Patents by Inventor Daniela Carnevale

Daniela Carnevale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant melusin fusion protein as pharmacological agent in the treatment of heart pathologies
    Patent number: 8658598
    Abstract: A recombinant melusin fusion protein having an improved stability and a capability to reach intracellular compartments as compared to recombinant melusin in vivo, wherein said protein comprises i) a human melusin protein having the amino acid sequence as defined in SEQ ID No.:1, or a homologue thereof having at least 60%, preferably at least 80%, more preferably at least 90% sequence identity to SEQ ID No.:1 and having the function of native melusin protein or a human melusin portion derived from SEQ ID No.:1 or homologue thereof having at least 60%, preferably at least 80%, more preferably at least 90% sequence identity of the melusin portion derived from SEQ ID No.:1 and having the function of native melusin protein and ii) a cell penetrating polypeptide.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: February 25, 2014
    Assignee: Target Heart Biotec S.R.L.
    Inventors: Féderica Accornero, Mara Brancaccio, Guido Tarone, Giuseppe Lembo, Daniela Carnevale
  • RECOMBINANT MELUSIN FUSION PROTEIN AS PHARMACOLOGICAL AGENT IN THE TREATMENT OF HEART PATHOLOGIES AND COMPOSITIONS THEREOF
    Publication number: 20120010386
    Abstract: A recombinant melusin fusion protein having an improved stability and a capability to reach intracellular compartments as compared to recombinant melusin in vivo, wherein said protein comprises i) a human melusin protein having the amino acid sequence as defined in SEQ ID No.:1, or a homologue thereof having at least 60%, preferably at least 80%, more preferably at least 90% sequence identity to SEQ ID No.:1 and having the function of native melusin protein or a human melusin portion derived from SEQ ID No.:1 or homologue thereof having at least 60%, preferably at least 80%, more preferably at least 90% sequence identity of the melusin portion derived from SEQ ID No.:1 and having the function of native melusin protein and ii) a cell penetrating polypeptide.
    Type: Application
    Filed: May 12, 2011
    Publication date: January 12, 2012
    Applicant: Target Heart Biotec S.r.l.
    Inventors: Federica Accornero, Mara Brancaccio, Guido Tarone, Giuseppe Lembo, Daniela Carnevale