Abstract: This disclosure addresses inaccuracies in stent deployment due to the frictional forces experienced by a co-axial delivery system within an endoscope. The disclosed stent delivery systems incorporate a pull thread assembly to retract a stent retention tube to release a self-expanding stent. The disclosed systems and method may include additional components to maintain the integrity of the pull thread assembly. The stent delivery system may include a floating tubular bumper and/or eyelets to contain the pull threads of the pull thread assembly along an exterior of an inner shaft of the stent delivery system. These configurations reduce friction between the components of the stent delivery system and the working channel of an endoscope, enabling more precise stent deployment by preventing inadvertent movement and premature release.

Abstract: A stent may include a tubular body extending from a proximal end to a distal end and defining a lumen therethrough. The stent may comprise a scaffold structure formed from one or more filaments extending between the proximal and distal ends, and a polymeric coating disposed along at least a portion of the scaffold structure. A distal region of the tubular body includes a plurality of openings through the polymeric coating while maintaining the polymeric coating on the one or more filaments. The polymeric coating may comprise silicone and is configured to increase radial force of the tubular body.

Abstract: A system for maintaining patency of a body lumen may include a first endoprosthesis configured to shift from a straightened configuration to a helical configuration defining a plurality of loops, and a second endoprosthesis configured to shift from a radially collapsed configuration toward a radially expanded configuration. The plurality of loops defines a passage having an inner diameter. At least a portion of the second endoprosthesis is disposed within the passage in the radially expanded configuration. A method of maintaining patency of a body lumen may include advancing a first endoprosthesis into a first body lumen in a straightened configuration, deploying the first endoprosthesis within the first body lumen in a helical configuration defining a plurality of loops, advancing a second endoprosthesis into the first body lumen in a radially collapsed configuration, and shifting the second endoprosthesis to a radially expanded configuration within the plurality of loops.

Abstract: A stent system includes a self-expanding endoprosthesis and a stent delivery system including an elongate shaft having an inflatable balloon disposed proximate a distal end, and an endoprosthesis retention element disposed around the self-expanding endoprosthesis and the inflatable balloon. The retention element is configured to constrain the endoprosthesis in a radially collapsed configuration. The retention element is configured to fracture upon inflation of the balloon. The endoprosthesis is configured to exert a first radially outward force in the radially collapsed configuration. The retention element is configured to fracture when a second radially outward force greater than the first is applied to the retention element. The retention element includes a tubular sleeve disposed radially outward of and in intimate contact with the endoprosthesis, wherein the tubular sleeve is configured to break apart when the balloon is shifted toward the inflated configuration.

Abstract: This disclosure addresses deployment accuracy challenges in co-axial stent delivery systems by incorporating various ancillary devices: a tubular curved track that constrains catheter movement, a handle clamp that secures the proximal handle position, and/or a stiffening support shaft that can be inserted into a lumen of the catheter. The tubular curved track features a loop body with a channel along its length to receive and stabilize the catheter's proximal portion. The handle clamp includes a cavity and clamping mechanism to secure the proximal handle to a support structure. The stiffening support shaft can be inserted to various depths to prevent unwanted catheter movement. These ancillary devices can be used individually or in combination to enhance stent deployment accuracy by reducing unintended movements during the deployment procedure.

Abstract: Medical systems for positioning a stent along a tissue pathway are disclosed. A system includes an inner shaft having a lumen, a proximal end coupled to the handle and a distal end coupled to a tip member. The system also includes an outer shaft having a proximal end region and a lumen, wherein at least a portion of the inner shaft extends within the lumen of the outer shaft. The system also includes a stent positioned between an inner surface of the outer shaft and an outer surface of the inner shaft. Further, the tip member includes a first engagement member configured to engage and anchor the tip member to a tissue of the tissue pathway before the stent engages the tissue pathway.

Abstract: The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for establishing a controlled flow or access passage between body lumens.

Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for establishing a controlled flow or access passage between body lumens.

Abstract: The present disclosure relates generally to the field of medical devices and medical device delivery. In particular, the present disclosure relates to medical devices and delivery systems for positioning and delivering medical devices with an unsupported structure, for example, within a distant and/or tortuous portion of body lumen. For example, a delivery system may position a supported structure of a medical device within a proximal portion of a body lumen and an unsupported structure of the medical device within a distal portion of the body lumen. Examples include delivery systems within an unsupported structure of a medical device to be delivered, wherein a number of balloons are arranged un-inflated within an unsupported structure, with a distal balloon removably attached to a distal portion of the unsupported structure, and the balloons are inflatable in series to deploy the unsupported structure linearly from a distal end of the delivery system.

Abstract: A medical stent including a tubular scaffold is disclosed. The tubular scaffold is formed from a single wire extending helically from a first end to a second end along a central longitudinal axis such that the single wire forms a plurality of helical windings around the central longitudinal axis. A polymeric covering is disposed on the tubular scaffold and spans gaps between adjacent helical windings of the tubular scaffold. The stent includes a plurality of longitudinal reinforcing strips extending along the tubular scaffold parallel to the central longitudinal axis. The reinforcing strips are configured to restrict elongation of the stent by less than 5% when the stent shifts between a radially collapsed delivery configuration and a radially expanded deployed configuration.

Abstract: An endoprosthesis includes a body portion extending from a first end to a second end along a central longitudinal axis. The body portion is formed from a single wire extending from the first end to the second end and forming a plurality of circumferential segments extending non-helically around the axis. The plurality of circumferential segments includes a first end circumferential segment forming the first end, a second end circumferential segment forming the second end, and at least one medial circumferential segment disposed between the first and second end circumferential segments. Each circumferential segment includes an undulating arrangement of first struts and second struts defining peaks and valleys, the first and second struts being disposed at first and second angles, respectively, relative to the axis in a side view of the body portion. Peaks and valleys of adjacent circumferential segments may be axially aligned with each other parallel to the axis.

Abstract: A stent comprises a tubular scaffold formed of a single filament that is woven to define a plurality of open cells; wherein the plurality of open cells includes a helical row of large open cells, a first helical row of small open cells, and a second helical row of small open cells; and a reinforcing filament extending substantially longitudinally along the tubular scaffold.

Abstract: An endoprosthesis includes a body portion extending axially from a first end to a second end. The body portion is formed from a single wire extending from the first end to the second end. The single wire forms a plurality of circumferential rings. Each circumferential ring comprises an undulating arrangement of struts defining peaks and valleys. At least one circumferential ring may include a loop formed at each peak or at each valley of the at least one circumferential ring. A loop may be formed at each peak or at each valley of each circumferential ring. A loop may be formed at each peak and at each valley of each circumferential ring.

Abstract: A stent is disclosed. The stent includes a tubular scaffold extending from a first end to a second end in which the tubular scaffold is formed of a single filament shaped to form a plurality of open cells throughout the tubular scaffold. Each of the open cells may be formed as a parallelogram shape defined by two pairs of opposing linear sections of the filament and pseudo hooked sections of the filament at each apex of the plurality of open cells, wherein each of apices of the plurality of open cells includes a pseudo hooked region in which first and second bends of the single filament overlap one another. The open cells may include first and second helical rows of small open cells, and a first helical row of large open cells positioned therebetween.

Abstract: An endoprosthesis, such as a stent, includes a body portion extending axially from a first end to a second end along a central longitudinal axis; wherein the body portion is formed from a single wire extending from the first end to the second end and where the single wire forms a plurality of circumferential segments extending non-helically around the central longitudinal axis; and a reinforcing filament extending substantially longitudinally along the body portion.

Abstract: A stent is disclosed. The stent includes a tubular scaffold extending from a first end to a second end in which the tubular scaffolding is formed of a single filament woven to form a plurality of open cells throughout the tubular scaffold. Each of the open cells may be formed as a parallelogram shape defined by two pairs of opposing linear sections of the filament and hooked sections of the filament at each apex of the plurality of open cells, wherein each of apices of the plurality of open cells includes a hooked region in which the single filament is intertwined with itself and changes weaving direction. The open cells may include first and second helical rows of small open cells, and a first helical row of large open cells positioned therebetween.

Abstract: An illustrative stent may include an expandable framework with a proximal end, a distal end, and a length extending therebetween. The expandable framework of the stent may include a single filament forming one or more undulating pattern sections and one or more knitted sections. The expandable framework of the stent may further include one or more of a coating and a covering.

Abstract: A delivery system for delivering an implant to a body lumen of a patient. The delivery system may include a hub, an elongate shaft coupled with the hub, and a thread for securing the implant to the elongate shaft. The elongate shaft may include a proximal portion at least partially defining a first lumen and a second lumen, a distal portion at least partially defining the first lumen, and a side port in the proximal portion and distal of the hub. The side port may be in communication with the first lumen. The thread may include a distal portion configured to wrap around the distal portion of the elongate shaft and/or the implant and a proximal portion configured to extend through the second lumen. The delivery system may be configured to deliver the implant to a target location in a lumen of a biliary tract of the patient.

Abstract: An endoprosthesis configured to shift between a collapsed configuration and an expanded configuration may include a tubular scaffold formed from a single filament knitted about a central longitudinal axis and defining a length from a proximal end to a distal end, the tubular scaffold including a plurality of rows of loops and a plurality of rows of rungs arranged around the central longitudinal axis in an alternating fashion; and a polymeric covering extending along the tubular scaffold. Each row of loops and each row of rungs extends longitudinally along the tubular scaffold between the proximal end and the distal end. The tubular scaffold includes a first cutout region extending along a majority of the length of the tubular scaffold and a second cutout region extending along a majority of the length of the tubular scaffold. The polymeric covering is uninterrupted along the first cutout region and the second cutout region.