Abstract: The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for establishing a controlled flow or access passage between body lumens.

Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for establishing a controlled flow or access passage between body lumens.

Abstract: The present disclosure relates generally to the field of medical devices and medical device delivery. In particular, the present disclosure relates to medical devices and delivery systems for positioning and delivering medical devices with an unsupported structure, for example, within a distant and/or tortuous portion of body lumen. For example, a delivery system may position a supported structure of a medical device within a proximal portion of a body lumen and an unsupported structure of the medical device within a distal portion of the body lumen. Examples include delivery systems within an unsupported structure of a medical device to be delivered, wherein a number of balloons are arranged un-inflated within an unsupported structure, with a distal balloon removably attached to a distal portion of the unsupported structure, and the balloons are inflatable in series to deploy the unsupported structure linearly from a distal end of the delivery system.

Abstract: A medical stent including a tubular scaffold is disclosed. The tubular scaffold is formed from a single wire extending helically from a first end to a second end along a central longitudinal axis such that the single wire forms a plurality of helical windings around the central longitudinal axis. A polymeric covering is disposed on the tubular scaffold and spans gaps between adjacent helical windings of the tubular scaffold. The stent includes a plurality of longitudinal reinforcing strips extending along the tubular scaffold parallel to the central longitudinal axis. The reinforcing strips are configured to restrict elongation of the stent by less than 5% when the stent shifts between a radially collapsed delivery configuration and a radially expanded deployed configuration.

Abstract: An endoprosthesis includes a body portion extending from a first end to a second end along a central longitudinal axis. The body portion is formed from a single wire extending from the first end to the second end and forming a plurality of circumferential segments extending non-helically around the axis. The plurality of circumferential segments includes a first end circumferential segment forming the first end, a second end circumferential segment forming the second end, and at least one medial circumferential segment disposed between the first and second end circumferential segments. Each circumferential segment includes an undulating arrangement of first struts and second struts defining peaks and valleys, the first and second struts being disposed at first and second angles, respectively, relative to the axis in a side view of the body portion. Peaks and valleys of adjacent circumferential segments may be axially aligned with each other parallel to the axis.

Abstract: A stent comprises a tubular scaffold formed of a single filament that is woven to define a plurality of open cells; wherein the plurality of open cells includes a helical row of large open cells, a first helical row of small open cells, and a second helical row of small open cells; and a reinforcing filament extending substantially longitudinally along the tubular scaffold.

Abstract: An endoprosthesis includes a body portion extending axially from a first end to a second end. The body portion is formed from a single wire extending from the first end to the second end. The single wire forms a plurality of circumferential rings. Each circumferential ring comprises an undulating arrangement of struts defining peaks and valleys. At least one circumferential ring may include a loop formed at each peak or at each valley of the at least one circumferential ring. A loop may be formed at each peak or at each valley of each circumferential ring. A loop may be formed at each peak and at each valley of each circumferential ring.

Abstract: A stent is disclosed. The stent includes a tubular scaffold extending from a first end to a second end in which the tubular scaffold is formed of a single filament shaped to form a plurality of open cells throughout the tubular scaffold. Each of the open cells may be formed as a parallelogram shape defined by two pairs of opposing linear sections of the filament and pseudo hooked sections of the filament at each apex of the plurality of open cells, wherein each of apices of the plurality of open cells includes a pseudo hooked region in which first and second bends of the single filament overlap one another. The open cells may include first and second helical rows of small open cells, and a first helical row of large open cells positioned therebetween.

Abstract: An endoprosthesis, such as a stent, includes a body portion extending axially from a first end to a second end along a central longitudinal axis; wherein the body portion is formed from a single wire extending from the first end to the second end and where the single wire forms a plurality of circumferential segments extending non-helically around the central longitudinal axis; and a reinforcing filament extending substantially longitudinally along the body portion.

Abstract: A stent is disclosed. The stent includes a tubular scaffold extending from a first end to a second end in which the tubular scaffolding is formed of a single filament woven to form a plurality of open cells throughout the tubular scaffold. Each of the open cells may be formed as a parallelogram shape defined by two pairs of opposing linear sections of the filament and hooked sections of the filament at each apex of the plurality of open cells, wherein each of apices of the plurality of open cells includes a hooked region in which the single filament is intertwined with itself and changes weaving direction. The open cells may include first and second helical rows of small open cells, and a first helical row of large open cells positioned therebetween.

Abstract: An illustrative stent may include an expandable framework with a proximal end, a distal end, and a length extending therebetween. The expandable framework of the stent may include a single filament forming one or more undulating pattern sections and one or more knitted sections. The expandable framework of the stent may further include one or more of a coating and a covering.

Abstract: A delivery system for delivering an implant to a body lumen of a patient. The delivery system may include a hub, an elongate shaft coupled with the hub, and a thread for securing the implant to the elongate shaft. The elongate shaft may include a proximal portion at least partially defining a first lumen and a second lumen, a distal portion at least partially defining the first lumen, and a side port in the proximal portion and distal of the hub. The side port may be in communication with the first lumen. The thread may include a distal portion configured to wrap around the distal portion of the elongate shaft and/or the implant and a proximal portion configured to extend through the second lumen. The delivery system may be configured to deliver the implant to a target location in a lumen of a biliary tract of the patient.

Abstract: An endoprosthesis configured to shift between a collapsed configuration and an expanded configuration may include a tubular scaffold formed from a single filament knitted about a central longitudinal axis and defining a length from a proximal end to a distal end, the tubular scaffold including a plurality of rows of loops and a plurality of rows of rungs arranged around the central longitudinal axis in an alternating fashion; and a polymeric covering extending along the tubular scaffold. Each row of loops and each row of rungs extends longitudinally along the tubular scaffold between the proximal end and the distal end. The tubular scaffold includes a first cutout region extending along a majority of the length of the tubular scaffold and a second cutout region extending along a majority of the length of the tubular scaffold. The polymeric covering is uninterrupted along the first cutout region and the second cutout region.

Abstract: An endoprosthesis configured to shift between a collapsed configuration and an expanded configuration may include a tubular scaffold formed from a single filament knitted about a central longitudinal axis and defining a length from a proximal end to a distal end, the tubular scaffold including a plurality of rows of loops and a plurality of rows of rungs arranged around the central longitudinal axis in an alternating fashion; and a polymeric covering extending along the tubular scaffold. Each row of loops and each row of rungs extends longitudinally along the tubular scaffold between the proximal end and the distal end. The tubular scaffold includes a first cutout region extending along a majority of the length of the tubular scaffold and a second cutout region extending along a majority of the length of the tubular scaffold. The polymeric covering is uninterrupted along the first cutout region and the second cutout region.

Abstract: The present disclosure relates generally to stents, systems, and methods for anchoring devices within a body lumen by cooperation between the device and the body musculature. A device comprising an elongate tubular member may be deployed within a body lumen, where the body lumen includes a sphincter that regulates flow through the body lumen. The elongate tubular member includes a sleeve formed from a flexible membrane and one or more stents disposed at either or both ends of the sleeve. In some embodiments, the stents may be treatment stents configured to treat a portion of the body lumen. The elongate tubular member may be deployed within the body lumen such that the flexible membrane aligns with and moves in coordination with the sphincter, thereby increasing retention forces acting upon the elongate tubular member when the sphincter is closed to minimize treatment stent migration.

Abstract: The present disclosure relates generally to stents, systems, and methods for anchoring devices within a body lumen by cooperation between the device and the body musculature. A device comprising an elongate tubular member may be deployed within a body lumen, where the body lumen includes a sphincter that regulates flow through the body lumen. The elongate tubular member includes a sleeve formed from a flexible membrane and one or more stents disposed at either or both ends of the sleeve. In some embodiments, the stents may be treatment stents configured to treat a portion of the body lumen. The elongate tubular member may be deployed within the body lumen such that the flexible membrane aligns with and moves in coordination with the sphincter, thereby increasing retention forces acting upon the elongate tubular member when the sphincter is closed to minimize treatment stent migration.

Abstract: An illustrative stent includes an elongated tubular member comprising at least one strut forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating may be disposed on the elongated tubular member and spanning at least some of the plurality of cells. One or more magnetic components may be disposed on or within the coating.

Abstract: A medical system including a tube defining a lumen, a porous body connected to a distal end of the tube to be advanced to a target site within a subject. The porous body defines a plurality of openings, the plurality of openings are in fluid connection with the lumen, the porous body includes a first material and a second material, and the second material elutes from the porous body in the subject.

Abstract: An illustrative endoluminal implant having an elongated tubular member. The elongate tubular member having a proximal stent, a distal stent and an interconnecting sleeve. The proximal stent tapers from a first outer diameter adjacent the proximal end region to a second smaller outer diameter adjacent the distal end region. The distal stent has an outer diameter less than the first outer diameter of the proximal stent. The interconnecting sleeve is collapsible in response to an applied radial force such that the sleeve is positionable across a natural valve or sphincter.