Patents by Inventor Daniel W. ROBBINS

Daniel W. ROBBINS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20240124475
    Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: September 28, 2023
    Publication date: April 18, 2024
    Inventors: Daniel W. Robbins, Arthur T. SANDS, Joel MCINTOSH, Jeffrey MIHALIC, Jeffrey WU, Daisuke KATO, Dahlia WEISS, Ge PENG
  • Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway
    Patent number: 11866442
    Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: January 9, 2024
    Assignee: NURIX THERAPEUTICS, INC.
    Inventors: Daniel W. Robbins, Arthur T. Sands, Joel McIntosh, Jeffrey Mihalic, Jeffrey Wu, Daisuke Kato, Dahlia Weiss, Ge Peng
  • BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20230029378
    Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: July 28, 2022
    Publication date: January 26, 2023
    Inventors: Daniel W. ROBBINS, Arthur T. SANDS, Joel MCINTOSH, Jeffrey MIHALIC, Jeffrey WU, Daisuke KATO, Dahlia WEISS, Ge PENG
  • BIFUNCTIONAL COMPOUNDS FOR GRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20230024442
    Abstract: The present invention relates to compounds of formula (I) useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: November 8, 2019
    Publication date: January 26, 2023
    Inventors: Daniel W. ROBBINS, Ge PENG, Jeffrey MIHALIC, Arthur T. SANDS
  • Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway
    Patent number: 11479556
    Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: October 25, 2022
    Assignee: NURIX THERAPEUTICS, INC.
    Inventors: Daniel W. Robbins, Arthur T. Sands, Joel McIntosh, Jeffrey Mihalic, Jeffrey Wu, Daisuke Kato, Dahlia Weiss, Ge Peng
  • BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
    Publication number: 20220143195
    Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: February 4, 2020
    Publication date: May 12, 2022
    Inventors: Diasuke KATO, Zef KNOST, Jeffrey MIHALIC, Daniel W. ROBBINS, Arthur T. SANDS
  • COMPOUNDS, REACTIONS, AND SCREENING METHODS
    Publication number: 20130274144
    Abstract: The invention provides a method comprising identifying a successful metal-mediated conjugation reaction by analyzing a test mixture for the presence of a conjugation product. The invention provides a two-dimensional approach to reaction discovery in which many catalysts for many catalytic reactions can be tested simultaneously to provide an efficient discovery platform. Reactants and products from the system can be identified using techniques such as gas chromatography, liquid chromatography, mass spectrometry, and combinations thereof.
    Type: Application
    Filed: August 29, 2012
    Publication date: October 17, 2013
    Applicant: The Board of Trustees of the University of Illiois
    Inventors: John F. HARTWIG, Daniel W. ROBBINS, Seth J. HERZON