comprises a targeting ligand and a radionuclide bound to a metal chelator. The targeting ligand can be a small molecule compound or a peptide such as a monocyclic peptide. The targeting ligand can be configured to bind with a tumor target. The stabilizing agent can comprise a radiolysis stabilizer, a free metal chelator, and/or a pH stabilizer. Further provided herein are methods of preparing the radiopharmaceutical compositions and methods of treating cancer by administering the described radiopharmaceutical compositions.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: In some implementations, the invention may include the generation of a quantitative hardware performance model based on the obtained hardware specification via a computing platform. In addition, the invention may include obtaining a starting DNN model and DNN performance requirements for the optimized DNN model. The invention may include the generation of a DNN performance model based on the received starting DNN model and the received DNN performance requirements. Moreover, the invention may include the generation of an optimized DNN model through applying the quantitative hardware performance model and the DNN performance model to an optimization space of a plurality of DNN model instances.

Abstract: A computer-implemented technique is described herein for assisting a user in advancing a task objective. The technique uses a suggestion-generating system (SGS) to provide one or more suggestions to a user in response to at least a last-submitted query provided by the user. The SGS may correspond to a classification-type or generative-type neural network. The SGS uses a machine-trained model that is trained using a multi-task training framework based on plural groups of training examples, which, in turn, are produced using different respective example-generating methods. One such example-generating method constructs a training example from queries in a search session. It operates by identifying the task-related intent the queries, and then identifying at least one sequence of queries in the search session that exhibits a coherent task-related intent. A training example is constructed based on queries in such a sequence.

Abstract: A synthetic hydrogel is described, including hydrated mucin glycoproteins cross-linked with multi-arm thiol functional cross-linker, which can be prepared to model viscoelastic and micro-rheological properties of natural mucus. Such synthetic hydrogel can be prepared from a wide variety of mucin raw materials. Also described is a method of microrheologically characterizing mucus, by dispersing in the mucus muco-inert particles (MIP), irradiating the mucus containing MIP with polarized light, and measuring fluorescence polarization (FP) resulting from rotational diffusion of the MIP in the mucus in response to such irradiating, as a microrheological characteristic of the mucus. This method can be carried out using a plate reader equipped with a spectrofluorometer and polarized filter set, and therefore can be readily carried out in clinical settings without the necessity of specialized microrheological equipment.

Abstract: A piezoelectric harvesting system using repulsion force, according to one embodiment of the present invention, comprises: a piezoelectric body comprising a piezoelectric material; a fixed portion to at least one surface of which the piezoelectric body is adhered; a support portion for supporting one side of the fixed portion; and a repulsion force-providing portion for providing repulsion force to the fixed portion, so that the piezoelectric body generates electric energy when the fixed portion is deformed due to application of external force and then recovered. According to one embodiment of the present invention, additional shock is applied to the fixed portion to which the piezoelectric body is adhered when recovering after being deformed, thereby increasing the amount of electric energy generated due to the deformation of the piezoelectric body.

Abstract: Systems and methods are disclosed for processing information related to a terminal operating system. In one exemplary implantation, there is provided a method for providing information of terminal operating system management. The method may include processing information related to an input to manage the terminal operating system management. Other exemplary implementations may include processing to generate a result such that an output of a result of the managed terminal operating system management functionality is produced.

Abstract: Embodiments of the present disclosure are directed to a system comprising a processing unit executing an enumeration process over a high performance I/O network having endpoint locations that can be populated with endpoint devices. The system further comprises endpoint emulators to represent endpoint devices at endpoint locations unpopulated during the enumeration process. The system facilitates accessing certain endpoint devices later inserted (e.g., hot plugged) into the endpoint locations that were unpopulated during the enumeration process. The endpoint emulators can be implemented using various techniques, such as cards plugged into card slots coupled to the endpoint locations, or emulation software and/or firmware exposed to the processing unit. In an embodiment, the system is a test system for testing endpoint devices (e.g., PCIe SSDs), which test system can facilitate hot plugging of units under test in test slots that were unpopulated during the enumeration process.

Abstract: Systems and methods are disclosed associated with processing information involving terminal operating systems. According to one illustrative implementation, an exemplary method for processing information involving terminal operating system herein may include processing data in a TOS format associated with a TOS type, converting the data into a TOS agnostic format, and performing processing using the TOS agnostic data.

Abstract: Systems and methods are disclosed for processing information related to a terminal operating system. In one exemplary implantation, there is provided a method for providing information of terminal operating system management. The method may include processing information related to an input to manage the terminal operating system management. Other exemplary implementations may include processing to generate a result such that an output of a result of the managed terminal operating system management functionality is produced.

Abstract: Embodiments of the present disclosure are directed to a system comprising a processing unit executing an enumeration process over a high performance I/O network having endpoint locations that can be populated with endpoint devices. The system further comprises endpoint emulators to represent endpoint devices at endpoint locations unpopulated during the enumeration process. The system facilitates accessing certain endpoint devices later inserted (e.g., hot plugged) into the endpoint locations that were unpopulated during the enumeration process. The endpoint emulators can be implemented using various techniques, such as cards plugged into card slots coupled to the endpoint locations, or emulation software and/or firmware exposed to the processing unit. In an embodiment, the system is a test system for testing endpoint devices (e.g., PCIe SSDs), which test system can facilitate hot plugging of units under test in test slots that were unpopulated during the enumeration process.

Abstract: Systems and methods are disclosed associated with processing information involving terminal operating systems. According to one illustrative implementation, an exemplary method for processing information involving terminal operating system herein may include processing data in a TOS format associated with a TOS type, converting the data into a TOS agnostic format, and performing processing using the TOS agnostic data.

Abstract: A piezoelectric harvesting system using repulsion force, according to one embodiment of the present invention, comprises: a piezoelectric body comprising a piezoelectric material; a fixed portion to at least one surface of which the piezoelectric body is adhered; a support portion for supporting one side of the fixed portion; and a repulsion force-providing portion for providing repulsion force to the fixed portion, so that the piezoelectric body generates electric energy when the fixed portion is deformed due to application of external force and then recovered. According to one embodiment of the present invention, additional shock is applied to the fixed portion to which the piezoelectric body is adhered when recovering after being deformed, thereby increasing the amount of electric energy generated due to the deformation of the piezoelectric body.

Abstract: Systems and methods are disclosed for processing information related to appointment systems as well as associated terminal operating systems and other related systems. According to one illustrative implementation, an exemplary method for processing information involving appointment systems herein may include receiving/handling/processing data in a TOS format associated with a TOS type, converting the data into a TOS agnostic format, and performing processing using the TOS agnostic data. In another exemplary implementation, there is provided computer-implemented methods for processing information for appointment systems in conjunction with associated systems and operations. Systems and computer-implemented methods herein may include or involve processing information related to an appointment system and interrelationships with associated terminal operating systems, gate systems, and/or various TOS-agnostic features and functionality.

Abstract: Systems and methods are disclosed for processing information related to a terminal operating system. According to one illustrative implementation, an exemplary method for processing information involving terminal operating system herein may include processing data in a TOS format associated with a TOS type, converting the data into a TOS agnostic format, and performing processing using the TOS agnostic data. In another exemplary implementation, there is provided a method for providing information of terminal operating system management. The method may include processing information related to an input to manage the terminal operating system management. Other exemplary implementations may include processing to generate a result such that an output of a result of the managed terminal operating system management functionality is produced.