Patents by Inventor Daniela Fischer
Daniela Fischer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10636589Abstract: A switching device includes a base module equipped with an electromagnetic drive that has a yoke, a coil and an armature arranged movably relative to the yoke, and that has a switching contact that includes a stationary switching piece and a movable switching piece arranged opposite the stationary switching piece, wherein the switching contact is switchable between an “open” position and a “closed” position via movement of the armature, where the switching device also includes a modular auxiliary switching unit equipped with a contact system that consists of a stationary switching piece and a movable switching piece arranged opposite the stationary switching piece such that the coupling between the base module and the modular auxiliary switching unit is configured such that different distances in the contact system of the auxiliary switching unit are transferrable during a trigger event via an elastic element regardless of the auxiliary switching unit in use.Type: GrantFiled: July 10, 2015Date of Patent: April 28, 2020Assignee: Siemens AktiengesellschaftInventors: Daniela Fischer, Josef Graf, Alexander Oberleiter, Norbert Zimmermann
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Publication number: 20170287652Abstract: A switching device includes a base module equipped with an electromagnetic drive that has a yoke, a coil and an armature arranged movably relative to the yoke, and that has a switching contact that includes a stationary switching piece and a movable switching piece arranged opposite the stationary switching piece, wherein the switching contact is switchable between an “open” position and a “closed” position via movement of the armature, where the switching device also includes a modular auxiliary switching unit equipped with a contact system that consists of a stationary switching piece and a movable switching piece arranged opposite the stationary switching piece such that the coupling between the base module and the modular auxiliary switching unit is configured such that different distances in the contact system of the auxiliary switching unit are transferrable during a trigger event via an elastic element regardless of the auxiliary switching unit in use.Type: ApplicationFiled: July 10, 2015Publication date: October 5, 2017Applicant: Siemens AktiengesellschaftInventors: Daniela FISCHER, Josef GRAF, Alexander OBERLEITER, Norbert ZIMMERMANN
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Patent number: 9692221Abstract: An electrical junction box includes a casing, a first installation space, a second installation space, and a connection part arranged in the casing the connection part includes a main body, a first connection end, and a second connection end. The main body is used for connecting to a cable; the first connection end, connected to the main body, is located in the first installation space, and is used for connecting to a contactor; and the second connection end, arranged on the first connection end, is located in the second installation space, and may be used for connecting to a resistance wire. The resistance wire may be connected to the second connection end without passing over the junction box, which is not only advantageous for fastening and installing the junction box, but also facilitates the connection and installation of the cable.Type: GrantFiled: July 13, 2012Date of Patent: June 27, 2017Assignee: SIEMENS AKTIENGESELLSCHAFTInventors: Daniela Fischer, Bing Han, Ai Xia Shen, Long Tao Wang, Nan Yu
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Publication number: 20160264935Abstract: The present disclosure provides transformed human pluripotent stem cell (t-hPSC). t-hPSCs are not dependent on Oct4 for renewal and survival, however exhibit a sensitivity to reduced levels of the transcription factor Nanog. Also provided are methods of culturing cells for use in a cell-based screening assay comprising placing one or more transformed human pluripotent stem cells into a receptacle and culturing said stem cells in the receptacle to form a monolayer of stem cells without cell overlap. Methods of screening compounds using t-hPSCs are also described.Type: ApplicationFiled: May 25, 2016Publication date: September 15, 2016Inventors: Mickie Bhatia, Tamra Werbowetski-Ogilvie, Eleftherios Sachlos, Daniela Fischer Russell, Sarah Laronde, JungBok Lee, Eva Szabo, Ruth Risueno
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Patent number: 9365821Abstract: The present disclosure provides transformed human pluripotent stem cell (t-hPSC). t-hPSCs are not dependent on Oct4 for renewal and survival, however exhibit a sensitivity to reduced levels of the transcription factor Nanog. Also provided are methods of culturing cells for use in a cell-based screening assay comprising placing one or more transformed human pluripotent stem cells into a receptacle and culturing said stem cells in the receptacle to form a monolayer of stem cells without cell overlap. Methods of screening compounds using t-hPSCs are also described.Type: GrantFiled: July 11, 2014Date of Patent: June 14, 2016Assignee: MCMASTER UNIVERSITYInventors: Mickie Bhatia, Tamra Werbowetski-Ogilvie, Eleftherios Sachlos, Daniela Fischer Russell, Sarah Laronde, JungBok Lee, Eva Szabo, Ruth Risueno
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Publication number: 20150318681Abstract: An electrical junction box includes a casing, a first installation space, a second installation space, and a connection part arranged in the casing the connection part includes a main body, a first connection end, and a second connection end. The main body is used for connecting to a cable; the first connection end, connected to the main body, is located in the first installation space, and is used for connecting to a contactor; and the second connection end, arranged on the first connection end, is located in the second installation space, and may be used for connecting to a resistance wire. The resistance wire may be connected to the second connection end without passing over the junction box, which is not only advantageous for fastening and installing the junction box, but also facilitates the connection and installation of the cable.Type: ApplicationFiled: July 13, 2012Publication date: November 5, 2015Applicant: SIEMENS AKTIENGESELLSCHAFTInventors: Daniela FISCHER, Bing HAN, Ai Xia SHEN, Long Tao WANG, Nan YU
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Publication number: 20150038371Abstract: The present disclosure provides transformed human pluripotent stem cell (t-hPSC). t-hPSCs are not dependent on Oct4 for renewal and survival, however exhibit a sensitivity to reduced levels of the transcription factor Nanog. Also provided are methods of culturing cells for use in a cell-based screening assay comprising placing one or more transformed human pluripotent stem cells into a receptacle and culturing said stem cells in the receptacle to form a monolayer of stem cells without cell overlap. Methods of screening compounds using t-hPSCs are also described.Type: ApplicationFiled: July 11, 2014Publication date: February 5, 2015Inventors: Mickie Bhatia, Tamra Werbowetski-Ogilvie, Eleftherios Sachlos, Daniela Fischer Russell, Sarah Laronde, JungBok Lee, Eva Szabo, Ruth Risueno
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Publication number: 20120252697Abstract: The present disclosure provides transformed human pluripotent stem cell (t-hPSC). t-hPSCs are not dependent on Oct4 for renewal and survival, however exhibit a sensitivity to reduced levels of the transcription factor Nanog. Also provided are methods of culturing cells for use in a cell-based screening assay comprising placing one or more transformed human pluripotent stem cells into a receptacle and culturing said stem cells in the receptacle to form a monolayer of stem cells without cell overlap. Methods of screening compounds using t-hPSCs are also described.Type: ApplicationFiled: September 1, 2010Publication date: October 4, 2012Applicant: Mcmaster UniversityInventors: Mickie Bhatia, Tamra Werbowetski-Ogilvie, Eleftherios Sachlos, Daniela Fischer Russell, Sarah Laronde, JungBok Lee, Eva Szabo, Ruth M. Risueno
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Patent number: 7612250Abstract: A nuclear transfer embryo is formed by destabilizing microtubules of an oocyte, whereby essentially all endogenous chromatin collects at a second polar body during meiosis of an oocyte. The oocyte is fused with the nucleus of a donor somatic cell of the same species of said oocyte prior to cessation of extrusion of the second polar body from the oocyte, thereby forming the nuclear transfer embryo. In one embodiment, the nuclear transfer embryo is employed to impregnate an animal, such as a mammal. In another embodiment, the donor nucleus is transgenic.Type: GrantFiled: July 29, 2002Date of Patent: November 3, 2009Assignee: Trustees of Tufts CollegeInventors: Eric W. Overstrom, Daniela Fischer Russell
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Patent number: 7028751Abstract: A cooling system includes a radial fan rotatable by an axis to deliver radial air flow to the cooling system, a plurality of heat exchangers spaced radially from the fan and arranged around the fan in a box-like configuration to receive the radial air flow therefrom, with the heat exchangers bounding an interior space of the cooling system. One of the heat exchangers is provided in the form of a charge air cooler that includes a first flow path for a charge air flow in heat exchange relation with a second flow path for an engine coolant flow of the vehicle. The cooling system further includes a surface associated with the charge air cooler to substantially block the radial air flow from exiting the interior space through the charge air cooler.Type: GrantFiled: April 25, 2002Date of Patent: April 18, 2006Assignee: Modine Manufacturing CompanyInventors: Daniela Fischer, Wolfgang Knecht, Werner Zobel, Mark Reichler, Jörg Soldner
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Patent number: 6779591Abstract: A heat exchanger including a first header having an inlet therein, a second header, an outlet in one of the first and second headers, and a plurality of flat tubes extending between the first and second headers for carrying a fluid between the first and second headers. A first connector is also provided for connecting a first exterior line to one of the first and second headers, the first connector being proximate and substantially parallel to an end of one of the flat tubes. In a compact cooling system, such heat exchangers may be disposed about a radial fan directing air flow outwardly away from the fan axis. One of a system inlet and a system outlet are connected via the first exterior lines to the first connectors of at least two of the heat exchangers.Type: GrantFiled: August 14, 2001Date of Patent: August 24, 2004Assignee: Modine Manufacturing CompanyInventors: Michael Ehlers, Wolfgang Knecht, Daniela Fischer, Roland Strähle, Jörg Soldner, Werner Zobel, Mark G. Voss, Frank Vetter
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Patent number: 6749007Abstract: A compact cooling system including a radial fan directing air flow outwardly and a plurality of heat exchangers disposed around the radial fan. Each heat exchanger has a plurality of tubes extending between an inlet header and an outlet header, with the headers extending generally in the same direction as the fan axis. A system inlet is connected to the inlet headers and a system outlet is connected to the outlet headers, whereby the length of the connection between each heat exchanger and the system outlet and system inlet is generally the same for each heat exchanger.Type: GrantFiled: July 24, 2001Date of Patent: June 15, 2004Assignee: Modine Manufacturing CompanyInventors: Michael Ehlers, Wolfgang Knecht, Daniela Fischer, Roland Strähle, Jörg Soldner, Werner Zobel
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Publication number: 20040019924Abstract: A nuclear transfer embryo is formed by destabilizing microtubules of an oocyte, whereby essentially all endogenous chromatin collects at a second polar body during meiosis of an oocyte. The oocyte is fused with the nucleus of a donor somatic cell of the same species of said oocyte prior to cessation of extrusion of the second polar body from the oocyte, thereby forming the nuclear transfer embryo. In one embodiment, the nuclear transfer embryo is employed to impregnate an animal, such as a mammal. In another embodiment, the donor nucleus is transgenic.Type: ApplicationFiled: July 29, 2002Publication date: January 29, 2004Applicant: The Trustees of Tufts CollegeInventors: Eric W. Overstrom, Daniela Fischer
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Publication number: 20020189786Abstract: A cooling system includes a radial fan rotatable by an axis to deliver radial air flow to the cooling system, a plurality of heat exchangers spaced radially from the fan and arranged around the fan in a box-like configuration to receive the radial air flow therefrom, with the heat exchangers bounding an interior space of the cooling system. One of the heat exchangers is provided in the form of a charge air cooler that includes a first flow path for a charge air flow in heat exchange relation with a second flow path for an engine coolant flow of the vehicle. The cooling system further includes a surface associated with the charge air cooler to substantially block the radial air flow from exiting the interior space through the charge air cooler.Type: ApplicationFiled: April 25, 2002Publication date: December 19, 2002Inventors: Daniela Fischer, Wolfgang Knecht, Werner Zobel, Mark Reichler, Jorg Soldner
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Publication number: 20020152766Abstract: A box-like cooling system (10) is provided for use in a vehicle. The system (10) include a plurality of heat exchangers (16, 18, 20) in a box-like arrangement around a radial fan (12) that directs a radial air flow through the cores (42) of the heat exchangers (16, 18, 20). The system (10) includes a front wall (22) having an inlet opening (60) for the air flow drawn by the fan (12), and a plurality of dynamic air flow ports (66) that are closed when the fan (12) is in an operating state providing the radial cooling air flow to the heat exchangers (16, 18, 20), and are open when the fan (12) is in a non-operating state and there is a dynamic air pressure on the front wall (22) produced by forward movement of the vehicle so as to allow a cooling air flow through the ports (66) into interior space (26) of the cooling system (10) and then through the cores (42) of the heat exchangers (16, 18, 20).Type: ApplicationFiled: April 8, 2002Publication date: October 24, 2002Inventors: Daniela Fischer, Wolfgang Knecht, Werner Zobel
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Publication number: 20020023730Abstract: A heat exchanger including a first header having an inlet therein, a second header, an outlet in one of the first and second headers, and a plurality of flat tubes extending between the first and second headers for carrying a fluid between the first and second headers. A first connector is also provided for connecting a first exterior line to one of the first and second headers, the first connector being proximate and substantially parallel to an end of one of the flat tubes. In a compact cooling system, such heat exchangers may be disposed about a radial fan directing air flow outwardly away from the fan axis. One of a system inlet and a system outlet are connected via the first exterior lines to the first connectors of at least two of the heat exchangers. 655.Type: ApplicationFiled: August 14, 2001Publication date: February 28, 2002Inventors: Michael Ehlers, Wolfgang Knecht, Daniela Fischer, Roland Strahle, Jorg Soldner, Werner Zobel, Mark G. Voss, Frank Vetter
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Publication number: 20020023738Abstract: A compact cooling system including a radial fan directing air flow outwardly and a plurality of heat exchangers disposed around the radial fan. Each heat exchanger has a plurality of tubes extending between an inlet header and an outlet header, with the headers extending generally in the same direction as the fan axis. A system inlet is connected to the inlet headers and a system outlet is connected to the outlet headers, whereby the length of the connection between each heat exchanger and the system outlet and system inlet is generally the same for each heat exchanger.Type: ApplicationFiled: July 24, 2001Publication date: February 28, 2002Inventors: Michael Ehlers, Wolfgang knecht, Daniela Fischer, Roland Strahle, Jorg Soldner, Werner Zobel