Abstract: The present invention relates to a topical pharmaceutical composition comprising pregabalin and a reduced micellar phospholipid as an active ingredient, which results in a prolonged analgesic effect of pregabalin. The product can reduce neuropathic pain by at least 5 hours.

Abstract: The present invention relates to a topical pharmaceutical composition comprising pregabalin and a reduced micellar phospholipid as an active ingredient, which results in a prolonged analgesic effect of pregabalin. The product can reduce neuropathic pain by at least 5 hours.

Abstract: Topical formulation containing pregabalin for long-term analgesic activity. The composition is prepared using high shear mixers or homogenizers such as HPH or ultrasonic devices, which changes the structure of the composition. The analgesic effect of the compounds of the present invention is significantly increased compared to reference formulations homogenized with equipment of the same quantitative composition but less shearing forces.

Abstract: Performance of a collection of machines, arranged in a linear sequence of machines that form a linear communication orbit (LCO), is monitored. Multiple machines in the LCO receive, via the LCO, a set of rules (or various subsets of the same set of rules), each rule specifying one or a combination of conditions (e.g., a performance metric and corresponding criterion) for satisfying the rule, evaluate those rules with respect to locally occurring events and local processes, and store results of those evaluations in a local database. In response to a query sent to the machines via the LCO, each of the machines returns a report, including information identifying processes whose performance during the specified time period satisfies at least one rule in the set of one or more rules. Those reports are aggregated and used to generate a merged report reflecting performance information with respect to a set of machines.

Abstract: Example embodiments are directed to providing a zoomable meeting and collaborative canvas with image pointers. In example embodiments, a video management system establishes a zoomable meeting by communicatively coupling a plurality of user devices. A live audio/video feed is received from one or more users of the plurality of user devices. The system causes display of the zoomable meeting on a display of each of the plurality of user devices by displaying a zoomable canvas that enables movement of one or more image pointers that each show the live audio-video feed of one of the one or more users. The system monitors for an image pointer operation for one of the image pointers, whereby the image pointer operation comprises a navigation command or a zoom command. Based on the image pointer operation, the system causes an update to the zoomable canvas to display performance of the image pointer operation.

Abstract: A system is configured to enhance a video feed in real time. A live video feed captured by a video capturing device is received. A presentation of the live video feed on one or more client devices is enhanced. The enhancing includes causing a first content item of a plurality of content items to be displayed at a first location within the presentation of the five video feed. Based on a detecting of a first instance of a first gesture made by a hand at the first location in the live video feed, a content item manipulation mode with respect to the first content item is entered. The entering of the content item manipulation mode with respect to the first content includes at least one of causing the first content item to be moved within the presentation of the live video feed based on a movement of the hand or causing a scale of the first content item to be changed within the presentation of the live video feed based on a detecting of a second gesture made by the hand.

Abstract: A system is configured to enhance a video feed in real time. A live video feed captured by a video capturing device is received. A presentation of the live video feed on one or more client devices is enhanced. The enhancing includes causing a first content item of a plurality of content items to be displayed at a first location within the presentation of the live video feed. Based on a detecting of a first instance of a first gesture made by a hand at the first location in the live video feed, a content item manipulation mode with respect to the first content item is entered. The entering of the content item manipulation mode with respect to the first content includes at least one of causing the first content item to be moved within the presentation of the live video feed based on a movement of the hand or causing a scale of the first content item to be changed within the presentation of the live video feed based on a detecting of a second gesture made by the hand.

Abstract: Described herein are methods of treating cancer in a subject in need thereof comprising administering to the subject a pharmaceutical composition comprising 1-(4-(benzylamino)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide, or a pharmaceutically acceptable salt thereof, whereby the subject experiences a therapeutic response.

Abstract: Performance of a collection of machines, arranged in a linear sequence of machines that form a linear communication orbit (LCO), is monitored. Multiple machines in the LCO receive, via the LCO, a set of rules (or various subsets of the same set of rules), each rule specifying one or a combination of conditions (e.g., a performance metric and corresponding criterion) for satisfying the rule, evaluate those rules with respect to locally occurring events and local processes, and stores results of those evaluations in a local database. In response to a performance query sent to the machines via the LCO, each of the machines returns a report, including information identifying processes whose performance during the specified time period satisfies at least one rule in the set of one or more rules. Those reports are aggregated and used to present performance information to a user.

Abstract: A virtual health system is provided that creates a digital platform to connect patients to healthcare providers. Healthcare providers create profiles that describe their healthcare specialty and provide scheduling information that indicates their availability along with preferences such as appointment or meeting length, minimum break between appointment, and price. Patients create profiles that includes demographic information as well as medical records. The patients may use the system to search for available healthcare providers using a variety of criteria, and to schedule virtual health services such as video chats. The system facilitates payment for the healthcare services, and records any notes, assignments, or prescriptions generated by the healthcare provider during the services. In the event that a patient would like to engage a different healthcare provider associated with the system, the system only allows access to the patient records after receiving permission from the patient.

Abstract: A virtual health system is provided that creates a digital platform to connect patients to healthcare providers. Healthcare providers create profiles that describe their healthcare specialty and provide scheduling information that indicates their availability along with preferences such as appointment or meeting length, minimum break between appointment, and price. Patients create profiles that includes demographic information as well as medical records. The patients may use the system to search for available healthcare providers using a variety of criteria, and to schedule virtual health services such as video chats. The system facilitates payment for the healthcare services, and records any notes, assignments, or prescriptions generated by the healthcare provider during the services. In the event that a patient would like to engage a different healthcare provider associated with the system, the system only allows access to the patient records after receiving permission from the patient.

Abstract: A virtual health system is provided that creates a digital platform to connect patients to healthcare providers. Healthcare providers create profiles that describe their healthcare specialty and provide scheduling information that indicates their availability along with preferences such as appointment or meeting length, minimum break between appointment, and price. Patients create profiles that includes demographic information as well as medical records. The patients may use the system to search for available healthcare providers using a variety of criteria, and to schedule virtual health services such as video chats. The system facilitates payment for the healthcare services, and records any notes, assignments, or prescriptions generated by the healthcare provider during the services. In the event that a patient would like to engage a different healthcare provider associated with the system, the system only allows access to the patient records after receiving permission from the patient.

Abstract: A virtual health system is provided that creates a digital platform to connect patients to healthcare providers. Healthcare providers create profiles that describe their healthcare specialty and provide scheduling information that indicates their availability along with preferences such as appointment or meeting length, minimum break between appointment, and price. Patients create profiles that includes demographic information as well as medical records. The patients may use the system to search for available healthcare providers using a variety of criteria, and to schedule virtual health services such as video chats. The system facilitates payment for the healthcare services, and records any notes, assignments, or prescriptions generated by the healthcare provider during the services. In the event that a patient would like to engage a different healthcare provider associated with the system, the system only allows access to the patient records after receiving permission from the patient.

Abstract: A virtual health system is provided that creates a digital platform to connect patients to healthcare providers. Healthcare providers create profiles that describe their healthcare specialty and provide scheduling information that indicates their availability along with preferences such as appointment or meeting length, minimum break between appointment, and price. Patients create profiles that includes demographic information as well as medical records. The patients may use the system to search for available healthcare providers using a variety of criteria, and to schedule virtual health services such as video chats. The system facilitates payment for the healthcare services, and records any notes, assignments, or prescriptions generated by the healthcare provider during the services. In the event that a patient would like to engage a different healthcare provider associated with the system, the system only allows access to the patient records after receiving permission from the patient.

Abstract: A virtual health system is provided that creates a digital platform to connect patients to healthcare providers. Healthcare providers create profiles that describe their healthcare specialty and provide scheduling information that indicates their availability along with preferences such as appointment or meeting length, minimum break between appointment, and price. Patients create profiles that includes demographic information as well as medical records. The patients may use the system to search for available healthcare providers using a variety of criteria, and to schedule virtual health services such as video chats. The system facilitates payment for the healthcare services, and records any notes, assignments, or prescriptions generated by the healthcare provider during the services. In the event that a patient would like to engage a different healthcare provider associated with the system, the system only allows access to the patient records after receiving permission from the patient.

Abstract: A virtual health system is provided that creates a digital platform to connect patients to healthcare providers. Healthcare providers create profiles that describe their healthcare specialty and provide scheduling information that indicates their availability along with preferences such as appointment or meeting length, minimum break between appointment, and price. Patients create profiles that includes demographic information as well as medical records. The patients may use the system to search for available healthcare providers using a variety of criteria, and to schedule virtual health services such as video chats. The system facilitates payment for the healthcare services, and records any notes, assignments, or prescriptions generated by the healthcare provider during the services. In the event that a patient would like to engage a different healthcare provider associated with the system, the system only allows access to the patient records after receiving permission from the patient.

Abstract: Example embodiments are directed to providing a zoomable meeting and collaborative canvas with image pointers. In example embodiments, a video management system establishes a zoomable meeting by communicatively coupling a plurality of user devices. A live audio/video feed is received from one or more users of the plurality of user devices. The system causes display of the zoomable meeting on a display of each of the plurality of user devices by displaying a zoomable canvas that enables movement of one or more image pointers that each show the live audio-video feed of one of the one or more users. The system monitors for an image pointer operation for one of the image pointers, whereby the image pointer operation comprises a navigation command or a zoom command.

Abstract: A system is configured to enhance a video feed in real time. A live video feed captured by a video capturing device is received. A presentation of the live video feed on one or more client devices is enhanced. The enhancing includes causing a first content item of a plurality of content items to be displayed at a first location within the presentation of the live video feed. Based on a detecting of a first instance of a first gesture made by a hand at the first location in the live video feed, a content item manipulation mode with respect to the first content item is entered. The entering of the content item manipulation mode with respect to the first content includes at least one of causing the first content item to be moved within the presentation of the live video feed based on a movement of the hand or causing a scale of the first content item to be changed within the presentation of the live video feed based on a detecting of a second gesture made by the hand.

Abstract: The present invention relates to novel methods for the isolation and the selective ex vivo expansion of V32? TCRy6+ T cells and to their clinical application.

Abstract: The present invention relates to novel methods for the isolation and the selective ex vivo expansion of V32? TCRy6+ T cells and to their clinical application.