Abstract: A replacement heart valve comprises a unibody, folded, double-wall stent, with a stent cover and a leaflet valve attached to the inner lumen of the stent. The heart valve is delivered using a multi-pulley, suture-based stent restraint assembly provided by fixed guide openings or structures along the distal end of the delivery system that independently permits expansion of the distal and proximal ends of the outer wall of the stent, and control of the inner wall expansion simultaneously with or separately from the expansion of the outer wall.

Abstract: Delivery systems for expandable and stented implants include tensioning members that are attached to rotors with hook-like attachment projections are wound onto the shaft of the delivery system, which is then rotated to unwind the tensioning members and incrementally expand the implant.

Abstract: A valve repair device, e.g., for treating mitral valve regurgitation, includes a tubular body defining a longitudinal axis, paddles supported by the tubular body and movable to change abduction of the paddles relative to the longitudinal axis, and retention members supported by the tubular body proximal the paddles and similarly movable to change abduction of the retention members relative to the longitudinal axis to facilitate capture of native valve leaflets between pairs of paddles and retention members. Movement of the paddles and/or retention members is provided by one or more control mechanisms including a collar a shaft extending within the tubular body. Each shaft is threadedly engaged to a respective collar and coupled to one or more of the movable elements such that, when the collar is rotated, the shaft translates to change abduction of the movable element relative to the longitudinal axis.

Abstract: Certain aspects relate to systems and techniques for articulating medical instruments. In one aspect, the instrument includes a wrist having at least two degrees of freedom of movement, and an end effector coupled to the wrist. The end effector can include an upper jaw, a lower jaw, and a firing mechanism configured to form staples in tissue. Actuation of the firing mechanism can be decoupled from the movement of the wrist in the at least two degrees of freedom.

Abstract: A delivery device for cardiac valve repair implants includes a delivery catheter, a sheath extending around the delivery catheter and including a distal opening, and a control arm assembly releasably coupleable to a cardiac valve repair implant and configured to selectively expand the frame of the cardiac valve repair implant. The sheath is translatable relative to the delivery catheter and control arm assembly from a distal position to a proximal position and the control arm assembly is configured to be coupled to the cardiac valve repair implant such that, with the sheath in the distal position, a central occluder of the cardiac valve repair implant protrudes from the distal opening and a frame of the cardiac valve repair implant is retained within the sheath. In the former configuration, the occluder may provide a temporary nosecone for the delivery device.

Abstract: Delivery systems for expandable and stented implants include adjustable tensioning members that control the expansion of the implant along the length of the implant. The tensioning members are wound onto one or more rotors located on the distal segment of the delivery system, which are rotated to unwind the tensioning members and incrementally expand the implant. Positioning mechanisms are also provided to adjust the position and orientation of the implant during delivery.

Abstract: A valve repair device, e.g., for treating mitral valve regurgitation, includes a tubular body defining a longitudinal axis, paddles supported by the tubular body and movable to change abduction of the paddles relative to the longitudinal axis, and retention members supported by the tubular body proximal the paddles and similarly movable to change abduction of the retention members relative to the longitudinal axis to facilitate capture of native valve leaflets between pairs of paddles and retention members. Movement of the paddles and/or retention members is provided by one or more control mechanisms including a collar a shaft extending within the tubular body. Each shaft is threadedly engaged to a respective collar and coupled to one or more of the movable elements such that, when the collar is rotated, the shaft translates to change abduction of the movable element relative to the longitudinal axis.

Abstract: A replacement heart valve comprises a unibody, folded, double-wall stent, with a stent cover and a leaflet valve attached to the inner lumen of the stent. The heart valve is delivered using a multi-pulley, suture-based stent restraint assembly provided by fixed guide openings or structures along the distal end of the delivery system that independently permits expansion of the distal and proximal ends of the outer wall of the stent, and control of the inner wall expansion simultaneously with or separately from the expansion of the outer wall.

Abstract: Delivery systems for expandable and stented implants include tensioning members that are attached to rotors with hook-like attachment projections are wound onto the shaft of the delivery system, which is then rotated to unwind the tensioning members and incrementally expand the implant.

Abstract: The embodiments herein are directed to replacement valve comprising a double-wall, folded stent structure with an inner wall providing an inner lumen and a valve structure that is attached to a stent structure. The inner wall is spaced apart from an outer wall that is configured to seal and/or anchor to the surround native valve anatomy, but is contiguous with the inner wall via a transition wall. The transition wall may result from the folding, inversion or eversion of a single tubular structure into a double-wall unibody tubular stent structure. The stent structure is configured to reversibly collapse into a collapsed configuration exhibiting reduced diameter or reduced cross-sectional shape for loading into a catheter and for delivery to a target anatomical site and an expanded configuration.

Abstract: A delivery device for cardiac valve repair implants includes a delivery catheter, a sheath extending around the delivery catheter and including a distal opening, and a control arm assembly releasably coupleable to a cardiac valve repair implant and configured to selectively expand the frame of the cardiac valve repair implant. The sheath is translatable relative to the delivery catheter and control arm assembly from a distal position to a proximal position and the control arm assembly is configured to be coupled to the cardiac valve repair implant such that, with the sheath in the distal position, a central occluder of the cardiac valve repair implant protrudes from the distal opening and a frame of the cardiac valve repair implant is retained within the sheath. In the former configuration, the occluder may provide a temporary nosecone for the delivery device.

Abstract: Provided are systems and techniques for a medical procedure. For example, the system may include one or more robotic arms, an imaging device, a master controller, a viewer configured to render one or more digital images based on image data from the imaging device, at least one computer-readable memory having stored thereon executable instructions, and one or more processors. The one or more processors may be configured to execute the instructions to cause the system to: in a first mode of operation, cause movement of at least one of the robotic arms; and in a second mode of operation, cause the viewer to display an interactive menu and a graphical overlay on the one or more digital images.

Abstract: A system for delivery of cardiac implants includes a catheter having a handle assembly including a cable control assembly. The handle assembly further includes a tubular body assembly extending distally from the handle assembly and deflectable by operation of the cable control assembly. The system also includes a robot having a linear displacement platform and a carriage coupled to the linear displacement platform. The carriage includes a drive motor assembly and is at least one of linearly displaceable along the linear displacement platform and rotatable relative to the linear displacement platform. The handle assembly is coupled to the carriage such that the cable control assembly interfaces with the drive motor assembly of the carriage to facilitate operation of the cable control assembly by the robot.

Abstract: A delivery device for cardiac valve repair implants includes a delivery catheter, a sheath extending around the delivery catheter and including a distal opening, and a control arm assembly releasably coupleable to a cardiac valve repair implant and configured to selectively expand the frame of the cardiac valve repair implant. The sheath is translatable relative to the delivery catheter and control arm assembly from a distal position to a proximal position and the control arm assembly is configured to be coupled to the cardiac valve repair implant such that, with the sheath in the distal position, a central occluder of the cardiac valve repair implant protrudes from the distal opening and a frame of the cardiac valve repair implant is retained within the sheath. In the former configuration, the occluder may provide a temporary nosecone for the delivery device.

Abstract: A replacement heart valve comprises a unibody, folded, double-wall stent, with a stent cover and a leaflet valve attached to the inner lumen of the stent. The heart valve is delivered using a multi-pulley, suture-based stent restraint assembly provided by fixed guide openings or structures along the distal end of the delivery system that independently permits expansion of the distal and proximal ends of the outer wall of the stent, and control of the inner wall expansion simultaneously with or separately from the expansion of the outer wall.

Abstract: A robotic system can include a surgical instrument with a wrist including an elongate shaft extending between a proximal end and a distal end, a wrist extending from the distal end of the elongate shaft, and an end effector extending from the wrist. The end effector may include a first jaw and a second jaw, the first and second jaw being moveable between an open position in which ends of the jaws are separated from each other, and a closed position in which the ends of the jaws are closer to each other as compared to the open position. The surgical instrument may also include at least one rotary cutter extending from the wrist and positioned at least partially within a recess formed in a face of the first jaw.

Abstract: A valve implant includes an occlusive assembly and a frame coupled to the occlusive assembly. The frame transitions from a collapsed state to an expanded state about a central longitudinal axis and transitioning from the collapsed state to the expanded state causes a proximal end of the frame to expand radially outward from the central longitudinal axis. The valve implant further includes an outer sheet supported on a proximal portion of the frame. The occlusive assembly is supported on a distal portion of the frame such that the inner sheet extends about the central longitudinal axis and an annular opening is defined between the outer sheet and the inner sheet when the frame is in the expanded state.

Abstract: Provided are systems and techniques for a medical procedure. For example, the system may include one or more robotic arms, an imaging device, a master controller, a viewer configured to render one or more digital images based on image data from the imaging device, at least one computer-readable memory having stored thereon executable instructions, and one or more processors. The one or more processors may be configured to execute the instructions to cause the system to: in a first mode of operation, cause movement of at least one of the robotic arms; and in a second mode of operation, cause the viewer to display an interactive menu and a graphical overlay on the one or more digital images.

Abstract: Delivery systems for expandable and stented implants include tensioning members that are attached to rotors with hook-like attachment projections are wound onto the shaft of the delivery system, which is then rotated to unwind the tensioning members and incrementally expand the implant.

Abstract: A system for delivery of cardiac implants includes a catheter having a handle assembly including a cable control assembly. The handle assembly further includes a tubular body assembly extending distally from the handle assembly and deflectable by operation of the cable control assembly. The system also includes a robot having a linear displacement platform and a carriage coupled to the linear displacement platform. The carriage includes a drive motor assembly and is at least one of linearly displaceable along the linear displacement platform and rotatable relative to the linear displacement platform. The handle assembly is coupled to the carriage such that the cable control assembly interfaces with the drive motor assembly of the carriage to facilitate operation of the cable control assembly by the robot.