Abstract: A device for braking and positioning a print sheet in a processing machine, wherein, along a feeding direction for the print sheet, at least one mechanism exerts a braking force onto the print sheet, to position the print sheet in connection with an operation of a downstream-arranged processing station. The device includes at least a first mechanism operative to release pneumatic, braking-force triggering pulses that act upon the print sheet. At least a second mechanism is operative to generate at last one frictional force that acts upon the print sheet, wherein with aid of at least one of the first mechanism and the second mechanism, intermittent, uniform or oscillating braking forces are generated that act upon the print sheet. A control unit controls the braking forces based on at least one of changeable control profiles resulting from queried operating parameters and stored control profiles.

Abstract: A spacer for insulating glazing units is presented. The spacer has a polymeric main body with features that include a first pane contact surface, a second pane contact surface, a first glazing interior surface, a second glazing interior surface, an outer surface, a first hollow chamber, and a second hollow chamber. A groove to accommodate a pane is formed between the first glazing interior surface and the second glazing interior surface, with the first hollow chamber being adjacent the first glazing interior surface and the second hollow chamber being adjacent the second glazing interior surface. Lateral flanks of the groove are formed by walls of the first and second hollow chambers.

Abstract: A device for braking and positioning a print sheet in a processing machine, wherein, along a feeding direction for the print sheet, at least one mechanism exerts a braking force onto the print sheet, to position the print sheet in connection with an operation of a downstream-arranged processing station. The device includes at least a first mechanism operative to release pneumatic, braking-force triggering pulses that act upon the print sheet. At least a second mechanism is operative to generate at last one frictional force that acts upon the print sheet, wherein with aid of at least one of the first mechanism and the second mechanism, intermittent, uniform or oscillating braking forces are generated that act upon the print sheet. A control unit controls the braking forces based on at least one of changeable control profiles resulting from queried operating parameters and stored control profiles.

Abstract: A method for producing a printed product is provided in which a complete content of the printed product is printed sequentially in series on one or both sides along a paper web having a width based on a multiple of a width of a finished printed product. The method comprises cutting the paper web in a longitudinal direction to form at least one partial web having a width based on the width of the finished printed product; cutting the paper web in a direction crosswise to the longitudinal direction of the paper web to form a cut-off section for which a length is based on a multiple of a length of the finished printed product; and folding the partial web at least once in a crosswise direction in a location based on the length of the finished product.

Abstract: A method for producing a printed product in which a complete content of the printed product is printed sequentially in series on one or both sides along a paper web having a width based on a multiple of a width of a finished printed product, including cutting the paper web in a direction crosswise to a longitudinal direction of the paper web to produce a cut-off section having a length based on a multiple of a length of the finished printed product, folding the cut-off section at least once in the crosswise direction in a location based on the length of the finished product, and cutting one of the folded cut-off section subsequent to the folding or the paper web prior to the crosswise cutting, to form a plurality of partial webs each having a width based on the width of the finished printed product.

Abstract: The invention relates to a fireproofing element comprising a fireproof glazed element (1) which forms a window or door leaf (8). A bulkhead frame (3) is arranged around the door leaf (8), inserted in the building (2). A deformable component (28) is built in between the bulkhead frame (3) and the building (2). At least one telescopic element (15) is arranged between a lateral edge (10) of the door leaf (8) and the bulkhead frame (3). Said telescopic element (15) is displaceable relative to the bulkhead frame (3) in the direction of the arrows (20). The telescopic element (15) can compensate for changes in the joint (50) between the door leaf (8) and the bulkhead frame (3) and/or also seal said joint (50). Changes in length as a result of heating of the components during a fire can thus be accommodated and the door leaf (8) and fireproofing glazed element (1) hence not destroyed.

Abstract: A method for producing a printed product in which a complete content of the printed product is printed sequentially in series on one or both sides along a paper web having a width based on a multiple of a width of a finished printed product, including cutting the paper web in a direction crosswise to a longitudinal direction of the paper web to produce a cut-off section having a length based on a multiple of a length of the finished printed product, folding the cut-off section at least once in the crosswise direction in a location based on the length of the finished product, and cutting one of the folded cut-off section subsequent to the folding or the paper web prior to the crosswise cutting, to form a plurality of partial webs each having a width based on the width of the finished printed product.

Abstract: The invention relates to a fireproofing element comprising a fireproof glazed element (1) which forms a window or door leaf (8). A bulkhead frame (3) is arranged around the door leaf (8), inserted in the building (2). A deformable component (28) is built in between the bulkhead frame (3) and the building (2). At least one telescopic element (15) is arranged between a lateral edge (10) of the door leaf (8) and the bulkhead frame (3). Said telescopic element (15) is displaceable relative to the bulkhead frame (3) in the direction of the arrows (20). The telescopic element (15) can compensate for changes in the joint (50) between the door leaf (8) and the bulkhead frame (3) and/or also seal said joint (50). Changes in length as a result of heating of the components during a fire can thus be accommodated and the door leaf (8) and fireproofing glazed element (1) hence not destroyed.

Abstract: The present invention provides a method of upregulating expression of a protein of interest (e.g., a native protein) in a cell, the cell containing a DNA encoding the protein, which DNA contains a mutation that causes downregulation of the protein by aberrant splicing in a pre-mRNA, wherein the DNA encodes the pre-mRNA; wherein the pre-mRNA contains a native intron having a first set of splice elements, which native intron is removed by splicing when the mutation is absent to produce a first mRNA encoding the protein; and wherein the pre-mRNA further contains an aberrant intron different from the native intron having a second set of splice elements, which aberrant intron is removed by splicing when the mutation is present to produce an aberrant second mRNA different from the first mRNA.

Abstract: The present invention provides a method of upregulating expression of a protein of interest (e.g., a native protein) in a cell, the cell containing a DNA encoding the protein, which DNA contains a mutation that causes downregulation of the protein by aberrant splicing in a pre-mRNA, wherein the DNA encodes the pre-mRNA; wherein the pre-mRNA contains a native intron having a first set of splice elements, which native intron is removed by splicing when the mutation is absent to produce a first mRNA encoding the protein; and wherein the pre-mRNA further contains an aberrant intron different from the native intron having a second set of splice elements, which aberrant intron is removed by splicing when the mutation is present to produce an aberrant second mRNA different from the first mRNA.

Abstract: A method is taught for preparing a coating hopper prior to initiation of coating a liquid coating composition at a predetermined coating flow rate onto a moving substrate wherein the coating hopper includes at least one internal flow path therethrough. The internal flow path(s) of the coating hopper are drained. The liquid coating composition is introduced into internal flow path(s) at a purge flow rate which may be determined empirically. The internal flow path(s) are filled with the liquid coating composition and with the liquid coating composition then discharging from the internal flow path(s) onto a slide surface of the coating hopper, the liquid coating composition flowing down the slide surface and over a lip of the coating hopper at the purge rate to a drain. The flow of the liquid coating composition through the internal flow path(s) is maintained at the purge rate until air within the internal flow path(s) has been displaced from the coating hopper.