Patents by Inventor Daniel Wahl

Daniel Wahl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF ASSESSING METABOLIC FLUX
    Publication number: 20260063623
    Abstract: The present disclosure relates to methods for assessing metabolic flux. In some aspects, the disclosure relates to methods for estimating absolute metabolic flux for a pathway of interest based upon a level of one or more metabolites and/or isotopologues thereof at a single point in time following administration of a tracer to a subject. In some embodiments, the methods described herein are performed or generated using artificial intelligence/machine-learning (AI/ML) models.
    Type: Application
    Filed: October 13, 2023
    Publication date: March 5, 2026
    Inventors: Andrew Scott, Abhinav Achreja, Anjali Mittal, Deepak Nagrath, Costas A. Lyssiotis, Daniel Wahl, Baharan Meghdadi
  • Compositions for the treatment of brain tumors
    Patent number: 12357615
    Abstract: The instant invention describes pharmaceutical compositions and dosing regimens comprising radiation therapy and seviteronel with or without dexamethasone, and methods of treating diseases, disorders or symptoms thereof.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: July 15, 2025
    Assignees: Kembi Therapeutics Pty Ltd, The Regents of the University of Michigan, The United States Government as represented by The Department of Veterans Affairs
    Inventors: Joel Eisner, Daniel Wahl, Corey Speers
  • COMPOSITIONS FOR THE TREATMENT OF BRAIN TUMORS
    Publication number: 20220370415
    Abstract: The instant invention describes pharmaceutical compositions and dosing regimens comprising radiation therapy and seviteronel with or without dexamethasone, and methods of treating diseases, disorders or symptoms thereof.
    Type: Application
    Filed: October 11, 2019
    Publication date: November 24, 2022
    Applicants: Kembi Therapeutics Pty Ltd, The Regents of the University of Michigan, The United States Government as represented by The Department of Veterans Affairs
    Inventors: Joel Eisner, Daniel Wahl, Corey Speers
  • METHODS OF DETERMINING TREATMENT CONSISTING OF RADIATION THERAPY AND/OR ALKYLATING CHEMOTHERAPY IN PATIENTS SUFFERING FROM CANCER
    Publication number: 20210317535
    Abstract: Methods of treating a tumor in a subject are provided herein. In exemplary embodiments, the method comprises measuring the expression level of MGMT, GPRASP1, CHGA, MAPK8, ATP6V0A2, or FGF7, or any combination thereof, in a sample comprising a cell or cells from the tumor, and administering to the subject an alkylating chemotherapy, radiation therapy, or a combination comprising alkylating chemotherapy and radiation therapy, depending on the expression level(s). Related methods, kits, systems, computer-readable storage media, and methods implemented by a processor in a computer are further provided herein.
    Type: Application
    Filed: August 29, 2019
    Publication date: October 14, 2021
    Inventors: Daniel Wahl, Shuang Zhao, Jann Sarkaria
  • PREDICTIVE RENAL SAFETY BIOMARKERS AND BIOMARKER SIGNATURES TO MONITOR KIDNEY FUNCTION
    Publication number: 20140171335
    Abstract: Biomarker signatures were identified which can be used to diagnose or predict kidney or liver toxicity and more specifically renal tubular toxicity as a consequence of disease or drug treatment.
    Type: Application
    Filed: November 27, 2013
    Publication date: June 19, 2014
    Applicant: NOVARTIS AG
    Inventors: Gerard MAURER, Frank DIETERLE, Elias PERENTES, Frank STAEDTLER, Andre CORDIER, Andreas MAHL, Jacky VONDERSCHER, Daniel WAHL, Olivier GRENET, Daniel Robert ROTH
  • Use of ?-2-microglobulin to assess glomerular alterations and damage in the kidney
    Patent number: 8609812
    Abstract: The present invention is directed, in part, to a method of measuring ?-2-microglobulin to assess glomerular alteration or damage of the kidney.
    Type: Grant
    Filed: March 25, 2008
    Date of Patent: December 17, 2013
    Assignee: Novartis AG
    Inventors: Gerard Maurer, Frank Dieterle, Elias Perentes, Frank Städtler, André Cordier, Andreas Mahl, Jacky Vonderscher, Daniel Wahl, Olivier Grenet, Daniel Robert Roth
  • PREDICTIVE RENAL SAFETY BIOMARKERS AND BIOMARKER SIGNATURES TO MONITOR KIDNEY FUNCTION
    Publication number: 20100143956
    Abstract: Biomarker signatures were identified which can be used to diagnose or predict kidney or liver toxicity and more specifically renal tubular toxicity as a consequence of disease or drug treatment.
    Type: Application
    Filed: March 25, 2008
    Publication date: June 10, 2010
    Inventors: Gerard Maurer, Frank Dieterle, Elias Perentes, Frank Stadtler, Andre Cordier, Andreas Mahl, Jacky Vonderscher, Daniel Wahl, Olivier Grenet, Daniel R. Roth