Abstract: The invention provides a multi-layered pharmaceutical composition comprising two or more formulations with varying properties. In some embodiments, the pharmaceutical compositions provide combinations of different organoleptic properties within the same product. In certain embodiment, these combinations allow for a modified release profile of active ingredients as the user enjoys the pharmaceutical composition. The invention further provides methods for making and using the pharmaceutical composition.

Abstract: The invention provides a multi-layered smokeless tobacco product comprising two or more formulations with varying properties. In some embodiments, the smokeless tobacco products provide combinations of different organoleptic properties within the same product. In certain embodiment, these combinations allow for a modified release profile of active ingredients as the user enjoys the smokeless tobacco product. The invention further provides methods for making and using the smokeless tobacco product.

Abstract: A method of thermally processing a tobacco material is provided, the method including the steps of (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof, to form a moist tobacco mixture; (ii) heating the moist tobacco mixture at a temperature of at least about 60° C. to form a heat-treated tobacco mixture; and (iii) incorporating the heat-treated tobacco mixture into a tobacco product.

Abstract: A method is provided for curing tobacco. The method includes steps of wilting, bruising, aerating, and drying tobacco, where each of the steps is measured in hours or days rather than months. In some aspects, aeration may take two to twelve hours or less. In some aspects, the entire curing method may be completed in 24 hours or less.

Abstract: A smokeless tobacco composition configured for insertion into the mouth of a user is provided. The smokeless tobacco composition includes a tobacco material, a sugar alcohol, and a natural gum binder component, wherein the composition is in the form of a pastille. A process for preparing a smokeless tobacco composition pastille configured for insertion into the mouth of a user is also provided. The process includes providing an aqueous mixture comprising a hydrated natural gum binder component, mixing a tobacco material with the aqueous mixture to form a smokeless tobacco mixture, heating the smokeless tobacco mixture, depositing the heated smokeless tobacco mixture into a mould, and curing the smokeless tobacco mixture to form a smokeless tobacco composition pastille.

Abstract: A smokeless tobacco composition configured for insertion into the mouth of a user is provided. The smokeless tobacco composition includes a tobacco material and a polysaccharide filler component such as polydextrose. A process for preparing a smokeless tobacco composition pastille configured for insertion into the mouth of a user is also provided. The process includes mixing a tobacco material with a binder and a polysaccharide filler component to form a smokeless tobacco mixture, injection molding the smokeless tobacco mixture, and cooling the smokeless tobacco mixture to form a solidified smokeless tobacco composition pastille. The mixing step can include forming a dry blend of the tobacco, filler, and binder components, and combining the dry blend with a viscous liquid component. The injection-molded pastille can provide a dissolvable and lightly chewable product.

Abstract: A meltable smokeless tobacco composition configured for insertion into the mouth of a user is provided. The smokeless tobacco composition includes a tobacco material and a lipid having a melting point of about 36° C. to about 45° C. An associated process is also provided. The process includes melting a lipid having a melting point of about 36° C. to about 45° C. to form a molten lipid composition, mixing a tobacco material with the molten lipid composition to form a molten smokeless tobacco composition, and cooling the molten smokeless tobacco composition to form a solidified smokeless tobacco composition.

Abstract: A method of thermally processing a tobacco material is provided, the method including the steps of (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof, to form a moist tobacco mixture; (ii) heating the moist tobacco mixture at a temperature of at least about 60° C. to form a heat-treated tobacco mixture; and (iii) incorporating the heat-treated tobacco mixture into a tobacco product.

Abstract: A meltable smokeless tobacco composition configured for insertion into the mouth of a user is provided. The smokeless tobacco composition includes a particulate tobacco material and a lipid having a melting point of about 36° C. to about 45° C. An associated process is also provided. The process includes melting a lipid having a melting point of about 36° C. to about 45° C. to form a molten lipid composition, mixing a particulate tobacco material with the molten lipid composition to form a molten smokeless tobacco composition slurry, and cooling the molten smokeless tobacco composition slurry to form a solidified smokeless tobacco composition.

Abstract: A smokeless tobacco product configured for insertion into the mouth of a user of the product is provided, the tobacco product including a water-permeable pouch containing a tobacco formulation, the tobacco formulation including a tobacco material and a plurality of microcapsules dispersed within the tobacco material, the plurality of microcapsules including an outer shell encapsulating an internal payload. The internal payload may include an additive such as water, flavorants, binders, colorants, pH adjusters, buffering agents, fillers, disintegration aids, humectants, antioxidants, oral care ingredients, preservatives, additives derived from herbal or botanical sources, and mixtures thereof. Microencapsulated flavorants include tobacco-containing flavorants, such as tobacco extracts or a particulate tobacco material, sweeteners (e.g., sweeteners containing neotame), and vanillin (optionally in a complexed form).

Abstract: A method of preparing a tobacco material for use in a smoking article is provided, including (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof; (ii) heating the mixture; and (iii) incorporating the heat-treated mixture into a smoking article as a smokable material. A smoking article in the form of a cigarette is also provided that includes a tobacco material pre-treated to inhibit reaction of asparagine to form acrylamide in mainstream smoke. Upon smoking, the smoking article is characterized by an acrylamide content of mainstream smoke that is reduced relative to an untreated control smoking article.

Abstract: A smokeless tobacco product includes a powdered or granular smokeless tobacco formulation that is contained within a moisture-permeable packet or pouch. The smokeless tobacco formulation may include finely ground particles of tobacco in powder-like form and other ingredients such as sweeteners, binders, colorants, pH adjusters, fillers, flavoring ingredients, disintegration aids, antioxidants and preservatives. The tobacco formulation may have a dry or moist form. The container has the form of a pouch or bag, such as is the type commonly used for the manufacture of snus products. The container preferably contains at least one capsule, such as a spherical breakable capsule. The container is intended to be placed in the mouth of the tobacco user, such that the tobacco formulation within the container may be enjoyed by the user. After the tobacco user is finished using the smokeless tobacco product, the container is removed from the user's mouth for disposal.

Abstract: A method of thermally processing a tobacco material is provided, the method including the steps of (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof, to form a moist tobacco mixture; (ii) heating the moist tobacco mixture at a temperature of at least about 60° C. to form a heat-treated tobacco mixture; and (iii) incorporating the heat-treated tobacco mixture into a tobacco product.

Abstract: A smokeless tobacco product configured for insertion into the mouth of a user of the product is provided, the tobacco product including a water-permeable pouch containing a tobacco formulation, the tobacco formulation including a tobacco material and a plurality of microcapsules dispersed within the tobacco material, the plurality of microcapsules including an outer shell encapsulating an internal payload. The internal payload may include an additive such as water, flavorants, binders, colorants, pH adjusters, buffering agents, fillers, disintegration aids, humectants, antioxidants, oral care ingredients, preservatives, additives derived from herbal or botanical sources, and mixtures thereof. Microencapsulated flavorants include tobacco-containing flavorants, such as tobacco extracts or a particulate tobacco material, sweeteners (e.g., sweeteners containing neotame), and vanillin (optionally in a complexed form).

Abstract: A smokeless tobacco product is provided. A water-permeable pouch containing a tobacco formulation and configured for insertion into the mouth of a user of that product is provided. The tobacco formulation includes granular tobacco and a buffer comprised of sodium carbonate and sodium bicarbonate. An outer packaging material enveloping the pouch is provided and is sealed so as to allow a controlled environment to be maintained within.

Abstract: A smoking article is provided including (a) a tobacco rod comprising a smokable filler material contained within a circumscribing outer wrapping material, wherein the smokable filler material comprises at least about 45% by weight flue-cured tobacco based on the total dry weight of the smokable filler material; (b) one or more inner wrapping strips positioned between the tobacco rod and the outer wrapping material and extending longitudinally along the tobacco rod and including a burley tobacco; and (c) a filter element connected to the tobacco rod, the filter element having an end proximal to the tobacco rod and an end distal from the tobacco rod, wherein the filter element includes at least one fibrous tow section of filter material, a general adsorbent, and an ion exchange resin.