Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.

Abstract: The invention relates to a container (1), preferably a bottle, which extends along a main axis (A) and comprising a wall forming a neck portion (2), a shoulder portion (3) connected to the neck portion (2), a body portion (4) connected to the shoulder portion (3), the body portion (4) comprising a grip portion (7), and a base portion (5) forming the bottom of the container (1) and connected to the body portion (4). The grip portion (7) comprises, over at least the majority of its dimension along the main axis (A), a plurality of spiral ribs (13) formed by the wall of the container (1) and spiralling in parallel around the main axis (A). The spiral ribs drastically increase side stability, compression and twisting deformation resistance of the container, while they have a non-technical and appealing appearance.

Abstract: A packaging assembly includes a top section, a bottom section releasably connected by at least one fastener. The top section includes a top body defining a label opening and a transparent label cover closing the label opening. The top section is configured to removably retain a shipping label under the transparent label cover. The bottom section includes a bottom body, at least a first package recess being defined in the bottom section that removably accommodates at least a first internal package therein. The first package recess has a first recess width approximately equal to a first package width. A user releases the fastener to open the top and bottom sections and remove the internal package. The shipping label is removed, manipulated to display a return address and reinserted under the label cover so the packaging assembly can be returned.

Abstract: A food assembly line is provided for assembling a food item according to an order. The food assembly line includes multiple work stations at which the food item may be positioned, and a display system including a display device at each of the multiple work stations. The display system is configured to display information associated with the order at the display devices. The display system is further configured to update the display devices during assembly of the food item so that each display device displays at least a portion of the information when the food item is positioned proximate the display device.