Abstract: A method may include obtaining a pretrained image encoder and a training sample comprising a training image and a training text string corresponding to the training image. The method may also include initializing a text encoder in an untrained state, determining, using the pretrained image encoder and based on the training image, a first latent representation of the training image, and determining, using the text encoder and based on the training text string, a second latent representation of the training text string. The method may further include determining a loss value based on the first latent representation and the second latent representation, updating, based on the loss value, one or more parameters of the text encoder while holding fixed parameters of the pretrained image encoder, and outputting the text encoder in a trained state.

Abstract: Embodiments of a heating appliance with control features such as knobs can provide tactile feedback to the user during knob operation. Tactile feedback through the knob, e.g., during rotation in one or more directions, can improve control precision. Beneficial control accuracy features, such as can be utilized during appliance operation and setting of parameters of the heating appliance. A user's desired setting, such as various cooking modes or an off position can therefore be input into the heating appliance with tactile control aspects. A user's desired setting can therefore be accurately set, including with the benefit of tactile control aspects.

Abstract: The present invention relates to designed ankyrin repeat domains having a reduced isoelectric point (pI) and/or having a reduced number of basic amino acid residues. The invention also provides such repeat domains linked to a drug moiety, for example a radionuclide or a cytotoxic agent. The invention furthermore provides methods for producing such repeat domains, as well as the use of such repeat domains in therapeutic and/or diagnostic methods. In addition, the invention provides recombinant proteins comprising such repeat domains, nucleic acids encoding such repeat domains or recombinant proteins, pharmaceutical compositions comprising such repeat domains, recombinant proteins nucleic acids, recombinant expression vectors and host cells, and the use of such proteins, nucleic acids or pharmaceutical compositions in methods for treating diseases, such as cancer.

Abstract: A door drive device for adjusting and/or locking a vehicle door relative to a vehicle body including an adjustment member, a drive element operatively coupled to the adjustment member such that the adjustment member is movable with respect to the drive element for moving the vehicle door, a sensor device for measuring a measuring quantity indicative of a movement of the vehicle door to provide a sensor signal, a brake device operatively connected to the drive element for braking a movement of the vehicle door, and a control device for controlling operation of the door drive device. The control device is configured to compute, from the sensor signal obtained from the sensor device, an acceleration value indicative of an acceleration of the vehicle door and evaluate the acceleration value to distinguish movement of the vehicle door caused by a gravity force from movement caused by a user action.

Abstract: A cooking appliance includes an oven body having an interior compartment and a door panel for accessing the interior compartment, wherein the interior compartment is sized to receive a food product; a removable heated tray positionable within the interior compartment, wherein the heated tray includes a top tray surface and a first heating source positioned below the top tray surface; and a second heating source positioned within the interior compartment.

Abstract: A stump grinding system that includes a vehicle and a stump grinder adapted to engage with the vehicle. The vehicle has a first end, a second end opposite to the first end, and a longitudinal axis defined therebetween. The stump grinder includes a chassis operably engaged with the vehicle at one of the first end and the second end. The stump grinder also includes a body operably engaged with the chassis and a grinder wheel operably engaged with the body and partially disposed outside of the body from the vehicle. The stump grinder also includes a drive assembly operably engaged with the grinder wheel and the body. The grinder wheel of the stump grinder is configured to rotate in a plane that is orthogonal to the longitudinal axis of the vehicle.

Abstract: The invention relates to a thin film evaporator (D) for producing a transfer mixture according to the direct dissolution method, having a feed (1), a housing (4) and an outlet (2), wherein the feed (1) introduces a starting material, made of cellulose, water and a functional fluid, into the housing (4), wherein an evaporator shaft (5) situated in the housing (4) rotatingly sweeps the starting material over the heated interior of the housing (4), wherein the product is heated and some of the water evaporates so as to result in the transfer mixture, which flows to the outlet (2) together with a supply stream, wherein the through-flow capacity of the outlet (2) is greater than the supply stream.

Abstract: Mixing kneader for processing a transfer mixture into a molding solution, according to the direct dissolution method, having a feed, a housing and a discharge, wherein the feed introduces a product consisting essentially of cellulose, water and a functional liquid into the housing, wherein a kneader shaft situated in the housing rotationally mixes and kneads the product and sweeps wipes it over heated inner surfaces of the mixing kneader, wherein reducing the amount of undissolved particles in the product and the size of the particles are reduced, and evaporating some of the water evaporates to produce form a molding solution, wherein the process volume of the mixing kneader is determined only by the requirements of a molding solution flow capacity.

Abstract: A stump grinding system that includes a vehicle and a stump grinder adapted to engage with the vehicle. The vehicle has a first end, a second end opposite to the first end, and a longitudinal axis defined therebetween. The stump grinder includes a chassis operably engaged with the vehicle at one of the first end and the second end. The stump grinder also includes a body operably engaged with the chassis and a grinder wheel operably engaged with the body and partially disposed outside of the body from the vehicle. The stump grinder also includes a drive assembly operably engaged with the grinder wheel and the body. The grinder wheel of the stump grinder is configured to rotate in a plane that is orthogonal to the longitudinal axis of the vehicle.

Abstract: A stump grinder for attachment with a vehicle. The stump grinder includes a chassis operably engaged with the vehicle at one of the first end and the second end. The stump grinder also includes a body operably engaged with the chassis. The stump grinder includes a front end positioned proximate to the body, and a rear end positioned proximate to the chassis and opposite to the front end. The stump grinder also includes a grinder wheel operably engaged with the body. The stump grinder also includes a drive assembly operably engaged with the grinder wheel and the body. The stump grinder also includes a push blade assembly operatively engaged with the body, wherein the push blade assembly is independently rotatable on the body between the front end of the body and the rear end of the body.

Abstract: An apparatus, methods, and a system for a photonic biosensor are disclosed. The photonic biosensor includes a substrate having a sample addition zone in fluid communication with a wicking zone and a sample detection zone. The substrate also includes an optical input port configured to optically couple to a light source and an optical output port configured to optically couple to a light detector. The photonic biosensor also includes a photonic integrated circuit (“PIC”) connected to the substrate. The PIC includes a first grating coupler aligned with the optical input port, a second grating coupler aligned with the optical output port, at least one waveguide between the first grating coupler and the second grating coupler, and at least one detection element disposed within the at least one waveguide.

Abstract: New designed ankyrin repeat domains with binding specificity for serum albumin, recombinant binding proteins comprising at least two designed ankyrin repeat domains with binding specificity for serum albumin, as well as recombinant binding proteins comprising at least one designed ankyrin repeat domain with binding specificity for hepatocyte growth factor (HGF), at least one designed ankyrin repeat domain with binding specificity for vascular endothelial growth factor (VEGF-A), and at least two designed ankyrin repeat domain with binding specificity for serum albumin are described, as well as nucleic acids encoding such designed ankyrin repeat domains and recombinant binding proteins, pharmaceutical compositions comprising such designed ankyrin repeat domains, recombinant binding proteins or nucleic acids and the use of such designed ankyrin repeat domains, recombinant binding proteins, nucleic acids or pharmaceutical compositions in the treatment of diseases.

Abstract: A door drive device for adjusting and/or locking a vehicle door relative to a vehicle body including an adjustment member, a drive element operatively coupled to the adjustment member such that the adjustment member is movable with respect to the drive element for moving the vehicle door, a sensor device for measuring a measuring quantity indicative of a movement of the vehicle door to provide a sensor signal, a brake device operatively connected to the drive element for braking a movement of the vehicle door, and a control device for controlling operation of the door drive device. The control device is configured to compute, from the sensor signal obtained from the sensor device, an acceleration value indicative of an acceleration of the vehicle door and evaluate the acceleration value to distinguish movement of the vehicle door caused by a gravity force from movement caused by a user action.

Abstract: The present invention is directed to a biosensor (10) having a photonic sensing device (20), a sheet of a porous material (60), and an optically clear cover layer (70). The optically clear cover layer (70) may be removable and replaceable, whereby the sheet of porous material (60) can be replaced, and the photonic sensing device (20) can be re-used. Detection devices (810, 910) that include the biosensor (10), as well as methods of making and using the biosensor (10) are also disclosed.

Abstract: Device for operating an electric motor, comprising a detection unit for detecting zero-crossings and phase angles of applied phase-shifted sinusoidal voltage phases of a multi-phase power supply network; and a switching unit for connecting half-waves of the applied sinusoidal voltage phases through by means of semiconductor switches in accordance with switching patterns applied to the semiconductor switches, said patterns being synchronised with the detected phase angles and zero-crossings, to generate phase-shifted quasi-sinusoidal voltage phases which are applied directly to the electric motor.

Abstract: New designed ankyrin repeat domains with binding specificity for serum albumin, recombinant binding proteins comprising at least two designed ankyrin repeat domains with binding specificity for serum albumin, as well as recombinant binding proteins comprising at least one designed ankyrin repeat domain with binding specificity for hepatocyte growth factor (HGF), at least one designed ankyrin repeat domain with binding specificity for vascular endothelial growth factor (VEGF-A), and at least two designed ankyrin repeat domain with binding specificity for serum albumin are described, as well as nucleic acids encoding such designed ankyrin repeat domains and recombinant binding proteins, pharmaceutical compositions comprising such designed ankyrin repeat domains, recombinant binding proteins or nucleic acids and the use of such designed ankyrin repeat domains, recombinant binding proteins, nucleic acids or pharmaceutical compositions in the treatment of diseases.

Abstract: Device for operating an electric motor, comprising a detection unit for detecting zero-crossings and phase angles of applied phase-shifted sinusoidal voltage phases of a multi-phase power supply network; and a switching unit for connecting half-waves of the applied sinusoidal voltage phases through by means of semiconductor switches in accordance with switching patterns applied to the semiconductor switches, said patterns being synchronised with the detected phase angles and zero-crossings, to generate phase-shifted quasi-sinusoidal voltage phases which are applied directly to the electric motor.

Abstract: New designed ankyrin repeat domains with binding specificity for serum albumin, recombinant binding proteins comprising at least two designed ankyrin repeat domains with binding specificity for serum albumin, as well as recombinant binding proteins comprising at least one designed ankyrin repeat domain with binding specificity for hepatocyte growth factor (HGF), at least one designed ankyrin repeat domain with binding specificity for vascular endothelial growth factor (VEGF-A), and at least two designed ankyrin repeat domain with binding specificity for serum albumin are described, as well as nucleic acids encoding such designed ankyrin repeat domains and recombinant binding proteins, pharmaceutical compositions comprising such designed ankyrin repeat domains, recombinant binding proteins or nucleic acids and the use of such designed ankyrin repeat domains, recombinant binding proteins, nucleic acids or pharmaceutical compositions in the treatment of diseases.

Abstract: New designed repeat proteins with binding specificity for serum albumin are described, as well as nucleic acids encoding such serum albumin binding proteins, pharmaceutical compositions comprising such proteins, the use of such proteins to modify the pharmacokinetics of therapeutic relevant polypeptides and the use of such proteins in the treatment of diseases. The repeat proteins of the invention have a substantially increased half-life in plasma compared to proteins not binding serum albumin.

Abstract: Fuse load-break switch (1) for low-voltage high-power fuses, a fuse contact pair for receiving a fuse (5A, 5B, 5C) being provided within a housing (2) of the fuse load-break switch (1) for each current phase to be disconnected, characterized in that a thermal power loss brought about by the fuses (5A, 5B, 5C) is dissipated into at least one heat dissipation duct (3) provided laterally on the housing (2) of the fuse load-break switch (1).