Patents by Inventor Daniel Stetson

Daniel Stetson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10501733
    Abstract: The application discloses multimeric assemblies including multiple oligomeric substructures, where each oligomeric substructure includes multiple proteins that self-interact around at least one axis of rotational symmetry, where each protein includes one or more polypeptide-polypeptide interface (“O interface”); and one or more polypeptide domain that is capable of effecting membrane scission and release of an enveloped multimeric assembly from a cell by recruiting the ESCRT machinery to the site of budding by binding to one or more proteins in the eukaryotic ESCRT complex (“L domain”); and where the multimeric assembly includes one or more subunits comprising one or more polypeptide domain that is capable of interacting with a lipid bilayer (“M domain”), as well as membrane-enveloped versions of the multimeric assemblies.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: December 10, 2019
    Assignees: University of Washington, University of Utah Research Foundation
    Inventors: Neil King, Wesley Sundquist, Joerg Votteler, Yang Hsia, David Baker, Jacob Bale, Marc Lajoie, Gabriel Butterfield, Elizabeth Gray, Daniel Stetson
  • Publication number: 20180066312
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Application
    Filed: September 5, 2017
    Publication date: March 8, 2018
    Inventors: Steven Gordon, Daniel Stetson
  • Publication number: 20180030429
    Abstract: The application discloses multimeric assemblies including multiple oligomeric substructures, where each oligomeric substructure includes multiple proteins that self-interact around at least one axis of rotational symmetry, where each protein includes one or more polypeptide-polypeptide interface (“O interface”); and one or more polypeptide domain that is capable of effecting membrane scission and release of an enveloped multimeric assembly from a cell by recruiting the ESCRT machinery to the site of budding by binding to one or more proteins in the eukaryotic ESCRT complex (“L domain”); and where the multimeric assembly includes one or more subunits comprising one or more polypeptide domain that is capable of interacting with a lipid bilayer (“M domain”), as well as membrane-enveloped versions of the multimeric assemblies.
    Type: Application
    Filed: February 29, 2016
    Publication date: February 1, 2018
    Inventors: Neil KING, Wesley SUNDQUIST, Joerg VOTTELER, Yang HSIA, David BAKER, Jacob BALE, Marc LAJOIE, Gabriel BUTTERFIELD, Elizabeth GRAY, Daniel STETSON
  • Patent number: 9790548
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: October 17, 2017
    Assignee: Intelligent Biosystems Inc.
    Inventors: Steven Gordon, Daniel Stetson
  • Publication number: 20140349887
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Application
    Filed: August 11, 2014
    Publication date: November 27, 2014
    Inventors: Steven Gordon, Daniel Stetson
  • Patent number: 8846581
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: September 30, 2014
    Assignee: Intelligent BioSystems, Inc.
    Inventors: Steven Gordon, Daniel Stetson
  • Publication number: 20140235485
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Application
    Filed: February 18, 2014
    Publication date: August 21, 2014
    Applicant: INTELLIGENT BIOSYSTEMS INC.
    Inventors: Steven Gordon, Daniel Stetson
  • Patent number: 8741815
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: June 3, 2014
    Assignee: Intelligent Bio Systems, Inc.
    Inventors: Steven Gordon, Daniel Stetson
  • Patent number: 8455401
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: June 4, 2013
    Assignee: Intelligent Bio-Systems, Inc.
    Inventors: Steve Gordon, Daniel Stetson
  • Publication number: 20130137606
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Application
    Filed: December 6, 2012
    Publication date: May 30, 2013
    Inventors: Steven Gordon, Daniel Stetson
  • Publication number: 20090298131
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Application
    Filed: February 12, 2009
    Publication date: December 3, 2009
    Inventors: Steven Gordon, Daniel Stetson
  • Publication number: 20090227474
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Application
    Filed: February 12, 2009
    Publication date: September 10, 2009
    Inventors: Steven Gordon, Daniel Stetson
  • Publication number: 20090227471
    Abstract: The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
    Type: Application
    Filed: February 12, 2009
    Publication date: September 10, 2009
    Inventors: Steven Gordon, Daniel Stetson
  • Publication number: 20070255295
    Abstract: A device comprises a medical implant and an actively deployable clip attached to the medical implant that operates to restrict movement of the medical implant once the actively deployable clip is deployed within a body of a patient. In some embodiments, the medical implant is an electrical lead for electrical stimulation. The actively deployable clip is operable to fixate the medical implant to a body tissue once deployed, such that the actively deployable clip performs a similar function to a suture. In this manner, embodiments of the invention may provide a medical implant that requires few or even no sutures to properly fixate the implant within the patient.
    Type: Application
    Filed: April 27, 2006
    Publication date: November 1, 2007
    Applicant: Medtronic, Inc.
    Inventors: Warren Starkebaum, Daniel Stetson, Eric Bonde