Patents by Inventor Daniela Rebolledo LOPEZ

Daniela Rebolledo LOPEZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEINS FOR TARGETING NEURONAL NITRIC OXIDE SYNTHASE TO MUSCLE SARCOLEMMA AND RELATED METHODS OF USE
    Publication number: 20160220647
    Abstract: It is demonstrated herein that nNOS-? is an important modulator of muscle function, and that the loss of nNOS-? contributes to pathogenesis in neuromuscular diseases, including DMD. Furthermore, the impact of the restoration of cytoplasmic and sarcolemma-localized nNOS-? on mdx skeletal muscle pathology and function is demonstrated. Accordingly, provided herein are compositions, including therapeutic and pharmaceutical compositions, comprising nNOS-? fusion proteins and derivatives thereof, and methods of treating neuromuscular disorders using such nNOS-? fusion proteins.
    Type: Application
    Filed: September 9, 2014
    Publication date: August 4, 2016
    Applicant: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Stanley C. FROEHNER, Marvin ADAMS, Min Jeong KIM, Daniela Rebolledo LOPEZ, Nicholas P. WHITEHEAD