Abstract: An intracranial pressure measurement device has a first plate abutting a patient's dura mater and displaced from a second plate abutting an endocranial surface of the patient's skull. The displacement of the first plate and second plate during elevated intracranial pressures are indicated visually on the device and visible through, e.g., X-ray imaging. This allows the intracranial pressure to be correlated to the mechanical displacement of the first plate from the second plate.

Abstract: A method performed a local device that is communicatively coupled with several remote devices, the method includes: receiving, from each remote device with which the local device is engaged in a communication session, an input audio stream; receiving, for each remote device, a set parameters; determining, for each input audio stream, whether the input audio stream is to be 1) rendered individually or 2) rendered as a mix of input audio streams based on the set of parameters; for each input audio stream that is determined to be rendered individually, spatially rendering the input audio stream as an individual virtual sound source that contains only that input audio stream; and for input audio streams that are determined to be rendered as the mix of input audio streams, spatially rendering the mix of input audio streams as a single virtual sound source that contains the mix of input audio streams.

Abstract: Methods and apparatus to select and present level-change way points for indoor navigation systems are disclosed. An example method includes: receiving, from a client device having a navigation system interface, a request for navigation directions from a starting point to a destination point; identifying, by one or more processors, a plurality of level-change way points based on a starting level associated with the starting point; determining, by one or more processors, a subset of two or more of the plurality of level-change way points based on a destination level associated with the destination point; selecting, by one or more processors, a selected level-change way point from the subset based upon one or more criteria; and providing, to the client device, directions to present an indication of a location of the selected level-change way point in the navigation system user interface.

Abstract: An autonomous vehicle for performing gardening tasks, the vehicle including a motorized wheeled chassis with at least one motor providing power to a plurality of wheels, at least one rotating wheel attached to the motorized wheeled chassis, a line or blade extending from the rotating wheel configured to perform a selected gardening task, at least one of a downward-facing camera or an outward-facing camera, and a processor configured to control processing related to determining a position of the motorized wheeled chassis, driving the at least one motor to move one or more of the plurality of wheels, rotating the at least one rotating wheel when the selected gardening task is performed, and correcting a path of the motorized wheeled chassis based on one or more images obtained from the at least one of the downward-facing camera or the outward-facing camera.

Abstract: The present approach relates to techniques for facilitating acquisition of electronic signatures (e-signatures) and/or acknowledgements in the context of electronic forms or documents. In one aspect, a designer may be used to configure tasks corresponding to signature or acknowledgment events that may be added to a person's to-do list or task management application or portal. Interaction with the task to complete the task may then be in accordance with the guidance programmed by the designer, such as to acquire a signature or acknowledgment. In certain aspects, the signature or acknowledgement tasks may be configured for display and completion on a mobile device (e.g., a handheld device such as a phone or tablet computer).

Abstract: In an integrated circuit that provides a clock signal, an asymmetric frequency-locked loop (AFLL) includes a first digitally controlled oscillator (DCO) that outputs a first signal having a first fundamental frequency, and a second DCO that outputs a second signal having a second fundamental frequency that is less than the first fundamental frequency. Moreover, the AFLL includes control logic that selects one of the first DCO and the second DCO based on an instantaneous value of a power-supply voltage and an average power-supply voltage so that an impact of power-supply voltage variations on a time-critical path in the integrated circuit is reduced. For example, the control logic may select the first DCO if the instantaneous value of the power-supply voltage is greater than the average power-supply voltage; otherwise, the control logic may select the second DCO.

Abstract: Methods for enhancing the lysis of coagulated blood comprise administering to coagulated blood a combination of clot clysis agent and a lysis enhancing amount of apolipoprotein E2 (Apo E2) or a therapeutic derivative thereof. Methods for reducing the risk of blood coagulation comprise administering to blood a combination of a clot lysis agent and a lysis enhancing amount of Apo E2 or a therapeutic derivative thereof. Additional methods for enhancing the lysis of coagulated blood comprise administering to an individual a specific level of clot lysis agent wherein the specific level is based upon the apolipoprotein phenotype of the individual. Further methods for reducing the risks of blood coagulation comprise administering to blood a specific level of a clot lysis agent wherein the specific level is based upon the apolipoprotein phenotype of the individual.

Abstract: Methods for inhibiting lysis of coagulated blood and reducing risk of excessive lysis comprising administration of lysis-inhibiting amounts of apolipoprotein E4, and methods for inhibiting lysis of coagulated blood and reducing risk of excessive lysis comprising administration of a specific level of a lysis-inhibiting agent wherein the specific level is based on the apolipoprotein phenotype of an individual, are provided. Methods for enhancing lysis of coagulated blood by administration of an Apo E peptide fragment to blood containing a clot lysis agent are also provided.

Abstract: A highly sensitive accelerometer for determining the acceleration of a structure includes a mass within a housing suspended by opposing support members. The support members are alternately wound around a pair of fixed mandrels and the mass in a push pull arrangement. At least a portion of one of the support members comprises a transducer capable measuring the displacement of the mass within the housing. An embodiment of the invention employs optical fiber coils as the support members for use in interferometric sensing processes. Arrays of such interferometer based accelerometers may be multiplexed using known techniques.

Abstract: A method and apparatus for reducing the difficulty of controlling the length of a section of optical waveguide wrapped around a mandrel separating Bragg gratings forming an interferometric sensor are provided. The section of optical waveguide may be wrapped on a mandrel having at least two different outer diameters. The mandrel may also include one or more bores for receiving and protecting the Bragg gratings.

Abstract: A pressure compensated hydrophone for measuring dynamic pressures is disclosed. The hydrophone includes a compliant hollow mandrel with a single optical fiber coiled around at least a portion of the mandrel. The mandrel further includes at least one pressure relief valve for compensating for changes in hydrostatic pressure. The pressure relief valve includes a micro-hole, which allows hydrostatic pressures or low frequency pressure events to couple into the interior of the mandrel to provide compensation against such pressure. Higher frequencies pressure events of interest do not couple through the micro-hole and therefore only act only on the exterior of the mandrel, allowing for their detection. Because (quasi) hydrostatic events are compensated for, the mandrel may be made particularly compliant, rendering the singular fiber optic coil particularly sensitive to the detection of the higher frequency signals of interest.

Abstract: A highly sensitive accelerometer for determining the acceleration of a structure includes a mass within a housing suspended by opposing support members. The support members are alternately wound around a pair of fixed mandrels and the mass in a push pull arrangement. At least a portion of one of the support members comprises a transducer capable measuring the displacement of the mass within the housing. An embodiment of the invention employs optical fiber coils as the support members for use in interferometric sensing processes. Arrays of such interferometer based accelerometers may be multiplexed using known techniques.

Abstract: A method for coining holographic images or holograms in a contoured or tapered surface of hard metal articles such as automotive products and sporting and fitness products including ball bats using a split die having an interior surface mirroring the contoured or tapered surface of the metal article.

Abstract: A highly sensitive accelerometer for determining the acceleration of a structure includes a mass within a housing suspended by opposing support members. The support members are alternately wound around a pair of fixed mandrels and the mass in a push pull arrangement. At least a portion of one of the support members comprises a transducer capable measuring the displacement of the mass within the housing. An embodiment of the invention employs optical fiber coils as the support members for use in interferometric sensing processes. Arrays of such interferometer based accelerometers may be multiplexed using known techniques.

Abstract: Methods for inhibiting the lysis of coagulated blood comprise administering to blood a lysis-inhibiting amount of apolipoprotein E4 (Apo E4) or a therapeutic derivative thereof. Methods for reducing the risk of excessive blood clot lysis comprise administering the blood a lysis-inhibiting amount of Apo E4 or a therapeutic derivative thereof. Additional methods for inhibiting the lysis of coagulated blood comprise administering to an individual's blood a specific level of a lysis-inhibiting amount of Apo E4 wherein the specific level is based upon the apolipoprotein phenotype of the individual. Further methods for reducing the risk of excessive blood clot lysis comprise administering to an individual's blood a specific level of a lysis-inhibiting amount of Apo E4, wherein the specific level is based upon the apolipoprotein phenotype of the individual. Additional methods for enhancing the lysis of coagulated blood comprise administering to blood containing a clot lysis agent an Apo E peptide fragment.

Abstract: Methods for enhancing teh lysis of coagulated blood comprise administering to coagulated blood a combination of clot clysis agent and a lysis enhancing amount of apolipoprotein E2 (Apo E2) or a therapeutic derivative thereof. Methods for reducing the risk of blood coagulation comprise administering to blood a combination of a clot lysis agent and a lysis enhancing amount of Apo E2 or a therapeutic derivative thereof. Additional methods for enhancing the lysis of coagulated blood comprise administering to an individual a specific level of clot lysis agent wherein the specific level is based upon the apolipoprotein phenotype of the individual. Further methods for reducing the riks of blood coagulation comprise administering to blood a specific level of a clot lysis agent wherein the specific level is based upon the apolipoprotein phenotype of the individual.

Abstract: A highly sensitive accelerometer for determining the acceleration of a structure includes a mass within a housing suspended by opposing support members. The support members are alternately wound around a pair of fixed mandrels and the mass in a push pull arrangement. At least a portion of one of the support members comprises a transducer capable measuring the displacement of the mass within the housing. An embodiment of the invention employs optical fiber coils as support members for use in interferometric sensing processes. Arrays of such interferometer based accelerometers maybe multiplexed using WDM or similar methods.

Abstract: A highly sensitive accelerometer for determining the acceleration of a structure includes a mass within a housing suspended by opposing support members. The support members are alternately wound around a pair of fixed mandrels and the mass in a push pull arrangement. At least a portion of one of the support members comprises a transducer capable measuring the displacement of the mass within the housing. An embodiment of the invention employs optical fiber coils as the support members for use in interferometric sensing processes. Arrays of such interferometer based accelerometers may be multiplexed using known techniques.