Patents by Inventor Daniela Paulsen

Daniela Paulsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PARAPOXVIRUS FOR CONDITIONING FOR AND TREATMENT OF CORONAVIRUS INFECTIONS
    Publication number: 20220401553
    Abstract: The present invention relates to the treatment of coronavirus infections and to preparing subjects for such an infection by administering a parapoxvirus. This treatment is to assist the immune system in combatting the virus and to thereby prevent and to ameliorate symptoms of coronavirus disease.
    Type: Application
    Filed: May 10, 2021
    Publication date: December 22, 2022
    Inventors: Daniela Paulsen, Alexander Birkmann, Peter Lischka, Tamara Pfaff, Holger Zimmermann
  • Combination Therapies of Hepatitis B Virus (HBV)-infected individuals using Parapoxvirus Ovis (PPVO) and at Least one Further Antiviral Drug
    Publication number: 20200261520
    Abstract: The present invention relates to new combination therapies of HBV-infected individuals using a Parapoxvirus ovis (PPVO) and at least one further antiviral drug, e.g., nucleoside inhibitors, such as Entecavir. The methods and combination products according to the present invention are safe and suitable for the induction of a functional cure in chronically HBV-infected patients.
    Type: Application
    Filed: September 7, 2018
    Publication date: August 20, 2020
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Daniela PAULSEN, Andreas URBAN, Ibironke ADDY, Tamara PFAFF, Stephan MENNE, Willem SLOOT
  • Agent for the treatment and or prophylaxis of an autoimmune disease and for the formation of regulatory T cells
    Patent number: 10086046
    Abstract: The present invention relates to an agent for the treatment and/or prophylaxis of an autoimmune disease, an agent for the formation of regulatory T cells (TReg) in an organism and various methods in which the agents according to the invention are used.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: October 2, 2018
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Daniela Paulsen, Nina Brunner, Dorothy Bray
  • AGENT FOR THE TREATMENT AND OR PROPHYLAXIS OF AN AUTOIMMUNE DISEASE AND FOR THE FORMATION OF REGULATORY T CELLS
    Publication number: 20170173117
    Abstract: The present invention relates to an agent for the treatment and/or prophylaxis of an autoimmune disease, an agent for the formation of regulatory T cells (TReg) in an organism and various methods in which the agents according to the invention are used.
    Type: Application
    Filed: February 22, 2017
    Publication date: June 22, 2017
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Daniela PAULSEN, Nina BRUNNER, Dorothy BRAY
  • AGENT FOR THE TREATMENT AND OR PROPHYLAXIS OF AN AUTOIMMUNE DISEASE AND FOR THE FORMATION OF REGULATORY T CELLS
    Publication number: 20170165326
    Abstract: The present invention relates to an agent for the treatment and/or prophylaxis of an autoimmune disease, an agent for the formation of regulatory T cells (TReg) in an organism and various methods in which the agents according to the invention are used.
    Type: Application
    Filed: February 22, 2017
    Publication date: June 15, 2017
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Daniela PAULSEN, Nina BRUNNER, Dorothy BRAY
  • Agent for the treatment and/or prophylaxis of an autoimmune disease and for the formation of regulatory T cells
    Patent number: 9616105
    Abstract: The present invention relates to an agent for the treatment and/or prophylaxis of an autoimmune disease, an agent for the formation of regulatory T cells (TReg) in an organism and various methods in which the agents according to the invention are used.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: April 11, 2017
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Daniela Paulsen, Nina Brunner, Dorothy Bray
  • AGENT FOR THE TREATMENT AND/OR PROPHYLAXIS OF AN AUTOIMMUNE DISEASE AND FOR THE FORMATION OF REGULATORY T CELLS
    Publication number: 20150374788
    Abstract: The present invention relates to an agent for the treatment and/or prophylaxis of an autoimmune disease, an agent for the formation of regulatory T cells (TReg) in an organism and various methods in which the agents according to the invention are used.
    Type: Application
    Filed: June 26, 2015
    Publication date: December 31, 2015
    Inventors: Daniela PAULSEN, Nina BRUNNER, Dorothy BRAY
  • Substituted (thiazolyl-carbonyl)imidazolidinones and use thereof
    Patent number: 8575357
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: November 5, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Kersten Matthias Gericke, Steffen Wildum, Daniela Paulsen
  • Substituted (thiophenyl-carbonyl)imidazolidinones, and use thereof
    Patent number: 8546438
    Abstract: The present invention relates to novel substituted (thiophenyl-carbonyl)imidazolidinones, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: October 1, 2013
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • Substituted (pyrazolylcarbonyl)imidazolidinones and their use
    Patent number: 8399682
    Abstract: The present invention relates to novel substituted (pyrazolylcarbonyl)imidazolidinones, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: March 19, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF
    Publication number: 20130045999
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: February 17, 2012
    Publication date: February 21, 2013
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Kersten Matthias Gericke, Steffen Wildum, Daniela Paulsen
  • Parapoxviruses in combination with other antiviral agents for the treatment of viral diseases
    Patent number: 8343478
    Abstract: The present invention relates to the use of Parapoxviruses in combination with other agents for the treatment of viral diseases, and in particular HIV infections and AIDS. The invention also relates to methods for producing medicaments based on combinations of Parapoxviruses and other antiviral agents, and to such medicaments. In particular, the invention relates to the use of Parapoxviruses in combination with agents of the kind used for antiretroviral therapy and highly active antiretroviral therapy (HAART).
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: January 1, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Daniela Paulsen, Helga Ruebsamen-Schaeff, Amar Kureishi, Gerhard Hunsmann, Christiane Stahl-Hennig, Andreas Meyerhans, Alexandra Schuetz, Olaf Weber
  • Substituted furancarboxamides, and use thereof
    Patent number: 8324268
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: December 4, 2012
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • Substituted arylsulfonamides as antiviral agents
    Patent number: 8318761
    Abstract: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: November 27, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Niels Svenstrup, Holger Zimmermann, Dagmar Karthaus, Andreas Goeller, Dirk Heimbach, Kerstin Henninger, Dieter Lang, Daniela Paulsen, Bernd Riedl, Rudolf Schohe-Loop, Joachim Schuhmacher, Tobias Wunberg
  • Substituted pyrazolamides and their use
    Patent number: 8314089
    Abstract: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: November 20, 2012
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Rudolf Schohe-Loop, Reinhold Welker, Arnold Paessens, Marcus Bauser, Friederike Stoll, Frank Dittmer, Kerstin Henninger, Daniela Paulsen, Dieter Lang
  • SUBSTITUTED FURANCARBOXAMIDES, AND USE THEREOF
    Publication number: 20120022059
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 26, 2012
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • SUBSTITUTED (THIOPHENYL-CARBONYL)IMIDAZOLIDINONES, AND USE THEREOF
    Publication number: 20120022123
    Abstract: The present invention relates to novel substituted (thiophenyl-carbonyl)imidazolidinones, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 26, 2012
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne GRESCHAT, Steffen WILDUM, Daniela PAULSEN
  • SUBSTITUTED PYRAZOLAMIDES AND THEIR USE
    Publication number: 20110172207
    Abstract: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: September 16, 2010
    Publication date: July 14, 2011
    Applicant: AiCuris Gmbh & Co. KG
    Inventors: Rudolf SCHOHE-LOOP, Reinhold Welker, Arnold Paessens, Marcus Bauser, Friederike Stoll, Frank Dittmer, Kerstin Henninger, Daniela Paulsen, Dieter Lang
  • AGENT FOR THE TREATMENT AND/OR PROPHYLAXIS OF AN AUTOIMMUNE DISEASE AND FOR THE FORMATION OF REGULATORY T CELLS
    Publication number: 20110150826
    Abstract: The present invention relates to an agent for the treatment and/or prophylaxis of an autoimmune disease, an agent for the formation of regulatory T cells (TReg) in an organism and various methods in which the agents according to the invention are used.
    Type: Application
    Filed: November 8, 2010
    Publication date: June 23, 2011
    Inventors: Daniela Paulsen, Nina Brunner, Dorothy Bray
  • SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE
    Publication number: 20110124618
    Abstract: The present invention relates to novel substituted (pyrazolylcarbonyl)imidazolidinones, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: September 17, 2010
    Publication date: May 26, 2011
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne GRESCHAT, Steffen WILDUM, Daniela PAULSEN