Patents by Inventor Daniel Steven Johnston

Daniel Steven Johnston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CUT-POINT IN PTEN PROTEIN EXPRESSION THAT ACCURATELY IDENTIFIES TUMORS AND IS PREDICTIVE OF DRUG RESPONSE TO A PAN-ErbB INHIBITOR
    Publication number: 20120010240
    Abstract: A cut-point in the quantitative measurement of PTEN protein expression that accurately identifies tumors with two inactivated alleles of the PTEN gene. Patients with a normalized PTEN score of PTEN null will be treated with a pan-ErbB tyrosine kinase inhibitor. A normalized PTEN protein expression score is obtained by comparing the tumor PTEN OD expression value with the non-malignant PTEN OD expression value.
    Type: Application
    Filed: January 4, 2011
    Publication date: January 12, 2012
    Applicant: Wyeth LLC
    Inventors: Christina Marie Coughlin, Jay Marshall Feingold, Daniel Steven Johnston, Anna Berkenblit, Andrew Louis Strahs, Charles Michael Zacharchuk