Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. The medical device may further include a snare device configured to transition between a contracted state within the lumen of the insertion device, and an expanded state extending distally of the insertion device. The snare device may include a loop including a pair of legs and a distal tip. The distal tip may include a plurality of stabilizers between the pair of legs.

Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. The medical device may further include a snare device configured to transition between a contracted state within the lumen of the insertion device, and an expanded state extending distally of the insertion device. The snare device may include a loop including a pair of legs and a distal tip. The distal tip may include a plurality of stabilizers between the pair of legs.

Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. The medical device may further include a snare device configured to transition between a contracted state within the lumen of the insertion device, and an expanded state extending distally of the insertion device. The snare device may include a loop including a pair of legs and a distal tip. The distal tip may include a plurality of stabilizers between the pair of legs.

Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. A snare device may be configured to transition between a retracted state within the lumen of the insertion device, and an extended state extending distally of the insertion device. The snare device may comprise a wire. A member may be disposed within the lumen of the insertion device. The member may be configured to maintain legs of the snare device in an open snare loop configuration in the extended state. In the open snare loop configuration, the wire may include an arcuate loop.

Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. A snare device may be configured to transition between a retracted state within the lumen of the insertion device, and an extended state extending distally of the insertion device. The snare device may comprise a wire. A member may be disposed within the lumen of the insertion device. The member may be configured to maintain legs of the snare device in an open snare loop configuration in the extended state. In the open snare loop configuration, the wire may include an arcuate loop.

Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. The medical device may further include a snare device configured to transition between a contracted state within the lumen of the insertion device, and an expanded state extending distally of the insertion device. The snare device may include a loop including a pair of legs and a distal tip. The distal tip may include a plurality of stabilizers between the pair of legs.

Abstract: A medical article that includes (a) an electronically conductive substrate having a specific conductivity of at least 1 ?S/cm and (b) a galvanic couple that includes a first member and a second member arranged in sufficient proximity to each other to generate a localized electric field under physiological conditions. The first and second members are selected such that the galvanic couple exhibits an average plateau current density of at least 25 microamps/cm2 when short circuited in a zero resistance ammeter test at room temperature using a saline electrolyte.

Abstract: Methods and devices provide for temporary partial aortic occlusion to achieve diversion of blood flow to the brain in patients suffering from cerebral ischemia. The device can include an expandable frame with a membrane mounted on a first portion of the frame. The membrane can have at least one opening. In some embodiments, the membrane has an outer region and an inner region, and an opening in the inner region. In use, the frame can expand to conform to the inner walls of the aorta and the membrane can at least partially occlude the aorta thereby increasing cerebral perfusion. The frame can include one or more anchors to aid in maintaining the device in position against the arterial blood flow pressure.

Abstract: An endoprosthesis includes an endoprosthesis wall that includes a ceramic coating and a polymer coating containing a therapeutic agent. A ceramic coating can be formed on the wall by electrochemical deposition. Cyclic voltammetry can be conducted to modify the density of the hydroxyl groups on the surface of the ceramic coating.

Abstract: A medical article that includes (a) an electronically conductive substrate having a specific conductivity of at least 1 ?S/cm and (b) a galvanic couple that includes a first member and a second member arranged in sufficient proximity to each other to generate a localized electric field under physiological conditions. The first and second members are selected such that the galvanic couple exhibits an average plateau current density of at least 25 microamps/cm2 when short circuited in a zero resistance ammeter test at room temperature using a saline electrolyte.

Abstract: An endoprosthesis such as a coronary stent includes a surface region that defines a depression in the form of a channel, the depression having an interior surface, and an enhanced roughness on the interior surface.

Abstract: An endoprosthesis such as a coronary stent includes a porous metal reservoir of drug, e.g. directly in the body of the stent. And a method of loading drug into the porous reservoir includes applying an electrical potential to the endoprosthesis.

Abstract: A method of cleaning and polishing an alloy comprising at least one noble metal and at least one non-noble metal, the method including the steps of submerging said alloy in an electrolytic acidic bath comprising at least one chelating or complexing agent including sulfur, and applying a multiple pulse periodic reverse waveform, and articles cleaned and/or polished thereby.

Abstract: Methods and devices provide for temporary partial aortic occlusion to achieve diversion of blood flow to the brain in patients suffering from cerebral ischemia. The device includes an expandable frame and membrane that is inserted into the aorta to partially occlude blood flow.

Abstract: A system for treating a body lumen is disclosed. The system comprises an outer stent and an inner stent disposed within the lumen of the outer stent. At least one end of the inner stent extends outside of the lumen of the outer stent, so that the end of the inner stent contacts and conforms to the body lumen wall that is adjacent the end of the outer stent. A coating can be disposed on a surface, preferably the outer surface, of the inner stent. The coating contains a therapeutic substance that may be released into the body lumen wall to help in preventing restenosis. Also disclosed is a stent having a balloon-expandable portion connected to a self-expanding portion. Methods for deploying the system and the stent are also disclosed.

Abstract: A method of cleaning and polishing an alloy comprising at least one noble metal and at least one non-noble metal, the method including the steps of submerging said alloy in an electrolytic acidic bath comprising at least one chelating or complexing agent including sulfur, and applying a multiple pulse periodic reverse waveform, and articles cleaned and/or polished thereby.

Abstract: Methods for coating metallic articles. In an exemplary embodiment, the method comprises the steps of providing a metallic article having an external surface with an oxide thereon; removing at least part of the oxide from the external surface of the article; and placing a coating on the article. The invention also includes coated metallic articles, and an apparatus for coating metallic articles.