Patents by Inventor Daniela Rinaudo

Daniela Rinaudo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carrier molecule for antigens
    Patent number: 10245310
    Abstract: The invention provides a conjugate comprising an antigen and a carrier molecule, wherein the carrier molecule comprises a BP-2a antigen and a spb1 antigen. BP-2a and spb1 are Streptococcus agalactiae antigens. The conjugate may be used in a method for raising an immune response in a mammal, the method comprising administering the conjugate to the mammal. Also provided are pharmaceutical compositions, particularly vaccines, comprising the conjugate.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: April 2, 2019
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: Francesco Berti, Roberta Cozzi, Domenico Maione, Cira Daniela Rinaudo, Immaculada Margarit Y Ros, Guido Grandi
  • Immunogenic proteins and compositions
    Patent number: 10086060
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS).
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: October 2, 2018
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • Immunogenic Proteins and Compositions
    Publication number: 20170296645
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS)
    Type: Application
    Filed: June 22, 2017
    Publication date: October 19, 2017
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • CARRIER MOLECULE FOR ANTIGENS
    Publication number: 20170224803
    Abstract: The invention provides a conjugate comprising an antigen and a carrier molecule, wherein the carrier molecule comprises a BP-2a antigen and a spb1 antigen. BP-2a and spb1 are Streptococcus agalactiae antigens. The conjugate may be used in a method for raising an immune response in a mammal, the method comprising administering the conjugate to the mammal. Also provided are pharmaceutical compositions, particularly vaccines, comprising the conjugate.
    Type: Application
    Filed: August 5, 2015
    Publication date: August 10, 2017
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Francesco BERTI, Roberta COZZI, Domenico MAIONE, Cira Daniela RINAUDO, Immaculada MARGARIT Y ROS, Guido GRANDI
  • Immunogenic proteins and compositions
    Patent number: 9725488
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS).
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: August 8, 2017
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • Immunogenic Proteins and Compositions
    Publication number: 20160362457
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS)
    Type: Application
    Filed: August 31, 2016
    Publication date: December 15, 2016
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • Immunogenic proteins and compositions
    Patent number: 9458229
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS).
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: October 4, 2016
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • IMMUNOGENIC PROTEINS AND COMPOSITIONS
    Publication number: 20150343051
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS).
    Type: Application
    Filed: February 25, 2015
    Publication date: December 3, 2015
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • PILUS PROTEINS AND COMPOSITIONS
    Publication number: 20150273042
    Abstract: The invention provides methods of forming pili in vitro and proteins suitable for use in these methods. The invention also provides pili produced by these methods and compositions comprising these pili for the treatment and prevention of bacterial disease, in particular of conditions caused by Streptococcus.
    Type: Application
    Filed: February 23, 2013
    Publication date: October 1, 2015
    Inventors: Domenico Maione, Immaculada Margarit Y Ros, Roberta Cozzi, Cira Daniela Rinaudo, Maddalena Lazzarin, Francesca Zerbini
  • Immunogenic proteins and compositions for the treatment and prevention of
    Patent number: 9079946
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS).
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: July 14, 2015
    Assignee: Novartis AG
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • Immunogenic compositions for gram positive bacteria such as
    Patent number: 8778358
    Abstract: The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: July 15, 2014
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: John Telford, Guido Grandi, Immaculada Margarit Y Ros, Cira Daniela Rinaudo, Domenico Maione
  • IMMUNOGENIC PROTEINS AND COMPOSITIONS
    Publication number: 20130216568
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS).
    Type: Application
    Filed: February 28, 2011
    Publication date: August 22, 2013
    Inventors: Domenico Maione, Cira Daniela Rinaudo
  • IMMUNOGENIC PROTEINS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF STREPTOCOCCUS AGALACTIAE
    Publication number: 20130071416
    Abstract: The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS)
    Type: Application
    Filed: April 1, 2011
    Publication date: March 21, 2013
    Applicant: NOVARTIS AG
    Inventors: Guido Grandi, Domenico Maione, Cira Daniela Rinaudo
  • IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE
    Publication number: 20110110982
    Abstract: The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.
    Type: Application
    Filed: October 18, 2010
    Publication date: May 12, 2011
    Applicant: Novartis Vaccines and Diagnostics, Inc.
    Inventors: John Telford, Guido Grandi, Immaculada Margarit Y. Ros, Cira Daniela Rinaudo, Domenico Maione
  • IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA
    Publication number: 20100150943
    Abstract: The invention relates to the identification of a new adhesin islands within the genomes of several Gram positive Streptococcus serotypes and isolates. Adhesin island polypeptides of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS, GBS, and S. pneumococcal infections.
    Type: Application
    Filed: July 26, 2007
    Publication date: June 17, 2010
    Applicant: NOVARTIS AG
    Inventors: Guido Grandi, John Telford, Marirosa Mora, Cesira Galeotti, Daniela Rinaudo, Andrea Guido Oreste Manetti
  • Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
    Publication number: 20090317420
    Abstract: The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.
    Type: Application
    Filed: July 29, 2005
    Publication date: December 24, 2009
    Applicant: Chiron Corporation
    Inventors: John Telford, Guido Grandi, Peter Lauer, Marlrosa Mora, Immaculada Margarit Y Ros, Domenico Malone, Guiliano Bensi, Daniela Rinaudo, Vega Masignani, Michelle Barocchi, Rino Rappuloi
  • Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
    Publication number: 20060165716
    Abstract: The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.
    Type: Application
    Filed: July 29, 2005
    Publication date: July 27, 2006
    Inventors: John Telford, Guido Grandi, Peter Lauer, Marirosa Mora, Immaculada Y Ros, Domenico Maione, Guiliano Bensi, Daniela Rinaudo, Vega Masignani, Michelle Barocchi, Rino Rappuoli