Patents by Inventor Daniel V. Palanker

Daniel V. Palanker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12102565
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Grant
    Filed: June 13, 2022
    Date of Patent: October 1, 2024
    Assignee: AMO Development, LLC
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Patent number: 12097145
    Abstract: A device for delivery of a precise amount of pharmaceutical fluid to the eye is provided. The device includes an ampoule for storing a liquid and an aperture through which the liquid is discharged. The device further includes a vibrating membrane that includes a needle which protrudes from the membrane and extends to the aperture to form a needle valve. The needle valve provides hermetic closure of the aperture to enable preservative-free storage of the pharmaceutical fluid in the device. The system further includes an electromagnetic transducer to shift the membrane back and forth in order to discharge liquid through the nozzle. Finally, the system further includes a vent to permit air to enter the ampoule as fluid is ejected from the ampoule. Preferably this vent includes a filter to prevent ingress of microbes or other contaminants to the ampoule.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: September 24, 2024
    Assignee: BAUSCH + LOMB IRELAND LIMITED
    Inventors: Reynaldo Quintana, Yehuda Ivri, Daniel V. Palanker
  • Patent number: 12048647
    Abstract: Fluid delivery devices and methods are described, where the device may comprise a piezoelectric actuator operatively coupled to an ampoule with fluid, under a preloading force. The ampoule may comprise a thin-walled thermoplastic package which includes one or more apertures positioned on the wall of the ampoule. The piezoelectric actuator may be configured to clamp at least partially around the circumference of the ampoule and apply oscillations to its wall. The oscillations, typically in ultrasonic frequency, produce cycles of acoustic pressure in the fluid, leading to ejection of the fluid droplets or streams from the apertures.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: July 30, 2024
    Assignee: Bausch + Lomb Ireland Limited
    Inventors: Yehuda Ivri, Mark S. Blumenkranz, Daniel V. Palanker
  • Patent number: 11998486
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: June 4, 2024
    Assignee: AMO Development, LLC
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Publication number: 20240058607
    Abstract: Photovoltaic retinal prosthesis is provided with optically configurable confinement of electrical field. A video stream is projected onto a retinal implant. An array of photovoltaic pixels is configured to provide retinal stimulus responsive to the video stream. The photovoltaic pixels have a common return electrode. Each pixel has an active electrode that is coupled to retinal tissue via a capacitive interface or a faradaic interface. Each pixel includes photodiode(s) connected in series between the common return electrode and the corresponding active electrode. The projected video stream is configured based on a source video stream such that one or more pixels of the retinal implant that will be dark in a next frame of the projected video stream are optically preconditioned (pre-charged) by the projected video stream during the previous frame to become sufficiently conductive to act as transient local return electrodes during the next frame of the projected video stream.
    Type: Application
    Filed: March 16, 2022
    Publication date: February 22, 2024
    Inventors: Zhijie Chen, Daniel V. Palanker, Bingyi Wang
  • Publication number: 20220304854
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Application
    Filed: June 13, 2022
    Publication date: September 29, 2022
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Patent number: 11364147
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: June 21, 2022
    Assignee: AMO Development, LLC
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Publication number: 20220176105
    Abstract: We provide a 3-dimensional configuration of an electrode array for neural cell stimulation designed to leverage migration of retinal cells into voids in the subretinal space. Walls surrounding each pixel align the electric field vertically, matching the orientation of bipolar cells in the retina, and thereby reduce the stimulation threshold. These walls also decouple the field penetration depth from the pixel width, enabling a decrease of the pixel size down to cellular dimensions. Inner retinal cells migrate into the electrode cavities, which enables very efficient stimulation. Due to 1-dimensional alignment of electric field along the cavities, stimulation threshold current density does not increase significantly with the reduced pixel size, unlike the quadratic increase seen with planar arrays.
    Type: Application
    Filed: March 25, 2020
    Publication date: June 9, 2022
    Inventors: Daniel V. Palanker, Thomas Flores
  • Publication number: 20220160542
    Abstract: Aspects of the invention include a device for fluid delivery to the ocular surface having a self-alignment system. The fluid delivery device includes a fluid package having a reservoir and one or more apertures, an actuator component configured to eject fluid from the reservoir through the one or more apertures and an image-based self-alignment system configured to align fluid ejected through the one or more apertures with a target location on the eye of a user. Also provided are methods of using the devices in fluid delivery applications, as well as a kit that includes components of the devices.
    Type: Application
    Filed: February 11, 2022
    Publication date: May 26, 2022
    Inventors: Daniel V. Palanker, Yehuda Ivri, Mark S. Blumenkranz, Reynaldo Quintana
  • Publication number: 20220054308
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Application
    Filed: November 5, 2021
    Publication date: February 24, 2022
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Publication number: 20210137732
    Abstract: A device for delivery of a precise amount of pharmaceutical fluid to the eye is provided. The device includes an ampoule for storing a liquid and an aperture through which the liquid is discharged. The device further includes a vibrating membrane that includes a needle which protrudes from the membrane and extends to the aperture to form a needle valve. The needle valve provides hermetic closure of the aperture to enable preservative-free storage of the pharmaceutical fluid in the device. The system further includes an electromagnetic transducer to shift the membrane back and forth in order to discharge liquid through the nozzle. Finally, the system further includes a vent to permit air to enter the ampoule as fluid is ejected from the ampoule. Preferably this vent includes a filter to prevent ingress of microbes or other contaminants to the ampoule.
    Type: Application
    Filed: December 18, 2020
    Publication date: May 13, 2021
    Inventors: Reynaldo Quintana, Yehuda Ivri, Daniel V. Palanker
  • Publication number: 20210128350
    Abstract: Fluid delivery devices and methods are described, where the device may comprise a piezoelectric actuator operatively coupled to an ampoule with fluid, under a preloading force. The ampoule may comprise a thin-walled thermoplastic package which includes one or more apertures positioned on the wall of the ampoule. The piezoelectric actuator may be configured to clamp at least partially around the circumference of the ampoule and apply oscillations to its wall. The oscillations, typically in ultrasonic frequency, produce cycles of acoustic pressure in the fluid, leading to ejection of the fluid droplets or streams from the apertures.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 6, 2021
    Inventors: Yehuda Ivri, Mark S. Blumenkranz, Daniel V. Palanker
  • Patent number: 10888454
    Abstract: Fluid delivery devices and methods are described, where the device may comprise a piezoelectric actuator operatively coupled to an ampoule with fluid, under a preloading force. The ampoule may comprise a thin-walled thermoplastic package which includes one or more apertures positioned on the wall of the ampoule. The piezoelectric actuator may be configured to clamp at least partially around the circumference of the ampoule and apply oscillations to its wall. The oscillations, typically in ultrasonic frequency, produce cycles of acoustic pressure in the fluid, leading to ejection of the fluid droplets or streams from the apertures.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: January 12, 2021
    Assignee: Kedalion Therapeutics, Inc.
    Inventors: Yehuda Ivri, Mark Blumenkranz, Daniel V. Palanker
  • Patent number: 10874553
    Abstract: System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: December 29, 2020
    Assignee: AMO Development, LLC
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Patent number: 10603215
    Abstract: A system and method for treating ophthalmic target tissue, including a light source for generating a beam of light, a beam delivery system that includes a scanner for generating patterns, and a controller for controlling the light source and delivery system to create a dosimetry pattern of the light beam on the ophthalmic target tissue. One or more dosage parameters of the light beam vary within the dosimetry pattern, to create varying exposures on the target tissue. A visualization device observes lesions formed on the ophthalmic target tissue by the dosimetry pattern. The controller selects dosage parameters for the treatment beam based upon the lesions resulting from the dosimetry pattern, either automatically or in response to user input, so that a desired clinical effect is achieved by selecting the character of the lesions as determined by the dosimetry pattern lesions.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: March 31, 2020
    Assignee: Topcon Medical Laser Systems, Inc.
    Inventors: Daniel V. Palanker, Dan E. Andersen
  • Publication number: 20190083305
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Application
    Filed: November 16, 2018
    Publication date: March 21, 2019
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Publication number: 20180344527
    Abstract: A system and method for treating ophthalmic target tissue, including a light source for generating a beam of light, a beam delivery system that includes a scanner for generating patterns, and a controller for controlling the light source and delivery system to create a dosimetry pattern of the light beam on the ophthalmic target tissue. One or more dosage parameters of the light beam vary within the dosimetry pattern, to create varying exposures on the target tissue. A visualization device observes lesions formed on the ophthalmic target tissue by the dosimetry pattern. The controller selects dosage parameters for the treatment beam based upon the lesions resulting from the dosimetry pattern, either automatically or in response to user input, so that a desired clinical effect is achieved by selecting the character of the lesions as determined by the dosimetry pattern lesions.
    Type: Application
    Filed: July 20, 2018
    Publication date: December 6, 2018
    Applicant: Topcon Medical Laser Systems, Inc.
    Inventors: Daniel V. PALANKER, Dan E. ANDERSEN
  • Patent number: 10130510
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: November 20, 2018
    Assignee: Optimedica Corporation
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Patent number: 10052229
    Abstract: A system and method for treating ophthalmic target tissue, including a light source for generating a beam of light, a beam delivery system that includes a scanner for generating patterns, and a controller for controlling the light source and delivery system to create a dosimetry pattern of the light beam on the ophthalmic target tissue. One or more dosage parameters of the light beam vary within the dosimetry pattern, to create varying exposures on the target tissue. A visualization device observes lesions formed on the ophthalmic target tissue by the dosimetry pattern. The controller selects dosage parameters for the treatment beam based upon the lesions resulting from the dosimetry pattern, either automatically or in response to user input, so that a desired clinical effect is achieved by selecting the character of the lesions as determined by the dosimetry pattern lesions.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: August 21, 2018
    Assignee: Topcon Medical Laser Systems, Inc.
    Inventors: Daniel V. Palanker, Dan E. Andersen
  • Patent number: 10022269
    Abstract: Patterned laser treatment of the retina is provided. A visible alignment pattern having at least two separated spots is projected onto the retina. By triggering a laser subsystem, doses of laser energy are automatically provided to at least two treatment locations coincident with the alignment spots. All of the doses of laser energy may be delivered in less than about 1 second, which is a typical eye fixation time. A scanner can be used to sequentially move an alignment beam from spot to spot on the retina and to move a treatment laser beam from location to location on the retina.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: July 17, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mark Blumenkranz, Daniel V. Palanker, Dimitri Yellachich