Patents by Inventor Daniel To

Daniel To has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AIR SANITIZING APPARATUS FOR INTERIOR OF VEHICLE AND METHOD OF SANITIZING AIR IN THE VEHICLE USING THE APPARATUS
    Publication number: 20200198445
    Abstract: An air sanitizing apparatus for a vehicle comprising: an ozone generator; a negative ion generator; and an ultraviolet radiation source. The air sanitizing apparatus further includes a rotating feature and a motor operably connected to the rotating feature, the rotating feature configured to move the air sanitizing apparatus along a track system. The air sanitizing apparatus can includes a first end portion; a second end portion; a middle portion disposed between the first end portion and the second end portion, the middle portion rotatable relative to the first end portion and the second end portion about an axis that extends through both the first end portion and the second end portion. The ozone generator, the negative ion generator, and the ultraviolet radiation source are all disposed at the middle portion.
    Type: Application
    Filed: December 20, 2018
    Publication date: June 25, 2020
    Applicant: Ford Global Technologies, LLC
    Inventors: Johnathan Andrew Line, Michael Kolich, Daniel Ferretti, Scott H. Dunham
  • AUTONOMOUS AGRICULTURAL SYSTEM USER INTERFACE INTERLOCK
    Publication number: 20200201502
    Abstract: A control system for an autonomous agricultural system includes a display configured to display at least one control function associated with at least one operation. The display is configured to output a first signal indicative of a first input. The control system includes a controller comprising a processor and a memory. The controller is communicatively coupled to the display and configured to receive the first signal indicative of the first input and to send a second signal to the display indicative of instructions to display a second control in an unlocked state. The display is configured to output a third signal to the controller indicative of the second input. The controller is configured to receive the third signal and to output a fourth signal indicative of instructions to control the at least one operation of the autonomous agricultural system.
    Type: Application
    Filed: January 15, 2020
    Publication date: June 25, 2020
    Inventors: Christopher Alan Foster, John Henry Posselius, Bret Todd Turpin, Daniel John Morwood, Brandon Chamberlain Adams, James Allen Bradford, Kim Richardson Barker
  • DENTAL BONE FOUNDATION GUIDE WITH BUR INSTRUMENT GUIDE FEATURES
    Publication number: 20200197126
    Abstract: An apparatus includes a first guide and a second guide. The first guide includes an arcuate horizontal body portion. A rear surface of the horizontal body portion is configured to closely mate with a front-facing bone structure of an alveolar arch of a patient. The second guide includes a body and a coupling member. The body defines a passageway that is configured to receive a bone reducing instrument. The coupling member is configured to mate with the horizontal body portion of the first guide. The body and the coupling member are configured to position the passageway along a second horizontal plane that is parallel with the first horizontal plane. The coupling member is configured to enable the second guide to relative to the first guide along the second horizontal plane and thereby guide the bone reducing instrument along the second horizontal plane.
    Type: Application
    Filed: December 5, 2019
    Publication date: June 25, 2020
    Inventor: Daniel R. Llop
  • ANTI-MESOTHELIN RADIOLABELLED SINGLE DOMAIN ANTIBODIES SUITABLE FOR THE IMAGING AND TREATMENT OF CANCERS
    Publication number: 20200197547
    Abstract: Mesothelin (MSLN) has been found to be overexpressed in several human malignancies: 100% of epithelial mesotheliomas, the majority of pancreatic and ovarian adenocarcinomas, more than 50% of lung adenocarcinomas and 34 to 67% of triple negative breast cancer (TNBC). The limited expression of mesothelin in normal human tissues and its overexpression in several aggressive human cancers make MSLN an attractive candidate for therapy. The objective of the inventors was to perform the nuclear imaging of TNBC xenografts with anti-MSLN single domain antibodies radiolabeled with 99mTc (99mTc-A1 and 99mTc-C6). They showed that 99mTc-A1 represent a good candidate for targeting mesothelin positive tumors. Accordingly, the present invention to an anti-mesothelin single domain antibody which is labelled with a radionuclide and its uses for imaging and/or treating cancer.
    Type: Application
    Filed: August 29, 2018
    Publication date: June 25, 2020
    Inventors: Alexis BROISAT, Catherine GHEZZI, Christopher MONTEMAGNO, Daniel FAGRET
  • METHOD AND APPARATUS FOR A SHAPE MEMORY IMPLANT
    Publication number: 20200197005
    Abstract: An apparatus for fixating bone includes an orthopedic implant. The orthopedic implant may be manufactured from a shape memory material such that the orthopedic implant is moveable between a natural shape and an insertion shape. The orthopedic implant defines at least a first cannulation therethrough adapted to deliver a bone augmentation material to the bone. The orthopedic implant implants into the bone in its insertion shape. After implantation of the orthopedic implant, the first cannulation facilitates delivery into the bone of a bone augmentation material that augments the bone. The orthopedic implant once implanted attempts to transition from its insertion shape to its natural shape such that the orthopedic implant fixates the bone.
    Type: Application
    Filed: December 19, 2018
    Publication date: June 25, 2020
    Applicant: Depuy Synthes Products, Inc.
    Inventor: Steffan Daniel
  • SPORTS EQUIPMENT COMPRISING SILICONE POLYCARBONATE ELASTOMER
    Publication number: 20200197755
    Abstract: A sports equipment article comprises a thermoplastic poly(carbonate-siloxane) elastomer.
    Type: Application
    Filed: May 16, 2018
    Publication date: June 25, 2020
    Inventors: Robert Russell Gallucci, Daniel Francis Lowery
  • COMPOUNDS, COMPOSITIONS, METHODS FOR TREATING DISEASES, AND METHODS FOR PREPARING COMPOUNDS
    Publication number: 20200199123
    Abstract: Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which can be used for treating, for example, certain diseases. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as head and neck squamous cell carcinoma (HNSCC), cancer, blood disorders, etc.). Additional embodiments provide synergistic combinations of a BCL2 inhibitor with an IRAK inhibiting compound, and methods of using same.
    Type: Application
    Filed: February 28, 2020
    Publication date: June 25, 2020
    Inventors: Daniel T. STARCZYNOWSKI, Craig J. THOMAS, Garrett RHYASEN, Katelyn MELGAR, Morgan MacKenzie WALKER, Jian-kang JIANG
  • ARTICLE OF FOOTWEAR
    Publication number: 20200196705
    Abstract: An article of footwear includes an upper formed of a base layer, a reinforcement layer, and an auxetic structure coupled to the reinforcement layer. The base layer includes an elastic material and is elastically deformable between a resting configuration and a stretched configuration. The base layer is configured to be stretched to a predetermined amount. The inelastic reinforcement layer is coupled to the base layer. The reinforcement layer is configured to delimit the stretch amount of the base layer when the base layer is in the stretched configuration.
    Type: Application
    Filed: December 17, 2019
    Publication date: June 25, 2020
    Inventors: Alan Toronjo, Daniel Lee, Roger Fan
  • DENTAL ABUTMENT CAP ASSEMBLY
    Publication number: 20200197134
    Abstract: An apparatus includes a dental prosthetic, a metallic insert, and a plastic cap member. The insert is configured to be bonded in an interior of the dental prosthetic. The insert defines a passageway. The of the insert is configured to receive a screw. The cap member is configured to be interposed between the insert and the interior of the dental prosthetic.
    Type: Application
    Filed: December 5, 2019
    Publication date: June 25, 2020
    Inventor: Daniel R. Llop
  • THREAT DETECTION PLATFORMS FOR DETECTING, CHARACTERIZING, AND REMEDIATING EMAIL-BASED THREATS IN REAL TIME
    Publication number: 20200204572
    Abstract: Conventional email filtering services are not suitable for recognizing sophisticated malicious emails, and therefore may allow sophisticated malicious emails to reach inboxes by mistake. Introduced here are threat detection platforms designed to take an integrative approach to detecting security threats. For example, after receiving input indicative of an approval from an individual to access past email received by employees of an enterprise, a threat detection platform can download past emails to build a machine learning (ML) model that understands the norms of communication with internal contacts (e.g., other employees) and/or external contacts (e.g., vendors). By applying the ML model to incoming email, the threat detection platform can identify security threats in real time in a targeted manner.
    Type: Application
    Filed: November 4, 2019
    Publication date: June 25, 2020
    Inventors: Sanjay Jeyakumar, Jeshua Alexis Bratman, Dmitry Chechik, Abhijit Bagri, Evan James Reiser, Sanny Xiao Yang Liao, Yu Zhou Lee, Carlos Daniel Gasperi, Kevin Lau, Kai Jing Jiang, Su Li Debbie Tan, Jeremy Kao, Cheng-Lin Yeh
  • COMBINATION THERAPY
    Publication number: 20200197403
    Abstract: Provided herein are methods of treating diseases, such as cancer, using a combination therapy. In certain embodiments, the methods comprise administering an effective amount of a phosphoinositide-3-kinase (PI3K) inhibitor and an effective amount of a PD-1 or PD-L1 inhibitor to a patient.
    Type: Application
    Filed: May 22, 2018
    Publication date: June 25, 2020
    Inventor: Daniel P. GOLD
  • USE OF POLYGLYCOLS TO CONTROL RHEOLOGY OF UNIT DOSE DETERGENT COMPOSITIONS
    Publication number: 20200199491
    Abstract: A method for maintaining a consistent, low viscosity profile of a unit dose detergent composition for enhanced hydration and dissolution upon hydration including the steps of: (1) A method for maintaining a consistent, low viscosity profile of a unit dose detergent composition for enhanced hydration and dissolution upon hydration including the steps of: (1) providing the detergent composition including: about 2.5 to about 15 wt. % of a polyglycol, an alkyl-ether sulfate, a linear alkylbenzene sulfonate, and a fatty alcohol ethoxylate, wherein the alkyl-ether sulfate, linear alkylbenzene sulfonate, and fatty alcohol ethoxylate are collectively present in an amount of 30 to 70 wt. %, by weight of the detergent composition; and (2) encapsulating the detergent composition in a pouch made of a water soluble film.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 25, 2020
    Applicant: Henkel IP & Holding GmbH
    Inventors: Daniel T. Piorkowski, David S. Stott, II
  • MICROMECHANICAL PRESSURE SENSOR SYSTEM AND METHOD FOR MANUFACTURING A MICROMECHANICAL PRESSURE SENSOR SYSTEM
    Publication number: 20200200634
    Abstract: A micromechanical pressure sensor system, including: a substrate; a pressure sensor component connected to the substrate; and an essentially hollow frustum-shaped sleeve structure, which is connected to the substrate, which surrounds the pressure sensor component at least laterally and which has an opening at a side of the sleeve structure facing away from the substrate.
    Type: Application
    Filed: May 17, 2018
    Publication date: June 25, 2020
    Inventors: Uwe Schiller, Daniel Haug, Lars Sodan, Michael Knauss, Robert Kuells, Sebastian Schuler-Watkins
  • MANY-TO-MANY SYMMETRIC CRYPTOGRAPHIC SYSTEM AND METHOD
    Publication number: 20200204366
    Abstract: Many-to-many cryptographic systems and methods are disclosed, including numerous industry applications. Embodiments of the present invention can generate and regenerate the same symmetric key from a random token. The many-to-many cryptographic systems and methods include two or more cryptographic modules being in communication with each other and may be located at different physical locations. The cryptographic modules are configured to encrypt and/or decrypt data received from other cryptographic modules and to provide encrypted and/or decrypted data to other cryptographic modules. Each cryptographic module includes a key generator configured to use two or more inputs to reproducibly generate the symmetric key and a cryptographic engine configured to use the symmetric key for encrypting and decrypting data. Corresponding methods are also provided.
    Type: Application
    Filed: February 26, 2018
    Publication date: June 25, 2020
    Inventors: Glen Arthur HENDERSON, Brent Eric Nordin, Daniel Marcel Joseph Seguin, Prateek Srivastava, Ian Hugh Curry
  • Doubles End-Effector for Robotic Harvesting
    Publication number: 20200196528
    Abstract: An example system includes a nozzle having an inlet: an outlet mechanism disposed longitudinally adjacent to the nozzle; a conduit longitudinally adjacent to the outlet mechanism where the conduit includes a distal chamber, a middle chamber, and a proximal chamber, that; are longitudinally disposed along a length of the conduit; a partition block configured to move between (i) a first position at which the partition block: is disposed laterally adjacent to the middle chamber, such that the partition block is offset from a longitudinal axis of the conduit, and (ii) a second position at which the partition block resides in the middle chamber between the distal chamber and the proximal chamber; and a deceleration structure disposed at a proximal, end of the conduit and bounding the proximal chamber, where the deceleration structure is configured to decelerate fruit feat has traversed the conduit.
    Type: Application
    Filed: September 5, 2018
    Publication date: June 25, 2020
    Inventors: Curt Salisbury, Daniel C. Steere, Michael Eriksen, Cedric Schwab
  • VEHICLE NAVIGATION SYSTEM
    Publication number: 20200201359
    Abstract: A system and method that function to generate an updated vehicle state based on a previous vehicle state and a set of sensor measurements. The previous vehicle state can be selected from a set of redundant prior vehicle state candidates. The system and method can optionally detect and correct for sensor measurement faults or failures, prior to updating the vehicle state.
    Type: Application
    Filed: December 19, 2019
    Publication date: June 25, 2020
    Inventors: Michael Burghardt, JoeBen Bevirt, Daniel Burghardt, Kevin O'Connor, Tianyu Gu, Kyle Cordes, Steve Waller
  • CATHETER WITH FLEX CIRCUIT DISTAL ASSEMBLY
    Publication number: 20200197082
    Abstract: An electrophysiology catheter has an elongated catheter shaft and a distal assembly with a flex circuit and a support member on which the flex circuit is supported in a generally cylindrical form. The support member has a post extending longitudinally through the cylindrical form of the flex circuit which delivers irrigation fluid into the cylindrical form. The post can be configured to define multiple irrigation chambers within the distal assembly. One or more flow directors movable in the post selectively direct irrigation fluid within the distal assembly. Apertures in the flex circuit allow the irrigation fluid to exit to outside the distal assembly.
    Type: Application
    Filed: December 20, 2018
    Publication date: June 25, 2020
    Inventors: Steven A. Daniel, Daniele Ghidoli
  • PEPTIDES AND COMBINATION OF PEPTIDES OF NON-CANONICAL ORIGIN FOR USE IN IMMUNOTHERAPY AGAINST DIFFERENT TYPES OF CANCERS
    Publication number: 20200197441
    Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
    Type: Application
    Filed: February 14, 2020
    Publication date: June 25, 2020
    Inventors: Heiko SCHUSTER, Franziska HOFFGAARD, Jens FRITSCHE, Oliver SCHOOR, Toni WEINSCHENK, Daniel Johannes KOWALEWSKI, Chih-Chiang TSOU
  • CHILD-RESISTANT CONTAINER HAVING CAP RETAINER FEATURES
    Publication number: 20200198855
    Abstract: A container body has a neck defining an opening with an axis. The neck includes a projection that projects radially away from the axis. A cap includes a wall that defines at least part of an exterior of the cap. The wall includes an aperture extending therethrough. The cap is removably attached to the neck and supported for movement on the neck between a first position and a second position. The wall is resiliently flexible for radial movement between a retained position and an unretained position with respect to the neck. In the retained position the projection retains the cap in the first position. The wall, in the unretained position, allows movement of the cap from the first position toward the second position.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 25, 2020
    Applicant: HENKEL IP & HOLDING GmbH
    Inventors: Daniel Peter Sterling, Keith Colacioppo
  • PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST LEUKEMIAS AND OTHER CANCERS
    Publication number: 20200199193
    Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
    Type: Application
    Filed: February 18, 2020
    Publication date: June 25, 2020
    Inventors: Juliane Sarah WALZ, Daniel Johannes KOWALEWSKI, Markus LOEFFLER, Moreno DI MARCO, Nico TRAUTWEIN, Annika NELDE, Stefan STEVANOVIC, Hans-Georg RAMMENSEE, Sebastian HAEN