Abstract: Viewing and manipulation systems and methods for medical images shown on a display. The method includes the steps of observing a multiple-person medical environment using a camera having a field of view, and sending field-of-view data of the multiple-person medical environment from the camera to a processor. The processor performs the steps of (i) analyzing the field-of-view data to identify a target practitioner and define a target practitioner-based, non-uniform coordinate frame connected to the target practitioner; (ii) monitoring a time-series of the field-of-view data to identify at least one input communicated by a gesture performed by the target practitioner in the target practitioner-based, non-uniform coordinate frame; and (iii) manipulating a medical image shown by the display in response to identifying the at least one input.