Abstract: A multimedia player downloads chunks (parts of the segment file) during the download of a segment of a stream of segments of a low-latency stream. The first chunks of a segment may be downloaded while the segment is still being written to the CDN server. A chunk-based prediction adaptation logic uses throughput measurements on a chunk instead of a segment and specifically looks at bursts in a sliding window. This data is used to build a prediction of future throughput by applying linear adaptive filter algorithms that may rely on recursive least squares. This adaptation logic leads to very accurate bandwidth predictions and as a consequence, better user experience, compared to existing adaptation algorithms.

Abstract: A multimedia player downloads chunks (parts of the segment file) during the download of a segment of a stream of segments of a low-latency stream. The first chunks of a segment may be downloaded while the segment is still being written to the CDN server. A chunk-based prediction adaptation logic uses throughput measurements on a chunk instead of a segment and specifically looks at bursts in a sliding window. This data is used to build a prediction of future throughput by applying linear adaptive filter algorithms that may rely on recursive least squares. This adaptation logic leads to very accurate bandwidth predictions and as a consequence, better user experience, compared to existing adaptation algorithms.

Abstract: A client configured to retrieve a live-stream media content is shown. The client is configured to receive from a live-streaming server a media presentation description (MPD) describing live-stream media content composed of a sequence of segments and an information on a current segment of the sequence of segments. The client is further configured to commence retrieving the live-stream media content from the live-streaming server from a predetermined segment of the sequence of segments onwards, which the client determined based on the information.

Abstract: A client configured to retrieve a live-stream media content is shown. The client is configured to receive from a live-streaming server a media presentation description (MPD) describing live-stream media content composed of a sequence of segments and an information on a current segment of the sequence of segments. The client is further configured to commence retrieving the live-stream media content from the live-streaming server from a predetermined segment of the sequence of segments onwards, which the client determined based on the information.

Abstract: A video streaming system optimizes the buffering of periods of frames of a video presentation in order to achieve a more constant perceptual quality throughout the entire video presentation. An adaption algorithm determines transmission bitrates to transmit some periods at a lower bitrate that the channel conditions of the channel may allow while transmitting other periods at a higher bitrate. The transmission bitrates are determined based on expected quality metadata signaled in the periods of the bitstream for the current period and following periods in order to optimize the bitrate and the expected perceptual quality of each version of each period over time.

Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.

Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.

Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.

Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.

Abstract: A client configured to retrieve a live-stream media content is shown. The client is configured to receive from a live-streaming server a media presentation description (MPD) describing live-stream media content composed of a sequence of segments and an information on a current segment of the sequence of segments. The client is further configured to commence retrieving the live-stream media content from the live-streaming server from a predetermined segment of the sequence of segments onwards, which the client determined based on the information.

Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.

Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.

Abstract: The invention provides a method of detecting impaired prefrontal cognitive function in an individual by determining the individual's COMT genotype, and associating a high activity Val allele with impaired prefrontal cognitive function (and a low activity Met allele with enhanced prefrontal cognitive function).

Abstract: The invention is related to the discovery that a met66val polymorphism in the gene for brain-derived neurotrophic factor (BDNF) is correlated with hippocampal function and verbal memory and risk for neuropsychiatric disorders such as schizophrenia.