Patents by Inventor Daniela Rotin

Daniela Rotin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treatment of cystic fibrosis and diseases associated with aberrant protein cellular processing
    Patent number: 9120768
    Abstract: The disclosure relates to resorcylic acid lactones and indolinone-containing compounds for use in treatment of diseases associated with aberrant protein processing, such as cystic fibrosis (CF; mucoviscidosis). The disclosure more generally relates to treatment of aberrant protein processing, such as errors in protein folding, trafficking or post-translational modification.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: September 1, 2015
    Assignee: The Hospital for Sick Children
    Inventors: Daniela Rotin, Agata Trzcinska-Daneluti
  • COMPOSITIONS AND METHODS FOR TREATMENT OF CYSTIC FIBROSIS AND DISEASES ASSOCIATED WITH ABERRANT PROTEIN CELLULAR PROCESSING
    Publication number: 20130150422
    Abstract: The disclosure relates to resorcylic acid lactones and indolinone-containing compounds for use in treatment of diseases associated with aberrant protein processing, such as cystic fibrosis (CF; mucoviscidosis). The disclosure more generally relates to treatment of aberrant protein processing, such as errors in protein folding, trafficking or post-translational modification.
    Type: Application
    Filed: August 19, 2011
    Publication date: June 13, 2013
    Applicant: THE HOSPITAL FOR SICK CHILDREN
    Inventors: Daniela Rotin, Agata Trzcinska-Daneluti
  • Ras activator nucleic acid molecules, polypeptides and methods of use
    Publication number: 20020143164
    Abstract: The invention is a GRF4 nucleic acid molecule and its corresponding protein which has an important role in cell signaling. The invention also includes biologically functional equivalent nucleic acid molecules and proteins. The invention also relates to methods of using these nucleic acid sequences and proteins in medical treatments and drug screening.
    Type: Application
    Filed: July 20, 2001
    Publication date: October 3, 2002
    Inventors: Daniela Rotin, Nam Pham