Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.

Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.

Abstract: An implantable cuff includes an elastic collar, at least one conductive segment disposed on or within the elastic collar, and at least one conductor in electrical communication with the at least one conductive segment. The elastic collar defines an internal opening configured to receive an internal body tissue. At least a portion of the elastic collar includes a stiffening region having a stiffness greater than a second region of the elastic collar. The at least one conductor is configured to operably mate with an apparatus capable of delivering electrical stimulation to, and/or recording an electrical activity of, the internal body tissue.

Abstract: Defining proximal as toward the heart and distal as away from the heart, a sheath includes a proximal opening and multiple fenestrations maintainable in position slightly beyond a site or point of sheath entry into a vessel by way of an anchoring assembly having a set of radially displaceable anchoring elements configured for abutting a superficial vessel wall. The fenestrations and/or anchoring element(s) are arranged obliquely or non-obliquely around peripheral portions of the sheath. The sheath can receive blood from a pumping source at a proximal opening, and channel the blood toward, to, and through the fenestrations. The fenestrations, in combination with the proximal opening, enable the perfusion of blood into the cannulated vessel in a set of distal directions for perfusing a distal tissue or organ. Flow of blood out of fenestrations directs blood distally towards the limb, head, or other distal region, mitigating the risk of or preventing ischemia.

Abstract: A cannula includes a first segment configured to reside entirely within a vessel. The first segment includes a proximal exit opening disposed nearer to the heart, and multiple fenestrations disposed distally away from the proximal exit opening near a cannulation site. The fenestrations in combination with the proximal exit opening enable simultaneous perfusion of blood into the cannulated vessel along proximal and distal directions. During a medical procedure, blood introduced into a vessel (e.g., the femoral artery) by way of the cannula can exit the cannula in a manner that provides concurrent blood flow in a first set of directions proximally towards the heart and a second set of directions distally away from the heart. Radially displaceable anchoring elements positionable adjacent to the vessel's superficial wall aid retention of the first segment in the vessel. The fenestrations and/or anchoring elements can be arranged obliquely around portions of the cannula's circumference.

Abstract: The present invention generally relates to patterned intensity modulation of neural tissue. Certain embodiments provide a method of treating medical conditions by providing an electrode and modulating stimulation parameters delivered by the electrode. The stimulation parameters that are modulated relate to stimulation intensity and are varied according to a stimulation input parameter or time. The stimulation input parameter can be a choice of an individual waveform (i.e. ? or psi), which may be varied for each pulse.

Abstract: The present invention generally relates to patterned intensity modulation of neural tissue. Certain embodiments provide a method of treating medical conditions by providing an electrode and modulating stimulation parameters delivered by the electrode. The stimulation parameters that are modulated relate to stimulation intensity and are varied according to a stimulation input parameter or time. The stimulation input parameter can be a choice of an individual waveform (i.e. ? or psi), which may be varied for each pulse.

Abstract: A multi-web application management framework system and method is disclosed. A method for managing multiple web applications using a client-side application management framework system can comprise the steps wrapping an application in an isolation container using an isolation service stored in a memory, and storing the application in the isolation container in the memory. A client computer within a system for managing multiple web application can comprise a processor and a memory. The processor can, at the direction of an isolation service, wrap an application in an isolation container. The memory can store a client-side application management framework. The client-side application management framework can comprise the isolation container, and the isolation container can comprise the application. The memory can also comprise a client-side application service. The client-side application service can be an isolation service.

Abstract: An implantable cuff includes an elastic collar, at least one conductive segment disposed on or within the elastic collar, and at least one conductor in electrical communication with the at least one conductive segment. The elastic collar defines an internal opening configured to receive an internal body tissue. At least a portion of the elastic collar includes a stiffening region having a stiffness greater than a second region of the elastic collar. The at least one conductor is configured to operably mate with an apparatus capable of delivering electrical stimulation to, and/or recording an electrical activity of, the internal body tissue.

Abstract: A computer system may manage orders for goods from a plurality of purchasers. The computer system may receive the orders, calculate an approximate volume that the goods which are the subject of each order would collectively occupy during shipment, and compare each calculated approximate volume to a pre-determine maximum allowed volume that the purchaser of the order is permitted. The computer system may accept each order whose approximate volume does not exceed the maximum allowed volume for the purchaser of the order, or reject each order whose approximate volume exceeds this maximum allowed volume.

Abstract: An apparatus (1) for removing a needle from a syringe comprising a housing (20, 30); a sliding member (10) slidingly engaged within said housing (20,30), said sliding member (10) having a recess (5) for receiving the needle mounted to the syringe; at least two gripping members (40) in communication with the sliding member (10) such that on sliding the sliding member (10) within the housing (20,30), the gripping members (40) progressively converge, wherein the gripping members (40) are positioned such that a point of convergence of the gripping members (40) coincides with a portion on the needle to grip said needle.

Abstract: A computer system may manage orders for goods from a plurality of purchasers. The computer system may receive the orders, calculate an approximate volume that the goods which are the subject of each order would collectively occupy during shipment, and compare each calculated approximate volume to a pre-determine maximum allowed volume that the purchaser of the order is permitted. The computer system may accept each order whose approximate volume does not exceed the maximum allowed volume for the purchaser of the order, or reject each order whose approximate volume exceeds this maximum allowed volume.

Abstract: A method of forming multiple bonds on an electronic device includes heating first bonding metals at a predetermined temperature to form a first bond comprising a first melting temperature above the predetermined temperature. The first bond and second bonding metals are then heated at the predetermined temperature to form a second bond comprising a second melting temperature above the predetermined temperature.

Abstract: A voltage excursion control system for limiting transient voltage peaks in electrical circuits otherwise occurring across selected components therein in response to changing conditions in such circuits has a plurality of silicon carbide diode dice series-interconnected in a succession such that each cathode region of each die face toward a common end of the succession. First and second electrically conductive electrodes are each electrically interconnected with a corresponding one of the dice at opposite ends of the succession.

Abstract: The present invention provides a bag comprising front and rear walls, each wall having left and right side edges, an upper edge, and a bottom edge, wherein the front and rear walls are integrally joined at their left and right side edges and are secured together at their bottom edges. The front and rear walls further define an upper edge that defines a bag opening for use in inserting items into the bag, a pair of spaced apart handles, and one or more tie tabs disposed along an upper edge of the bag.

Abstract: A plurality of stacked polyethylene film bags comprising about 40-48 wt. % high density, high molecular weight polyethylene, 12-20 wt. % high density, medium molecular weight polyethylene, 20-30 wt. % linear low density polyethylene, 0-8 wt. % color concentrate, are releasably adhered together in substantial registration. Each of the bags includes front and rear polyethylene film walls and each of the front and rear walls have first and second side edges, a top edge and a bottom edge. The front and rear walls are integrally joined at their first and second side edges and secured together at their bottom edges. An open mouth portion is defined adjacent the top edges of the bag. At least an upper portion of the outer surface of the front and rear walls of each of the bags has been corona treated. T-shirt style bags using the above formulation are also described.

Abstract: The present invention relates generally to impairment detection and compensation in a communications network. One embodiment includes a method for generating an adaptive Digital Impairment Learning (DIL) sequence for use in a training mode which assists in resolving digital loss ambiguities affecting the mapping of analog levels to digital levels in a communications network. The method includes identifying a feature octet for a pair of the digital loss ambiguities, determining a number of transmit copies of the feature octet based at least in part upon a noise variance, and modifying a standard DIL sequence with the number of transmit copies of the feature octet to produce the adaptive DIL sequence for use in the training mode. Alternate embodiments relate to an apparatus for generating an adaptive DIL sequence for use in a training mode and an apparatus and method for compensating for digital losses in a communications network.