Patents by Inventor Daniela C. Zarnescu

Daniela C. Zarnescu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEUROPROTECTIVE COMPOUNDS AND METHODS OF USE
    Publication number: 20220031659
    Abstract: The present disclosure relates to methods treating a clinical condition associated with a neurodegenerative disease or locomotor dysfunction in a subject. In particular, methods include administering to the subject in need of such a treatment a therapeutically effective amount of a compound of the formula: or a pharmaceutically acceptable salt thereof, or a prodrug thereof, where X, Ra, Rb, R1, R2, R3, R4, and R5 are those defined herein.
    Type: Application
    Filed: October 18, 2021
    Publication date: February 3, 2022
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Jon T. Njardarson, Isaac Chogii, David Townsend Smith, Edon Vitaku, Daniela C. Zarnescu, Rachel Allen
  • Neuroprotective compounds and methods of use
    Patent number: 11147795
    Abstract: The present invention provides compounds and methods for mitigating a clinical condition associated with a neurodegenerative disease or a locomotor dysfunction in a subject. In one particular aspect, the invention relates to compounds and methods for reducing TDP-43 aggregation or toxicity in a subject.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: October 19, 2021
    Assignee: Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Jon T. Njardarson, Isaac Chogii, David Townsend Smith, Edon Vitaku, Daniela C. Zarnescu
  • NEUROPROTECTIVE COMPOUNDS AND METHODS OF USE
    Publication number: 20190350902
    Abstract: The present invention provides compounds and methods for mitigating a clinical condition associated with a neurodegenerative disease or a locomotor dysfunction in a subject. In one particular aspect, the invention relates to compounds and methods for reducing TDP-43 aggregation or toxicity in a subject.
    Type: Application
    Filed: July 18, 2019
    Publication date: November 21, 2019
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Jon T. Njardarson, Isaac Chogii, David Townsend Smith, Edon Vitaku, Daniela C. Zarnescu