Patents by Inventor DANIEL W. DERWIN

DANIEL W. DERWIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoconjugates, compositions for making them, and methods of making and use
    Patent number: 9186416
    Abstract: An immunoconjugate in which a phosphate-prodrugged DNA minor groove binding agent of formula (I), where X is a nucleophilically displaceable leaving group, is conjugated to an antibody or an antigen binding fragment of an antibody, and compounds that can be used for making such immunoconjugates, and uses of such immunoconjugates.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: November 17, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Qian Zhang, Sanjeev Gangwar, Chin Pan, Daniel W. Derwin
  • IMMUNOCONJUGATES, COMPOSITIONS FOR MAKING THEM, AND METHODS OF MAKING AND USE
    Publication number: 20140364585
    Abstract: An immunoconjugate in which a phosphate-prodrugged DNA minor groove binding agent of formula (I), where X is a nucleophilically displaceable leaving group, is conjugated to an antibody or an antigen binding fragment of an antibody, and compounds that can be used for making such immunoconjugates, and uses of such immunoconjugates.
    Type: Application
    Filed: August 28, 2014
    Publication date: December 11, 2014
    Inventors: Qian ZHANG, Sanjeev Gangwar, Chin Pan, Daniel W. Derwin
  • Immunoconjugates, compositions for making them, and methods of making and use
    Patent number: 8852599
    Abstract: An immunoconjugate in which a phosphate-prodrugged DNA minor groove binding agent of formula (I), where X is a nucleophilically displaceable leaving group, is conjugated to an antibody or an antigen binding fragment of an antibody, and compounds that can be used for making such immunoconjugates, and uses of such immunoconjugates.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: October 7, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Qian Zhang, Sanjeev Gangwar, Chin Pan, Daniel W. Derwin
  • IMMUNOCONJUGATES, COMPOSITIONS FOR MAKING THEM, AND METHODS OF MAKING AND USE
    Publication number: 20120301490
    Abstract: An immunoconjugate in which a phosphate-prodrugged DNA minor groove binding agent of formula (I), where X is a nucleophilically displaceable leaving group, is conjugated to an antibody or an antigen binding fragment of an antibody, and compounds that can be used for making such immunoconjugates, and uses of such immunoconjugates.
    Type: Application
    Filed: May 22, 2012
    Publication date: November 29, 2012
    Inventors: QIAN ZHANG, SANJEEV GANGWAR, CHIN PAN, DANIEL W. DERWIN