Abstract: A device for maintaining an optical path of an optical imaging system free of fog includes an elongated member having a distal end and a proximal end, a near-infrared (NIR) light-absorbing optical window disposed at the distal end, and an optical system disposed along the optical path. The device also includes a coupling module coupled to the elongated member at the proximal end and configured to transmit near-infrared light to the NIR light-absorbing optical window along the optical path and receive a light beam from an area of interest along the optical path.

Abstract: A locking structure of a Bowens mount, configured to lock a luminaire with an optical accessory having a Bowens mount, including a rotating member and a mount provided on a luminaire front housing, in which the mount is provided on a peripheral side of a light outlet aperture of the luminaire front housing, the rotating member is threaded to the mount, the mount includes three grooves fitted with protrusions of the Bowens mount, a height of each groove is lower than that of each protrusion of the Bowens mount, and the rotating member includes notch parts corresponding to at least three grooves.

Abstract: The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.

Abstract: Silicone roofing materials are provided. A roofing material comprises at least one of a plurality of particles, a silicone coating, a substrate, an adhesive layer, a release liner, or any combination thereof. The substrate is located between the silicone coating and the adhesive layer. The adhesive layer is located between the substrate and the release liner. The release liner covers at least a portion of the adhesive layer. The plurality of particles covers at least a portion of a surface of the silicone coating. Each of the plurality of particles has a surface. When the roofing material is installed on a roofing substrate, at least a portion of the surface of the plurality of particles is exposed to an environment. Related systems and related methods are also provided.

Abstract: The invention provides methods of making immune effector cells (e.g., T cells, NK cells) that can be engineered to express a chimeric antigen receptor (CAR), compositions and reaction mixtures comprising the same, and methods of treatment using the same.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: Embodiments provide image display systems and methods for a camera calibration using a two-sided diffractive optical element (DOE). More specifically, embodiments are directed to determining intrinsic parameters of a camera using a single image obtained using a two-sided DOE. The two-sided DOE has a first pattern on a first surface and a second pattern on a second surface. Each of the first and second patterns may be formed by repeating sub-patterns that are lined when tiled on each surface. The patterns on the two-sided DOE are formed such that the brightness of the central intensity peak on the image of the image pattern formed by the DOE is reduced to a predetermined amount.

Abstract: The present disclosure provides compositions which enable the delivery of cargo, including therapeutic agents such as RNA, to organs or tissues in addition to the liver, lungs, and spleen, such as brain, heart, kidney, and muscle tissue. More specifically, the compositions comprise a plurality of lipid particles comprising an agent, cationic lipids and ionizable lipid.

Abstract: An example method includes providing, to a sequence model (i) a plurality of few-shot prompts, wherein each prompt comprises a demonstration passage, a demonstration task, and a demonstration query, wherein the demonstration task describes a type of retrieval, and wherein the demonstration query is relevant to the demonstration task, and (ii) a plurality of passages sampled from a corpus of passages. The method also includes receiving, from the sequence model and for the plurality of passages and based on the plurality of few-shot prompts, a respective plurality of predicted task-query pairs, the sequence model having been prompted to predict a task based on an input passage, and predict an output query relevant to the predicted task. The method further includes generating a synthetic training dataset comprising the plurality of passages and the respective plurality of predicted task-query pairs. The method also includes providing the synthetic training dataset.

Abstract: Exemplary embodiments may include a method of applying a charging pulse to an output capacitor, detecting satisfaction of a charging threshold, ending the charging pulse in response to the detecting the satisfaction of the charging threshold, and discharging the sampling capacitor in response to the detecting the satisfaction of the charging threshold. In some embodiments, once a sampling capacitor voltage drops below a discharging threshold, a charging pulse is applied. Exemplary embodiments may also include an apparatus with a controller coupled to an input node, a timer coupled to the controller, an inductive charger coupled to the controller, to an input node, and to an output node, and a sensor coupled to the controller and the output node. Exemplary embodiments may further include an apparatus where a sensor with a sampling capacitor has a first terminal coupled to the output node and a second terminal coupled to the controller and the inductive charger.

Abstract: Exemplary embodiments may include a method of applying a charging pulse to an output capacitor, detecting satisfaction of a charging threshold, ending the charging pulse in response to the detecting the satisfaction of the charging threshold, and discharging the sampling capacitor in response to the detecting the satisfaction of the charging threshold. In some embodiments, once a sampling capacitor voltage drops below a discharging threshold, a charging pulse is applied. Exemplary embodiments may also include an apparatus with a controller coupled to an input node, a timer coupled to the controller, an inductive charger coupled to the controller, to an input node, and to an output node, and a sensor coupled to the controller and the output node. Exemplary embodiments may further include an apparatus where a sensor with a sampling capacitor has a first terminal coupled to the output node and a second terminal coupled to the controller and the inductive charger.

Abstract: One embodiment pertains to a method including determining the duty cycle of a PWM signal, operating in valley current control mode when the duty cycle is greater than fifty percent, operating in peak current control mode when the duty cycle is less than fifty percent, and including, commencing a PWM pulse upon the occurrence of a pulse of a first clock signal pulse, and terminating the PWM pulse upon a level of a signal exceeding a positive window threshold.

Abstract: The present embodiments are directed to circuitry and techniques for operating a switching regulator, including in connection with transitions out of energy conservation modes during which a minimal amount of current is drawn from a power source such as a battery. According to certain aspects, embodiments of an energy conservation mode include provisions for maintaining high performance voltage regulation even in the face of a sudden increase in load requirements. These and other embodiments can further include various techniques for signaling an appropriate transition for exiting out of energy conservation mode and into a continuous conduction mode.

Abstract: One embodiment pertains to a method including determining the duty cycle of a PWM signal, operating in valley current control mode when the duty cycle is greater than fifty percent, operating in peak current control mode when the duty cycle is less than fifty percent, and including, commencing a PWM pulse upon the occurrence of a pulse of a first clock signal pulse, and terminating the PWM pulse upon a level of a signal exceeding a positive window threshold.

Abstract: One embodiment pertains to a method including determining the duty cycle of a PWM signal, operating in valley current control mode when the duty cycle is greater than fifty percent, operating in peak current control mode when the duty cycle is less than fifty percent, and including, commencing a PWM pulse upon the occurrence of a pulse of a first clock signal pulse, and terminating the PWM pulse upon a level of a signal exceeding a positive window threshold.

Abstract: One embodiment pertains to a method including determining the duty cycle of a PWM signal, operating in valley current control mode when the duty cycle is greater than fifty percent, operating in peak current control mode when the duty cycle is less than fifty percent, and including, commencing a PWM pulse upon the occurrence of a pulse of a first clock signal pulse, and terminating the PWM pulse upon a level of a signal exceeding a positive window threshold.

Abstract: A showerhead assembly attached to a plumbing feature has a main body with a hollow body portion to receive incoming fluid. An outlet is formed on the bottom of the main body to release outgoing fluid, and a fluid distributing element is configured to distribute the outgoing fluid from the hollow body portion. A main sprinkler unit is mounted below the main body to connect to the outlet to receive the incoming fluid, and a plurality of fluid release points formed on the bottom for emitting fluid. Several fluid distributing plates have connectors extended from each of them to connect to the fluid distributing element for receiving fluid from the hollow body portion, and several fluid release points are formed on the bottom of the fluid distributing plate for emitting fluid. The watering area can be adjusted by extending the fluid distributing plates as required, which enables a wide variation in spray patterns flowing from the showerhead assembly.