Patents by Inventor Daniela Keilberg

Daniela Keilberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteins for the treatment of epithelial barrier function disorders
    Patent number: 11505583
    Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: November 22, 2022
    Assignee: Second Genome, Inc.
    Inventors: Cristina N. Butterfield, Daniela Keilberg, Andrew W. Goodyear, Andrew W. Han
  • LACTOCOCCUS LACTIS EXPRESSION SYSTEM FOR DELIVERING PROTEINS EFFICACIOUS FOR THE TREATMENT OF EPITHELIAL BARRIER FUNCTION DISORDERS
    Publication number: 20210380994
    Abstract: The disclosure relates to live biotherapeutic products, probiotics, and therapeutic composition comprising said probiotics having therapeutic proteins, and methods of using them to treat various human diseases. In particular aspects, the disclosure provides such compositions comprising strains of the Lactococcus lacus bacterium within which said therapeutic protein are present. The disclosed pharmaceutical compositions are useful for treating gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity, especially, for treating or preventing various types of mucositis.
    Type: Application
    Filed: October 9, 2019
    Publication date: December 9, 2021
    Inventors: Michi Izumi Willcoxon, Daniela Keilberg, Andrew Wonhee Han, Andrew W. Goodyear
  • Proteins for the Treatment of Epithelial Barrier Function Disorders
    Publication number: 20210230236
    Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: April 8, 2019
    Publication date: July 29, 2021
    Inventors: Cristina N. Butterfield, Daniela Keilberg, Andrew W. Goodyear, Andrew W. Han