Abstract: High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Biologically active agents may be entrapped in pores of materials to provide a controlled release of the biologically active agent.

Abstract: Articles, such as catheters, comprising markings and associated methods are generally provided. The articles described herein may be configured to be exhibit one or more desirable properties. For instance, in some embodiments, an article comprises markings that are spaced from each other at known distances. Such markings may be employed to aid users of the article in measuring distances. As another example, an article may be configured to swell upon exposure to the fluid such that markings positioned thereon do not crack or delaminate. It is also possible for the article to be configured to swell upon exposure to the fluid in a known, predictable, and/or uniform manner. This swelling may cause the spacings between the markings to increase, and such increase may also be in a known, predictable, and/or uniform manner.

Abstract: Articles and/or integrated articles comprising a body portion (e.g., a catheter) and a component (e.g., a cuff) physically integrated with the body portion are generally provided. For example, materials, methods, and uses are set forth herein for forming a body portion comprising a first material physically integrated with a component comprising a second material, same or different, than the first material. The disclosed compositions and devices may be useful for administration to a subject (e.g., a patient). Advantageously, the compositions and/or devices described herein may be substantially non-thrombogenic, lubricious, and/or biocompatible. In some embodiments, the devices described herein may be useful for the delivery of a biologically active agent (e.g., a therapeutic agent such as a drug) to a subject. Methods for forming such compositions and/or devices are also provided.

Abstract: Articles and/or integrated articles comprising a body portion (e.g., a catheter) and a component (e.g., a cuff) physically integrated with the body portion are generally provided. For example, materials, methods, and uses are set forth herein for forming a body portion comprising a first material physically integrated with a component comprising a second material, same or different, than the first material. The disclosed compositions and devices may be useful for administration to a subject (e.g., a patient). Advantageously, the compositions and/or devices described herein may be substantially non-thrombogenic, lubricious, and/or biocompatible. In some embodiments, the devices described herein may be useful for the delivery of a biologically active agent (e.g., a therapeutic agent such as a drug) to a subject. Methods for forming such compositions and/or devices are also provided.

Abstract: Articles and/or integrated articles comprising a body portion (e.g., a catheter) and a component (e.g., a cuff) physically integrated with the body portion are generally provided. For example, materials, methods, and uses are set forth herein for forming a body portion comprising a first material physically integrated with a component comprising a second material, same or different, than the first material. The disclosed compositions and devices may be useful for administration to a subject (e.g., a patient). Advantageously, the compositions and/or devices described herein may be substantially non-thrombogenic, lubricious, and/or biocompatible. In some embodiments, the devices described herein may be useful for the delivery of a biologically active agent (e.g., a therapeutic agent such as a drug) to a subject. Methods for forming such compositions and/or devices are also provided.

Abstract: Articles, such as catheters, comprising markings and associated methods are generally provided. The articles described herein may be configured to be exhibit one or more desirable properties. For instance, in some embodiments, an article comprises markings that are spaced from each other at known distances. Such markings may be employed to aid users of the article in measuring distances. As another example, an article may be configured to swell upon exposure to the fluid such that markings positioned thereon do not crack or delaminate. It is also possible for the article to be configured to swell upon exposure to the fluid in a known, predictable, and/or uniform manner. This swelling may cause the spacings between the markings to increase, and such increase may also be in a known, predictable, and/or uniform manner.

Abstract: High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Polymers may be entrapped in pores of materials to provide a durable modification of the materials.

Abstract: High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces.

Abstract: Articles, such as catheters, comprising markings and associated methods are generally provided. The articles described herein may be configured to be exhibit one or more desirable properties. For instance, in some embodiments, an article comprises markings that are spaced from each other at known distances. Such markings may be employed to aid users of the article in measuring distances. As another example, an article may be configured to swell upon exposure to the fluid such that markings positioned thereon do not crack or delaminate. It is also possible for the article to be configured to swell upon exposure to the fluid in a known, predictable, and/or uniform manner. This swelling may cause the spacings between the markings to increase, and such increase may also be in a known, predictable, and/or uniform manner.

Abstract: Packaging for hydrated articles are generally provided. In some embodiments, packaged articles are provided. For example, in some embodiments, a container contains an article such as a catheter and/or polymeric material. The disclosed packaged articles may be useful for, for example, providing controlled humidity conditions for contained components, maintaining consistent hydration levels of the packaged articles, and/or improved sterilization conditions. Advantageously, the packaged articles described herein may, in some embodiments, create an environment with minimum relative humidity for long-term storage of a catheter or polymeric material, increase shelf life of the catheter or polymeric material, and/or facilitate hydration of a catheter such that e.g., the catheter hydrates to intended dimensions within a specified amount of time. Methods for preparing such packaged article are also provided.

Abstract: High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Biologically active agents may be entrapped in pores of materials to provide a controlled release of the biologically active agent.