Patents by Inventor Daniel Wettstein

Daniel Wettstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBK1 AND/OR IKK EPSILON
    Publication number: 20150352108
    Abstract: The invention relates to certain amino-pyrimidine compounds which inhibit TBK1 and/or IKK epsilon and which may therefore find application in treating inflammation, cancer, septic shock and/or Primary open Angle Glaucoma (POAG).
    Type: Application
    Filed: December 23, 2014
    Publication date: December 10, 2015
    Applicant: Alzheimer's Institute of America
    Inventors: Ryan C. Holcomb, Kazuyuki Suzuki, Robert J. Halter, Paul R. Sebahar, Donald A. McLeod, Mark D. Shenderovich, Kraig M. Yager, Matthew Gregory Bursavich, Ashantai J. Yungai, Burt Richards, Paul L. Bartel, Daniel A. Wettstein
  • Purine-core inhibitors of HSP90 and their use in treating cancer
    Patent number: 8476285
    Abstract: The invention relates to compounds of Formulae I-III: and therapeutic uses thereof, wherein A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carbocyclic group; B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group; R1 is chosen from hydro, alkyl, aryl, heteroaryl, amino, or halo; and L1, L2, are as defined herein.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: July 2, 2013
    Assignee: Myrexis, Inc.
    Inventors: Ashok C. Bajji, Se-Ho Kim, Benjamin Markovitz, Richard Trovato, Rajendra Tangallapally, Mark B. Anderson, Daniel Wettstein, Mark Shenderovich, John A. Vanecko
  • Methods of Treating Diseases, Pharmaceutical Compositions, and Pharmaceutical Dosage Forms
    Publication number: 20120277257
    Abstract: Disclosed herein are methods of treating diseases and disorders responsive to inhibition of Hsp90, pharmaceutical compositions, pharmaceutical dosage forms and medicaments useful for the treatment of diseases responsive to inhibition of Hsp90, and methods of making the pharmaceutical compositions, pharmaceutical dosage forms and medicaments.
    Type: Application
    Filed: May 14, 2012
    Publication date: November 1, 2012
    Applicant: MYREXIS, INC.
    Inventors: Margaret YU, Daniel A. WETTSTEIN, Vijay R. BAICHWAL, Damon I. PAPAC, Gaylen M. ZENTNER, Mark S. WILLIAMS
  • AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF IKK EPSILON AND/OR TBK1
    Publication number: 20120238540
    Abstract: The invention relates to certain amino-pyrimidine compounds that inhibit IKK epsilon and/or TBK1, methods of making such compounds, pharmaceutical compositions comprising such compounds, and the use of these compounds in treating a variety of diseases and disorders.
    Type: Application
    Filed: April 12, 2012
    Publication date: September 20, 2012
    Applicant: Myrexis, Inc.
    Inventors: Ryan C. HOLCOMB, Kazuyuki Suzuki, Robert J. Halter, Paul R. Sebahar, Donald A. McLeod, Mark D. Shenderovich, Kraig M. Yager, Matthew Gregory Bursavich, Ashantai J. Yungai, Burt Richards, Paul L. Bartel, Daniel A. Wettstein
  • Therapeutic Compounds and Their Use in Treating Diseases and Disorders
    Publication number: 20100292255
    Abstract: The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders, such as cancer.
    Type: Application
    Filed: May 14, 2010
    Publication date: November 18, 2010
    Applicant: Myriad Pharmaceuticals, Inc.
    Inventors: Ashok C. Bajji, Se-Ho Kim, Rajendra Tangallapally, Benjamin J. Markovitz, Richard Trovato, Mark B. Anderson, Daniel A. Wettstein, Mark D. Shenderovich
  • THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER
    Publication number: 20100016586
    Abstract: The invention relates to compounds of Formulae I-III and their therapeutic uses.
    Type: Application
    Filed: June 30, 2009
    Publication date: January 21, 2010
    Applicant: Myriad Genetics, Incorporated
    Inventors: ASHOK C. BAJJI, Se-Ho Kim, Benjamin Markovitz, Richard Trovato, Rajendra Tangallapally, Mark B. Anderson, Daniel Wettstein, Mark Shenderovich, John A. Vanecko
  • Therapeutic compounds and their use in cancer
    Patent number: 7595401
    Abstract: The invention relates to compounds of Formula I and their therapeutic uses, wherein substituent A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carboxylic group, B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group, R1 is chosen from hydro, alkyl, aryl, heteroaryl amino and halo, and L1 and L2 are as defined in the specification.
    Type: Grant
    Filed: May 14, 2007
    Date of Patent: September 29, 2009
    Assignee: Myriad Pharmaceuticals, Inc.
    Inventors: Ashok C. Bajji, Se-Ho Kim, Benjamin Markovitz, Richard Trovato, Rajendra Tangallapally, Mark B. Anderson, Daniel Wettstein, Mark Shenderovich, John A. Vanecko
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES
    Publication number: 20090082265
    Abstract: Protein complexes are provided comprising at least one interacting pair of proteins. The protein complexes are useful in screening assays for identifying compounds effective in modulating the protein complexes, and in treating and/or preventing diseases and disorders associated with the protein complexes and/or their constituent interacting members.
    Type: Application
    Filed: October 1, 2007
    Publication date: March 26, 2009
    Applicant: Myriad Genetics, Incorporated
    Inventors: Paul Bartel, Daniel Cimbora, Janice Sugiyama, Daniel A. Wettstein, Karen Heichman
  • THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER
    Publication number: 20070299258
    Abstract: The invention relates to compounds of Formulae I-III and their therapeutic uses.
    Type: Application
    Filed: May 14, 2007
    Publication date: December 27, 2007
    Applicant: Myriad Genetics, Incorporated
    Inventors: Ashok Bajji, Se-Ho Kim, Benjamin Markovitz, Richard Trovato, Rajendra Tangallapally, Mark Anderson, Daniel Wettstein, Mark Shenderovich, John Vanecko
  • COMPOSITION AND METHOD FOR TREATING HIV INFECTION
    Publication number: 20070213271
    Abstract: Methods for inhibiting HIV propagation and treating HIV infection are provided which include administering to cells infected with HIV a compound capable of inhibiting viral budding from the infected host cells. The methods are especially useful in treating HIV infection and in treating and preventing AIDS.
    Type: Application
    Filed: January 24, 2007
    Publication date: September 13, 2007
    Applicant: Myriad Genetics, Incorporated
    Inventors: Kenton Zavitz, Daniel Wettstein, Scott Morham, Adrian Hobden
  • Compositions and methods for treating diseases
    Publication number: 20050222029
    Abstract: Protein complexes are provided comprising at least one interacting pair of proteins. The protein complexes are useful in screening assays for identifying compounds effective in modulating the protein complexes, and in treating and/or preventing diseases and disorders associated with the protein complexes and/or their constituent interacting members.
    Type: Application
    Filed: March 7, 2005
    Publication date: October 6, 2005
    Applicant: Myriad Genetics, Incorporated
    Inventors: Paul Bartel, Daniel Cimbora, Janice Sugiyama, Daniel Wettstein, Karen Heichman