Patents by Inventor Daniel Tamae

Daniel Tamae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG
    Publication number: 20220331273
    Abstract: Methods of quantifying a N2-(1-carboxyethyl)-2?-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of metabolic disorders or complications associated therewith, including diabetes, its associated complications, and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels is achieved by using liquid chromatography electrospray ionization tandem mass spectrometry.
    Type: Application
    Filed: November 22, 2021
    Publication date: October 20, 2022
    Applicant: CITY OF HOPE
    Inventors: Samuel RAHBAR, Timothy W. SYNOLD, John TERMINI, Gerald WUENSCHELL, Daniel TAMAE, Sarah SHUCK
  • Methods of quantifying N-(1-carboxyethyl)-2?-deoxy-guanosine (CEdG) and synthesis of oligonucleotides containing CEdG
    Patent number: 11266618
    Abstract: Methods of quantifying N2-carboxyethyl-2?-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of disorders, including diabetes and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels occurs using liquid chromatography electrospray ionization tandem mass spectrometry.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: March 8, 2022
    Assignee: CITY OF HOPE
    Inventors: Samuel Rahbar, Timothy W. Synold, John Termini, Daniel Tamae, Gerald Wuenschell
  • Methods of quantifying N-(1-carboxyethyl)-2?-deoxy-guanosine (CEdG) and synthesis of oligonucleotides containing CEdG
    Patent number: 11179361
    Abstract: Methods of quantifying a N2-(1-carboxyethyl)-2?-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of metabolic disorders or complications associated therewith, including diabetes, its associated complications, and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels is achieved by using liquid chromatography electrospray ionization tandem mass spectrometry.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: November 23, 2021
    Assignee: CITY OF HOPE
    Inventors: Samuel Rahbar, Timothy W. Synold, John Termini, Gerald Wuenschell, Daniel Tamae