Abstract: The present invention provides improved drug-eluting tube devices. In some embodiments, the tube devices deliver analgesics directly at sites of internal discomfort, including, but not limited to, internal membranes and implant entry sites. In some embodiments, the tube devices can be reloaded with drug in situ. In some embodiments, the tube devices comprise lubricating coatings to reduce painful friction with internal membranes. In some embodiments, the tube devices further include flexible and pliable regions that dampen force transmission to implanted sites, such as by inadvertent pulling.

Abstract: A joint prosthesis comprises a first component having a bearing surface and a second component having a bearing surface arranged to articulate with the bearing surface of the first component, said bearing surfaces of the first and the second component thus forming a bearing couple. The bearing surfaces consist of a silicon carbide whisker reinforced alumina. Thus, a bearing couple with low wear, low friction and high hardness is provided.