Patents by Inventor Daniel Spyker

Daniel Spyker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140221413
    Abstract: A method of treating postoperative pain in a patient undergoing a surgery is described. The method is based on preoperative administration of a buprenorphine-containing transdermal dosage form. The dosage form can be administered to the patient, for example, 1-4 days prior to surgery. Alternative embodiments of the invention include subsequent transdermal dosage forms to treat the postoperative pain.
    Type: Application
    Filed: January 7, 2014
    Publication date: August 7, 2014
    Applicant: PURDUE PHARMA L.P.
    Inventors: Bruce E. REIDENBERG, Daniel A. SPYKER
  • Patent number: 8637073
    Abstract: Dosage regimens of buprenorphine to treat withdrawal or abstinence syndrome in a drug dependent or opioid tolerant patient who is pregnant are described. The method includes treating withdrawal or abstinence syndrome of the patient by transdermal administration of an amount of buprenorphine effective to reduce withdrawal symptoms. For example, a first buprenorphine-containing transdermal dosage form can be administered for a first dosing period that is no more than about 5 days; a second buprenorphine-containing transdermal dosage form for a second dosing period that is no more than about 5 days, the second dosage form comprising the same or a greater dosage of buprenorphine than the first dosage form; and a third buprenorphine-containing transdermal dosage form for a third dosing period that is at least 2 days, the third dosage form comprising the same or a greater dosage of buprenorphine than the second dosage form.
    Type: Grant
    Filed: July 26, 2004
    Date of Patent: January 28, 2014
    Assignee: Purdue Pharma L.P.
    Inventors: Bruce E. Reidenberg, Daniel A. Spyker
  • Publication number: 20110002975
    Abstract: A method of treating postoperative pain in a patient undergoing a surgery is described. The method is based on preoperative administration of a buprenorphine-containing transdermal dosage form. The dosage form can be administered to the patient, for example, 1-4 days prior to surgery. Alternative embodiments of the invention include subsequent transdermal dosage forms to treat the postoperative pain.
    Type: Application
    Filed: September 13, 2010
    Publication date: January 6, 2011
    Applicant: PURDUE PHARMA L.P.
    Inventors: Bruce E. REIDENBERG, Daniel A. Spyker
  • Patent number: 7413748
    Abstract: A specific dosage regimen of buprenorphine achieves pain relief from painful episodes due to sickle cell disease. The dosage regimen comprises administering to a patient in need of pain relief from sickle cell disease at least one BTDS transdermal patch. Alternatively, the dosing regimen comprises administering to the patient (1) a first buprenorphine-containing transdermal dosage form for a first dosing period; (2) administering to the patient a second buprenorphine-containing transdermal dosage form for a second dosing period, where the second dosage form comprises the same dosage of buprenorphine as, or a greater dosage of buprenorphine than, the first dosage form; and (3) administering to the patient a third buprenorphine-containing transdermal dosage form for a third dosing period, where the third dosage form comprises a greater dosage of buprenorphine than the second dosage form.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: August 19, 2008
    Assignee: Purdue Pharma L.P.
    Inventors: Bruce E. Reidenberg, Daniel A. Spyker
  • Publication number: 20080026042
    Abstract: A method of treating postoperative pain in a patient undergoing a surgery id described. The method is based on preoperative administration of a buprenorphine-containing transdermal dosage form. The dosage form can be administered to the patient, for example, 1-4 days prior to surgery. Alternative embodiments of the invention include subsequent transdermal dosage forms to treat the postoperative pain.
    Type: Application
    Filed: July 26, 2004
    Publication date: January 31, 2008
    Applicant: Euro-Celtique S.A.
    Inventors: Bruce E. Reidenberg, Daniel A. Spyker
  • Patent number: 7270830
    Abstract: Dosage regimens of buprenorphine achieving rapid pain relief without increasing nausea, vomiting, or other adverse effects, are described. Also described are buprenorphine dosage regimens for treating chronic pain comprising administering to the patient (1) a first buprenorphine-containing transdermal dosage form for a first dosing period that is no more than about 5 days; (2) a second buprenorphine-containing transdermal dosage form for a second dosing period that is no more than 5 days, the second dosage form comprising the same dosage of buprenorphine as, or a greater dosage of buprenorphine than, the first dosage form; and (3) a third buprenorphine-containing transdermal dosage form for a third dosing period, the third dosage form comprising a greater dosage of buprenorphine than the second dosage form.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: September 18, 2007
    Assignee: Purdue Pharma L.P.
    Inventors: Bruce E. Reidenberg, Daniel A. Spyker
  • Publication number: 20060240085
    Abstract: Dosage regimens of buprenorphine to treat withdrawal or abstinence syndrome in a drug dependent or opioid tolerant patient who is pregnant are described. The method includes treating withdrawal or abstinence syndrome of the patient by transdermal administration of an amount of buprenorphine effective to reduce withdrawal symptoms. For example, a first buprenorphine-containing transdermal dosage form for a second dosing period that is no more than about 5 days, the second dosage form comprising the same or a greater dosage of buprenorphine than the first dosage form; and a third buprenorphine-containing transdermal dosage form for a third dosing period that is at least 2 days, the third dosage form comprising the same or a greater dosage of buprenorphine than the second dosage form.
    Type: Application
    Filed: July 26, 2004
    Publication date: October 26, 2006
    Applicant: Euro-Celtique S.A.
    Inventors: Bruce Reidenberg, Daniel Spyker
  • Publication number: 20040126416
    Abstract: Dosage regimens of buprenorphine achieving rapid pain relief without increasing nausea, vomiting, or other adverse effects, are described. Also described are buprenorphine dosage regimens for treating chronic pain comprising administering to the patient (1) a first buprenorphine-containing transdermal dosage form for a first dosing period that is no more than about 5 days; (2) a second buprenorphine-containing transdermal dosage form for a second dosing period that is no more than 5 days, the second dosage form comprising the same dosage of buprenorphine as, or a greater dosage of buprenorphine than, the first dosage form; and (3) a third buprenorphine-containing transdermal dosage form for a third dosing period, the third dosage form comprising a greater dosage of buprenorphine than the second dosage form.
    Type: Application
    Filed: December 15, 2003
    Publication date: July 1, 2004
    Applicant: Euro-Celtique S.A.
    Inventors: Bruce E. Reidenberg, Daniel A. Spyker
  • Publication number: 20040126417
    Abstract: A specific dosage regimen of buprenorphine achieves pain relief from painful episodes due to sickle cell disease. The dosage regimen comprises administering to a patient in need of pain relief from sickle cell disease at least one BTDS transdermal patch. Alternatively, the dosing regimen comprises administering to the patient (1) a first buprenorphine-containing transdermal dosage form for a first dosing period; (2) administering to the patient a second buprenorphine-containing transdermal dosage form for a second dosing period, where the second dosage form comprises the same dosage of buprenorphine as, or a greater dosage of buprenorphine than, the first dosage form; and (3) administering to the patient a third buprenorphine-containing transdermal dosage form for a third dosing period, where the third dosage form comprises a greater dosage of buprenorphine than the second dosage form.
    Type: Application
    Filed: December 15, 2003
    Publication date: July 1, 2004
    Applicant: Euro-Celtique S.A.
    Inventors: Bruce E. Reidenberg, Daniel A. Spyker