Patents by Inventor Daniel Voytas

Daniel Voytas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TALEN-BASED GENE CORRECTION
    Publication number: 20210187006
    Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.
    Type: Application
    Filed: March 4, 2021
    Publication date: June 24, 2021
    Inventors: Mark Osborn, Jakub Tolar, Bruce Robert Blazar, Daniel Voytas
  • TALEN-based gene correction
    Patent number: 10973844
    Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: April 13, 2021
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Mark Osborn, Jakub Tolar, Bruce Robert Blazar, Daniel Voytas
  • TALEN-BASED GENE CORRECTION
    Publication number: 20190054111
    Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.
    Type: Application
    Filed: October 31, 2018
    Publication date: February 21, 2019
    Inventors: Mark Osborn, Jakub Tolar, Bruce Robert Blazar, Daniel Voytas
  • Talen-based gene correction
    Patent number: 10172880
    Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: January 8, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Mark Osborn, Jakub Tolar, Bruce Robert Blazar, Daniel Voytas
  • TALEN-BASED GENE CORRECTION
    Publication number: 20160367588
    Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.
    Type: Application
    Filed: June 15, 2016
    Publication date: December 22, 2016
    Inventors: Mark Osborn, Jakub Tolar, Bruce Robert Blazar, Daniel Voytas
  • Compositions and methods related to modified retroviral vectors for restricted, site specific integration
    Publication number: 20060154240
    Abstract: Embodiments of the invention include compositions comprising and methods utilizing a retroviral integrase complex comprising a recombinant integrase having a domain comprising a non-native protein binding site, and a DNA binding protein comprising a DNA binding domain and a peptide binding domain that binds the non-native protein binding site of the recombinant integrase.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 13, 2006
    Inventors: Paul McCray, Patrick Sinn, Daniel Voytas, Junbiao Dai
  • Retroelement vector system for amplification and delivery of nucleotide sequences in plants
    Publication number: 20050048652
    Abstract: A novel mini-retrotransposon vector system is provided for integrating foreign DNA into plants. The invention includes a novel vector comprising a truncated and modified retroelement which includes the 5? and 3? LTR regions that provide transcription initiation and termination sites as well as the cis acting sequences required for reverse transcription. Novel vectors, plant cells, and methods of using the same are disclosed.
    Type: Application
    Filed: August 18, 2004
    Publication date: March 3, 2005
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Daniel Voytas, David Wright