Patents by Inventor Daniel V. Brown

Daniel V. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11666253
    Abstract: Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: June 6, 2023
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventors: Juergen J. Zach, Daniel V. Brown
  • Patent number: 11638542
    Abstract: Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: May 2, 2023
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventors: Juergen J. Zach, Daniel V. Brown
  • Patent number: 11445944
    Abstract: Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: September 20, 2022
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventors: Juergen J. Zach, Daniel V. Brown
  • Publication number: 20200268323
    Abstract: Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.
    Type: Application
    Filed: February 20, 2020
    Publication date: August 27, 2020
    Inventors: Juergen J. Zach, Daniel V. Brown
  • Publication number: 20200268290
    Abstract: Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.
    Type: Application
    Filed: February 20, 2020
    Publication date: August 27, 2020
    Inventors: Juergen J. Zach, Daniel V. Brown
  • Publication number: 20180348193
    Abstract: Systems and methods employ a test sensor that includes an identification feature, such as a resistive element or other detectable circuit element, which allows a measurement device to interrogate the test sensor and to determine whether the correct test sensor type is being used to collect a fluid sample. For example, some embodiments employ test sensors that a measurement device can identify according to a response received from the test sensors when the measurement device applies an electrical signal to the test sensors. By facilitating identification of a test sensor, embodiments help ensure that the desired test type, calibration codes, and/or assay sequence are applied to the fluid sample collected by the test sensor.
    Type: Application
    Filed: August 17, 2015
    Publication date: December 6, 2018
    Inventors: Daniel V. Brown, Matthew Odom, Jeffery S. Reynolds
  • Patent number: 8480868
    Abstract: A method for distinguishing between types of electrochemical test sensors in a meter is disclosed. The method comprises the acts of providing an electrochemical test sensor comprising an enzyme and a chemical additive, contacting the test sensor to the meter to form an electrical connection, applying a potential having a magnitude sufficient to initiate a redox reaction of the chemical additive, and determining which type of electrochemical test sensor is being used based on whether a predetermined signal has been generated after the potential has been applied. The meter is adapted to determine an analyte concentration in a fluid sample.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: July 9, 2013
    Assignee: Bayer HealthCare LLC
    Inventor: Daniel V. Brown
  • Patent number: 8343332
    Abstract: An electrochemical test sensor for detecting the concentration of an analyte in a sample. The electrochemical test sensor comprises a base that provides a flow path for the fluid test sample having a counter electrode and a working electrode on its surface in electrical communication with a detector of electrical current. The electrochemical test sensor further includes a reagent layer directly located on the surface of the working electrode. The reagent layer includes an enzyme that is adapted to react with the analyte. The electrochemical test sensor further comprises a lid adapted to mate with the base and to assist in forming a capillary space with an opening for the introduction of the sample thereto. The capillary space is formed with a three-dimensional portion of the lid.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: January 1, 2013
    Assignee: Bayer HealthCare LLC
    Inventor: Daniel V. Brown
  • Publication number: 20120228156
    Abstract: A method for distinguishing between types of electrochemical test sensors in a meter is disclosed. The method comprises the acts of providing an electrochemical test sensor comprising an enzyme and a chemical additive, contacting the test sensor to the meter to form an electrical connection, applying a potential having a magnitude sufficient to initiate a redox reaction of the chemical additive, and determining which type of electrochemical test sensor is being used based on whether a predetermined signal has been generated after the potential has been applied. The meter is adapted to determine an analyte concentration in a fluid sample.
    Type: Application
    Filed: May 24, 2012
    Publication date: September 13, 2012
    Applicant: Bayer HealthCare LLC
    Inventor: Daniel V. Brown
  • Patent number: 8211292
    Abstract: A method for distinguishing between types of electrochemical test sensors in a meter is disclosed. The method comprises the acts of providing an electrochemical test sensor comprising an enzyme and a chemical additive, contacting the test sensor to the meter to form an electrical connection, applying a potential having a magnitude sufficient to initiate a redox reaction of the chemical additive, and determining which type of electrochemical test sensor is being used based on whether a predetermined signal has been generated after the potential has been applied. The meter is adapted to determine an analyte concentration in a fluid sample.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: July 3, 2012
    Assignee: Bayer HealthCare LLC
    Inventor: Daniel V. Brown
  • Publication number: 20110247944
    Abstract: An electrochemical test sensor for detecting the concentration of an analyte in a sample. The electrochemical test sensor comprises a base that provides a flow path for the fluid test sample having a counter electrode and a working electrode on its surface in electrical communication with a detector of electrical current. The electrochemical test sensor further includes a reagent layer directly located on the surface of the working electrode. The reagent layer includes an enzyme that is adapted to react with the analyte. The electrochemical test sensor further comprises a lid adapted to mate with the base and to assist in forming a capillary space with an opening for the introduction of the sample thereto. The capillary space is formed with a three-dimensional portion of the lid.
    Type: Application
    Filed: June 16, 2011
    Publication date: October 13, 2011
    Applicant: BAYER HEALTHCARE LLC
    Inventor: Daniel V. Brown
  • Patent number: 7993512
    Abstract: An electrochemical test sensor for detecting the concentration of an analyte in a sample. The electrochemical test sensor comprises a base that provides a flow path for the fluid test sample having a counter electrode and a working electrode on its surface in electrical communication with a detector of electrical current. The electrochemical test sensor further includes a reagent layer directly located on the surface of the working electrode. The reagent layer includes an enzyme that is adapted to react with the analyte. The electrochemical test sensor further comprises a lid adapted to mate with the base and to assist in forming a capillary space with an opening for the introduction of the sample thereto. The capillary space is formed with a three-dimensional portion of the lid.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: August 9, 2011
    Assignee: Bayer HealthCare, LLC
    Inventor: Daniel V. Brown
  • Patent number: 7955698
    Abstract: A fiber-based acoustic treatment material is provided. The material includes between about 3% and about 25% by weight of fibrillated microfibers, between about 20% and about 75% by weight of reinforcement microfibers, and between about 15% and about 60% by weight of a binder. Methods of making the material are also provided.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: June 7, 2011
    Assignee: Honeywell International Inc.
    Inventors: James F. Stevenson, Jeff M. Mendoza, Daniel V. Brown, Martin C. Baker, Lee Poandl
  • Patent number: 7945394
    Abstract: A method of detecting incomplete filling of an electrochemical biosensor by collecting a series of electrical current values when a constant electrical potential is applied across the working and counter electrodes during a preliminary burn period. The slope of a line determined by linear regression based on the series of current values is used to determine whether or not the biosensor is incompletely filled. If the line has a positive slope, the biosensor is reported to be under filled. If the slope is not positive, the correlation coefficient of the current values is used as a supplemental test to indicate whether or not the biosensor is incompletely filled.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: May 17, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Daniel V. Brown, Christina Blaschke
  • Publication number: 20100090153
    Abstract: A fiber-based acoustic treatment material is provided. The material includes between about 3% and about 25% by weight of fibrillated microfibers, between about 20% and about 75% by weight of reinforcement microfibers, and between about 15% and about 60% by weight of a binder.
    Type: Application
    Filed: November 15, 2006
    Publication date: April 15, 2010
    Inventors: James F. Stevenson, Jeff M. Mendoza, Daniel V. Brown, Martin C. Baker, Lee Poandl
  • Patent number: 7543481
    Abstract: A sensor for analyzing a fluid sample has a sample cavity for accepting sample fluid. At least one test region is disposed along the sample cavity, and at least one vent fulfills the dual function of venting the sample cavity and guiding the sample fluid in the sample cavity via appropriate location and geometry of at least one sample guide edge.
    Type: Grant
    Filed: February 4, 2005
    Date of Patent: June 9, 2009
    Assignee: Bayer Healthcare, LLC
    Inventors: Christina Blaschke, Daniel V. Brown, Sung-Kwon Jung
  • Publication number: 20090050491
    Abstract: A method for distinguishing between types of electrochemical test sensors in a meter is disclosed. The method comprises the acts of providing an electrochemical test sensor comprising an enzyme and a chemical additive, contacting the test sensor to the meter to form an electrical connection, applying a potential having a magnitude sufficient to initiate a redox reaction of the chemical additive, and determining which type of electrochemical test sensor is being used based on whether a predetermined signal has been generated after the potential has been applied. The meter is adapted to determine an analyte concentration in a fluid sample.
    Type: Application
    Filed: August 4, 2006
    Publication date: February 26, 2009
    Inventor: Daniel V. Brown
  • Publication number: 20080268485
    Abstract: This invention relates to an iconic display of pre-event or post-event iconic markers for a meter and a method for marking an analyte concentration with a pre-event or post-event iconic marker. The meter includes at least one segment on a display adapted to show a pre-event or post-event iconic marker. The user can interact with the meter via a button on the meter. The button allows the user to scroll from pre-event, post-event, and neither iconic marker, and it also allows the user to select one or neither of the iconic markers. A memory device located within the meter stores the analyte concentration with the corresponding pre-event, post-event, or neither iconic marker.
    Type: Application
    Filed: February 21, 2006
    Publication date: October 30, 2008
    Inventors: Julianne M. Guarino, Dijia Huang, Daniel V. Brown, Lawrence J. Burns
  • Patent number: 7367424
    Abstract: A muffler system is provided for use with an auxiliary power unit. In one embodiment, and by way of example only, the system includes an outer can, an annular baffle, and a tube. The outer can has a sidewall including a forward end, an aft end, and a cavity extending therebetween. The sidewall is disposed about a first longitudinal axis, and the cavity has a first cross-sectional area and a smaller second cross-sectional area. The annular baffle is coupled to and extends radially inward from the outer can sidewall and has an opening that is disposed about a second longitudinal axis that is non-coincident with the first longitudinal axis. The tube extends through the annular baffle opening and is spaced apart from the annular baffle to define a radial gap therebetween, comprises acoustic material, and has a length and a substantially uniform cross-sectional area along the length.
    Type: Grant
    Filed: August 5, 2005
    Date of Patent: May 6, 2008
    Assignee: Honeywell International, Inc.
    Inventors: Daniel V. Brown, Kyle D. Asplund, Joseph W. Michalski, Jr.
  • Publication number: 20080011616
    Abstract: An electrochemical test sensor for detecting the concentration of an analyte in a sample. The electrochemical test sensor comprises a base that provides a flow path for the fluid test sample having a counter electrode and a working electrode on its surface in electrical communication with a detector of electrical current. The electrochemical test sensor further includes a reagent layer directly located on the surface of the working electrode. The reagent layer includes an enzyme that is adapted to react with the analyte. The electrochemical test sensor further comprises a lid adapted to mate with the base and to assist in forming a capillary space with an opening for the introduction of the sample thereto. The capillary space is formed with a three-dimensional portion of the lid.
    Type: Application
    Filed: July 5, 2007
    Publication date: January 17, 2008
    Inventor: Daniel V. Brown