Patents by Inventor Daniel T. Chu

Daniel T. Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of racemate and optically active ofloxacin and related derivatives
    Patent number: 4777253
    Abstract: A process for producing racemic or optically active compounds of the formula: ##STR1## wherein R.sub.1 is hydrogen, C.sub.1 to C.sub.6 alkyl or benzyl; and Z is amino or substituted amino.Also disclosed are intermediates useful in the process and methods for producing the intermediates.
    Type: Grant
    Filed: April 25, 1986
    Date of Patent: October 11, 1988
    Assignee: Abbott Laboratories
    Inventors: Lester A. Mitscher, Daniel T. Chu
  • Quinoline antibacterial compounds
    Patent number: 4774246
    Abstract: Quinoline compounds having the formula: ##STR1## wherein R is a phenyl or substituted phenyl group or an aromatic heterocyclic group, R.sub.1 is a hydrogen or a carboxy-protecting group and Z is an amine group or an aliphatic heterocyclic group. The compounds have antibacterial activity.
    Type: Grant
    Filed: September 12, 1986
    Date of Patent: September 27, 1988
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Tricyclic quinoline and naphthyride antibacterials
    Patent number: 4767762
    Abstract: This invention relates to novel isoxazolo-naphthyridine, isoxazolo-quinoline, isothiazolo-naphthyridine, and isothiazolo-quinoline, derivatives having antibacterial properties.
    Type: Grant
    Filed: December 11, 1986
    Date of Patent: August 30, 1988
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • 7-(3-Substituted imino-1-pyrrolidinyl)-quinolone-3-carboxylic acids
    Patent number: 4762845
    Abstract: New 7-substituted 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acids or esters having a substituted or unsubstituted phenyl radical, an aromatic heterocyclic radical, an alkyl or cycloalkyl radical in the 1-position are antibacterial agents.
    Type: Grant
    Filed: May 21, 1986
    Date of Patent: August 9, 1988
    Assignee: Abbott Laboratories
    Inventors: Daniel T. Chu, Andre G. Pernet, Curt S. Cooper
  • Quinoline antibacterial compounds
    Patent number: 4730000
    Abstract: Quinoline compounds having the formula: ##STR1## wherein R is a phenyl group or an aromatic heterocyclic group, Z is an aliphatic heterocyclic group or an amine, and R.sub.1 is hydrogen or a carboxy-protecting group. The compounds here disclosed have antibacterial properties.
    Type: Grant
    Filed: October 7, 1985
    Date of Patent: March 8, 1988
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives
    Patent number: 4689325
    Abstract: This invention relates to novel isoxazolo-pyrido-phenoxazine and isothiazolo-pyridophenoxazine derivatives having antibacterial properties and compositions containing methods of treating mammalian patients with these new derivatives.
    Type: Grant
    Filed: October 15, 1986
    Date of Patent: August 25, 1987
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives
    Patent number: 4687770
    Abstract: This invention relates to novel isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives having antibacterial properties.
    Type: Grant
    Filed: October 15, 1986
    Date of Patent: August 18, 1987
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Naphthyridine antibacterial compounds
    Patent number: 4616019
    Abstract: Naphthyridine compounds having the formula: ##STR1## wherein Z is an amine or an aliphatic heterocyclic group, R is a phenyl group or an aromatic heterocyclic group and R.sub.1 is hydrogen or a carboxy protecting group. The compounds of the invention have antibacterial activity.
    Type: Grant
    Filed: October 4, 1985
    Date of Patent: October 7, 1986
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Quino-benoxazine antibacterial compounds
    Patent number: 4607032
    Abstract: Quino-benoxazine compounds having the formula: ##STR1## wherein R.sub.2 is one or more substituents, R.sub.1 is a hydrogen or a carboxy-protecting group and Z is an amine group or an aliphatic heterocyclic group. The compounds have antibacterial activity.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: August 19, 1986
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Methylenedioxy quino-benoxazine derivatives and antibacterial use
    Patent number: 4542133
    Abstract: 1,2-methylenedioxy quino-benoxazine derivatives having the formula: ##STR1## wherein R.sub.2 is a substituent and R.sub.1 is hydrogen or a carboxy protecting group. The compounds of the invention have antibacterial activity.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: September 17, 1985
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • 1-Pyridine substituted quino-benoxazines and antibacterial use
    Patent number: 4540694
    Abstract: 1-pyridine substituted quino-benoxazines having the formula: ##STR1## wherein X is halogen or hydrogen; R.sub.2 is a substituent; and R.sub.1 is hydrogen or a carboxy protecting group.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: September 10, 1985
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Quino-benzothiazine antibacterial compounds
    Patent number: 4533663
    Abstract: Quino-benzothiazine compounds having the formula ##STR1## wherein R.sub.2 is one or more constituents; R.sub.1 is a hydrogen or a carboxy-protecting group; and Z is an amine group or an aliphatic heterocyclic group. The compounds have antibacterial activity.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: August 6, 1985
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • 1-pyridine substituted quino-benzothiazine
    Patent number: 4529725
    Abstract: 1-pyridine substituted quino-benzothiazine having the formula: ##STR1## wherein X is halogen or hydrogen; R.sub.2 is a substituent; and R.sub.1 is hydrogen or a carboxy protecting group.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: July 16, 1985
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Methylenedioxy quino-benzothiazine derivatives
    Patent number: 4528285
    Abstract: 1,2-methylenedioxy quino-benzothiazine derivatives having the formula ##STR1## wherein R.sub.2 is a substituent and R.sub.1 is hydrogen or a carboxy protecting group. The compounds of the invention have antibacterial activity.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: July 9, 1985
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Inhibitors of transpeptidase
    Patent number: 4397784
    Abstract: New .beta.-lactams of the general structure: ##STR1## wherein X=O or S; R represents H, loweralkyl, acyl, aryl, or arylloweralkyl; R' is hydrogen, loweralkoxy, loweralkoxyalkyl, loweralkyl, phenylthio or loweralkylmercapto; R" is hydrogen or loweralkyl; and the broken line represents an optional double bond, and certain esters thereof. All compounds are effective antibacterials.
    Type: Grant
    Filed: January 4, 1982
    Date of Patent: August 9, 1983
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Inhibitors of transpeptidase
    Patent number: 4347355
    Abstract: New .beta.-lactams of the general structure: ##STR1## wherein R represents H or an acyl moiety known from the penicillin or cephalosporin art, R' is hydrogen, loweralkoxy, loweralkoxyalkyl, loweralkyl, phenylthio or loweralkylmercapto R" is loweralkyl, the broken line represents an optional double bond, and acyloxymethyl esters thereof. All compounds are effective antibacterials.
    Type: Grant
    Filed: December 1, 1980
    Date of Patent: August 31, 1982
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Antibacterial peptides
    Patent number: 4309342
    Abstract: It has been found that dipeptides containing a 3-fluoro-D-alanine N-terminus are powerful antibacterials and produce a highly useful synergistic effect with antibiotics.
    Type: Grant
    Filed: July 3, 1980
    Date of Patent: January 5, 1982
    Assignee: Abbott Laboratories
    Inventors: Daniel T. Chu, Jerry R. Martin, Alford M. Thomas