Patents by Inventor Daniela Ghisotti

Daniela Ghisotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Catalyzing transglycosylation using a recombinant host cell overexpressing uridine phosphorylase and purine nucleoside phosphorylase
    Patent number: 7781189
    Abstract: Novel strains of genetically modified prokaryotic micro-organisms capable of expressing polypeptides having the enzyme activity of the enzymes uridine phosphorylase (UdP) and purine nucleoside phosphorylase (PNP) are described; the strains in question can be used, both in the form of whole cells and in the form of crude or purified extracts, to catalyse transglycosylation reactions between a donor nucleoside and an acceptor base with particularly high yields. The associated plasmid vectors are also described.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: August 24, 2010
    Assignee: Bio-Ker S.R.L.
    Inventors: Giuseppina Bestetti, Simona Cali, Daniela Ghisotti, Gaetano Orsini, Giancarlo Tonon, Gabriele Zuffi
  • Vectors, host cells, and methods for production of uridine phosphorylase and purine nucleotide phosphorylase
    Publication number: 20050142645
    Abstract: Novel strains of genetically modified prokaryotic micro-organisms capable of expressing polypeptides having the enzyme activity of the enzymes uridine phosphorylase (UdP) and purine nucleoside phosphorylase (PNP) are described; the strains in question can be used, both in the form of whole cells and in the form of crude or purified extracts, to catalyse transglycosylation reactions between a donor nucleoside and an acceptor base with particularly high yields. The associated plasmid vectors are also described.
    Type: Application
    Filed: January 14, 2005
    Publication date: June 30, 2005
    Applicant: Keryos SPA
    Inventors: Giuseppina Bestetti, Simona Cali, Daniela Ghisotti, Gaetano Orsini, Giancarlo Tonon, Gabriele Zuffi
  • Vectors, host cells, and methods for production of uridine phosphorylase and purine nucleoside phosphorylase
    Patent number: 6911341
    Abstract: Strains of genetically modified prokaryotic micro-organisms capable of expressing polypeptides having the enzyme activity of the enzymes uridine posphorylase (UdP) and purine nucleoside phosphorylase (PNP) are described; the strains in question can be used, both in the form of whole cells and in the form of crude or purified extracts, to catalyse transglycosylation reactions between a donor nucleoside and an acceptor base with particularly high yields. The associated plasmid vectors are also described.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: June 28, 2005
    Assignee: Keryos SpA
    Inventors: Giuseppina Bestetti, Simona Cali' , Daniela Ghisotti, Gaetano Orsini, Giancarlo Tonon, Gabriele Zuffi
  • Recombinant bacterial strains for the production of natural nucleosides and modified analogues thereof
    Publication number: 20030059870
    Abstract: Strains of genetically modified prokaryotic micro-organisms capable of expressing polypeptides having the enzyme activity of the enzymes uridine posphorylase (UdP) and purine nucleoside phosphorylase (PNP) are described; the strains in question can be used, both in the form of whole cells and in the form of crude or purified extracts, to catalyse transglycosylation reactions between a donor nucleoside and an acceptor base with particularly high yields. The associated plasmid vectors are also described.
    Type: Application
    Filed: June 25, 2001
    Publication date: March 27, 2003
    Inventors: Giuseppina Bestetti, Simona Cali', Daniela Ghisotti, Gaetano Orsini, Giancarlo Tonon, Gabriele Zuffi