Abstract: The present disclosure provides DNA-guided CRISPR systems; polynucleotides comprising DNA, RNA and mixtures thereof for use with CRISPR systems; and methods of use involving such polynucleotides and DNA-guided CRISPR systems.

Abstract: The present disclosure provides shuttle vectors for editing exogenous polynucleotides in heterologous live cells, as well as automated methods, modules, and multi-module cell editing instruments and systems for performing the editing methods.

Abstract: A services platform acts as an intermediary between an existing enterprise analytic environment, and one or more underlying cloud service providers. The platform provides enterprise “big data-as-a-service,” by which an enterprise can seamlessly and easily provision new capacity for processing its analytic workload, and migrate data sources (e.g., data warehouse marts, enterprise data warehouses, analytic sandboxes, and the like) to the cloud for processing. The platform provides end-to-end enterprise class manageability of enterprise data assets, from data collection, aggregation, movement, staging and processing, all while providing service levels, security, access and governance. The platform integrates directly but seamlessly into the enterprise analytic stack, and existing analytics applications work as normal. The platform provides a way for the enterprise to translate its workloads into clusters of compute resources that meet its service level requirements.

Abstract: A conventional gasoline engine is retrofitted and calibrated to operate as a bi-fuel engine using Hydrogen as the second fuel. When operated with Hydrogen, which typically leads to a reduction of engine output power, the engine is preferably operated in a charged mode and in a lean mode with the engine throttle kept in a wide open position during charged and lean mode operation resulting in a more efficient engine with a reduction of engine output power loss.

Abstract: The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.

Abstract: According to various aspects, a collision avoidance method may include: receiving depth information of one or more depth imaging sensors of an unmanned aerial vehicle; determining from the depth information a first obstacle located within a first distance range and movement information associated with the first obstacle; determining from the depth information a second obstacle located within a second distance range and movement information associated with the second obstacle, the second distance range is distinct from the first distance range, determining a virtual force vector based on the determined movement information, and controlling flight of the unmanned aerial vehicle based on the virtual force vector to avoid a collision of the unmanned aerial vehicle with the first obstacle and the second obstacle.

Abstract: A computing system includes persistent storage and a discovery application configured to perform operations including obtaining, from a remote computing system, first attributes of a first computing resource, which indicate a first unique resource identifier associated with an authentication system provided by the remote computing system and utilized by the first computing resource. The operations also include obtaining, from the remote computing system, second attributes of the authentication system, which indicate a second unique resource identifier used by the authentication system. The operations additionally include determining that the first unique resource identifier matches the second unique resource identifier and, based on this determination, generating a mapping between the first computing resource and the authentication system to indicate that access to the first computing resource is controlled by the authentication system.

Abstract: Methods, systems, and apparatuses are disclosed for the selective and controlled removal of debris from specific areas of a substrate outer surface without adversely impacting the substrate outer surface, including substrate outer surface coatings, and returning an actual substrate outer surface profile containing affixed debris to a predetermined substrate outer surface profile by comparing a library of predetermined profiles to an actual substrate outer surface profile in real time.

Abstract: An absorption refrigeration and air conditioning device capable of controlling temperature and/or the humidity of enclosed spaces particularly useful in maritime applications and improving fuel economy of internal combustion engines is provided.

Abstract: The invention is concerned with the compounds of formula I or II: and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I or II as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

Abstract: Systems, methods, and computer-readable media are disclosed for universal anchor points for mobile robots. In one embodiment, an example mobile robot may include a chassis, a removable assembly comprising a support member, and a first anchor point coupled to the chassis. The first anchor point may be configured to anchor the support member to the chassis. The first anchor point may be configured to be coupled to support members of different diameters or widths.

Abstract: A wireless power system may have a wireless power transmitting device and wireless power receiving devices. The wireless power transmitting device has wireless power transmitting circuitry with coils to transmit wireless power to wireless power receiving devices. The wireless power receiving devices are placed on the wireless power transmitting device in an order. Batteries in the wireless power receiving devices are charged based at least partly on the order. Power allocation is based on utilization factor information such as information on a power draw associated with each of the power receiving devices. Measurement circuitry in the wireless power transmitting device is used to gather impedance images from the coils. Changes in the impedance images are used to temporarily halt power transmission. Power transmission is resumed depending on whether in-band communications are lost or are maintained.

Abstract: A driver assistance system is provided in a motor vehicle, which driver assistance system executes at least active transverse guidance interventions. The driver assistance system can be activated while decoupled from the activation of a longitudinal control system but can also be active both, with and without longitudinal control, and includes both a traffic jam assistance sub-function and a track guiding assistant sub-function. The two sub-functions can be jointly activated and deactivated by a single on-/off-button. The driver assistance system is characterized by a special combination of the sub-functions track guiding assistance and traffic jam assistance. They each take turns depending on the presence of conditions, which are defined differently for each sub-function.

Abstract: A system includes at least one hardware processor and a memory storing instructions that, when executed by the at least one hardware processor, cause the at least one hardware processor to perform operations including receiving an initiation message associated with a collaboration event between a first user and a second user, the collaboration event is initiated by the first user, determining a target device from a pool of computing devices associated with the second user based on usage history of each computing device in the pool of computing devices, initiating a collaboration session with the second user via the target device, and presenting collaborative content to the second user via the target device during the collaboration session.

Abstract: An authentication system for providing shared credential authentication includes a client information handling (IHS) system having a resource service application, and a mobile IHS having a shared authentication application. The shared authentication token indicates that an authenticated state between the client IHS and the mobile IHS exists. The resource service application receives a request to access the resource, and sends an authentication request to an authentication server to authorize access to the resource. The shared authentication application receives a query from the authentication server to verify a status of a shared authentication token, and, when the shared authentication token is valid, responds to the query that the shared authentication token is valid. The resource service application further receives a response to the authentication request, and grants access to the resource when the authentication token indicates that the shared authentication token is valid.

Abstract: An information handling system includes a processor that provides a USB-2 channel and a USB-3 channel to a device. The device provides the USB-2 and -3 channels to selected ports. Each port includes a USB-3 enable setting. When the USB-3 enable setting for each particular USB port is in a first state, the associated device USB-3 channel is active, and when the USB-3 enable setting for each particular USB port is in a second state, the associated device USB-3 channel is inactive. The USB-3 enable setting for at least one of the USB ports is placed into the second state to reduce electromagnetic interference between the associated USB-3 channel and an antenna.

Abstract: The present invention provides an embossed multi-ply tissue product that is visually pleasing and has improved physical attributes. For example, the inventive multi-ply tissue products have reduced stiffness, such as a GM Flexural Rigidity less than about 600 mg*cm, improved absorbency, such as a Residual Water (WResidual) value less than about 0.15 g, and improved wet resiliency, such as a Wet Elastic Strain Ratio greater than about 32 percent.

Abstract: For small, high-resolution, light-emitting diode (LED) displays, such as for a near-eye display in an artificial-reality headset, LEDs are spaced closely together. A backplane can be used to drive an array of LEDs in an LED display. A plurality of interconnects electrically couple the backplane with the array of LEDs. As spacing between LEDs becomes smaller than interconnect spacing, a thin-film circuit layer can be used to reduce a number or interconnects between the backplane and the array of LEDs, so that interconnect spacing can be larger than LED spacing. This can allow LEDs in the LED display to be more densely arranged while still allowing use of a silicon backplane with drive circuitry to control operation of the LEDs in the LED display.

Abstract: A digital-to-analog conversion system is provided. The digital-to-analog conversion system includes a digital-to-analog converter configured to receive a pre-distorted digital signal from a digital circuit, and to generate an analog signal based on the pre-distorted digital signal. Further, the digital-to-analog conversion system includes a feedback loop for providing a digital feedback signal to the digital circuit. The feedback loop includes an analog-to-digital converter configured to generate the digital feedback signal based on the analog signal, and wherein a sample rate of the analog-to-digital converter is lower than a sample rate of the digital-to-analog converter.