Patents by Inventor Daniel W. ROBBINS

Daniel W. ROBBINS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIFUNCTIONAL COMPOUNDS FOR DEGRADING ITK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20250002489
    Abstract: This disclosure relates to compounds of formulae I, II and III useful for degrading ITK via a ubiquitin proteolytic pathway. This disclosure also provides pharmaceutically acceptable compositions comprising said compounds, and methods of using the compositions in the treatment of various diseases, conditions, and/or disorders.
    Type: Application
    Filed: October 19, 2022
    Publication date: January 2, 2025
    Inventors: Kerem OZBOYA, Yan MENG, Daisuke KATO, Katherine KEENAN, Ge PENG, Daniel W. ROBBINS
  • BIFUNCTIONAL COMPOUNDS FOR GRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20230024442
    Abstract: The present invention relates to compounds of formula (I) useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: November 8, 2019
    Publication date: January 26, 2023
    Inventors: Daniel W. ROBBINS, Ge PENG, Jeffrey MIHALIC, Arthur T. SANDS
  • BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20230029378
    Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: July 28, 2022
    Publication date: January 26, 2023
    Inventors: Daniel W. ROBBINS, Arthur T. SANDS, Joel MCINTOSH, Jeffrey MIHALIC, Jeffrey WU, Daisuke KATO, Dahlia WEISS, Ge PENG
  • BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20220143195
    Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: February 4, 2020
    Publication date: May 12, 2022
    Inventors: Diasuke KATO, Zef KNOST, Jeffrey MIHALIC, Daniel W. ROBBINS, Arthur T. SANDS
  • COMPOUNDS, REACTIONS, AND SCREENING METHODS
    Publication number: 20130274144
    Abstract: The invention provides a method comprising identifying a successful metal-mediated conjugation reaction by analyzing a test mixture for the presence of a conjugation product. The invention provides a two-dimensional approach to reaction discovery in which many catalysts for many catalytic reactions can be tested simultaneously to provide an efficient discovery platform. Reactants and products from the system can be identified using techniques such as gas chromatography, liquid chromatography, mass spectrometry, and combinations thereof.
    Type: Application
    Filed: August 29, 2012
    Publication date: October 17, 2013
    Applicant: The Board of Trustees of the University of Illiois
    Inventors: John F. HARTWIG, Daniel W. ROBBINS, Seth J. HERZON