Abstract: Certain trifarotene fatty acid esters and external, topical skin care compositions containing one or more such compounds are described. In some embodiments, upon hydrolysis in the skin, shorter chain trifarotene fatty acid esters release short chain fatty acids such as octanoic acid and lauric acid, which are known to contribute to penetration enhancement in topical skin delivery. Methods of topically applying the external compositions to the skin of a subject to inhibit or reduce signs of photoaging or acne are also described.

Abstract: Various salts of tranexamic acid esters compounds are described, along with compositions including such compounds. Methods of use for treatment of external surfaces (e.g. skin) and processes of producing the compounds and compositions are also described.

Abstract: A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

Abstract: External compositions containing one or more lipophilic naphthoic acid retinoid compounds are described. The external compositions are applied to skin where they stimulate skin repair and visibly improve skin damage caused by photoaging and acne.

Abstract: Disclosed are cyclopentene compounds and compositions containing one or more odorless lipophilic compounds cyclopentene compounds. The compositions can be applied to scalp where they stimulate hair follicles resulting in hair growth and visibly improved human hair.

Abstract: Various compositions and methods for treating or preventing damage to hair, especially in over-processed or chemically treated hair, are described. The various compositions comprise itaconic acid, or a salt, ester, or anhydride thereof, and are applied in the absence of any oxidizing agent.

Abstract: Disclosed are cyclopentene compounds and compositions containing one or more odorless lipophilic compounds cyclopentene compounds. The compositions can be applied to scalp where they stimulate hair follicles resulting in hair growth and visibly improved human hair.

Abstract: Various salts of tranexamic acid esters compounds are described, along with compositions including such compounds. Methods of use for treatment of external surfaces (e.g. skin) and processes of producing the compounds and compositions are also described.

Abstract: A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

Abstract: External compositions containing one or more lipophilic naphthoic acid retinoid compounds are described. The external compositions are applied to skin where they stimulate skin repair and visibly improve skin damage caused by photoaging and acne.

Abstract: A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

Abstract: Various compositions and methods for treating or preventing damage to hair, especially in over-processed or chemically treated hair, are described.

Abstract: Various compositions and methods for treating or preventing damage to hair, especially in over-processed or chemically treated hair, are described.

Abstract: A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

Abstract: A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

Abstract: The invention includes a diester exhibiting improved hydrolytic stability that is an esterification product of a 1-methylheptyl alcohol and a dicarboxylic acid. In some embodiments, the diester is bis(1-methyl heptyl) butanedioate, bis(1-methyl heptyl) nonanedioate and/or bis(1-methyl heptyl) decanedioate. The diester may be natural and/or not sourced from palm. Also contemplated within the scope of the invention are diesters exhibiting improved hydrolytic stability represented by Formula (I): wherein R1 is chosen from a linear alkyl group containing four to ten carbon atoms.

Abstract: A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

Abstract: The invention includes a diester exhibiting improved hydrolytic stability that is an esterification product of a 1-methylheptyl alcohol and a dicarboxylic acid. In some embodiments, the diester is bis(1-methyl heptyl) butanedioate, bis(1-methyl heptyl) nonanedioate and/or bis(1-methyl heptyl) decanedioate. The diester may be natural and/or not sourced from palm. Also contemplated within the scope of the invention are diesters exhibiting improved hydrolytic stability represented by Formula (I): wherein R1 is chosen from a linear alkyl group containing four to ten carbon atoms.

Abstract: Described herein is a silicone replacement for use in a personal care formulation comprising a mixture of at least one polymeric ester and at least one non-polymeric ester. The polymeric ester is an esterification reaction product of (i) at least one first dicarboxylic acid, (ii) at least one first monofunctional alcohol or monofunctional carboxylic acid and (iii) glycerin or derivatives thereof. The non-polymeric ester is an esterification reaction product of (i) at least one second dicarboxylic acid and (ii) at least one second monofunctional alcohol, wherein the replacement is substantially free of silicone. As described is a personal care formulation that is substantially free of silicone, wherein the formulation comprises a silicone replacement consisting substantially of a mixture of at least one polymeric ester as described above, and a non-polymeric ester as described above. Related methods are also described.

Abstract: The invention includes an UV absorbing complex polyol polyester polymer that is the product of a reaction scheme that includes: (i) the esterification of a polyol and a dianhydride, wherein the esterification is carried out under conditions that facilitate substantially only anhydride opening, to form a polyester polymer comprising at least two pendant carboxylic groups, and at least two hydroxyl groups: and (ii) the reaction of at least one pendant carboxylic group and at least one terminal hydroxyl group of the polyester polymer with an epoxide having a functional group, wherein the epoxide comprises an UV absorbing moiety. Also included are linear UV absorbing complex polyol polyester polymers represented by Formula (XI): wherein R3 is independently selected from an UV absorbing moiety; R4 and R5 are each independently selected from a hydrocarbon group, and n is an integer of 1 to 1000.