Patents by Inventor Daniela S.A. GOLTSMAN

Daniela S.A. GOLTSMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20240117330
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: June 15, 2023
    Publication date: April 11, 2024
    Inventors: Brian Thomas, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20240110167
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: October 17, 2023
    Publication date: April 4, 2024
    Inventors: Brian C. THOMAS, Christopher BROWN, Daniela S.A. GOLTSMAN, Cristina BUTTERFIELD, Lisa ALEXANDER, Cindy CASTELLE
  • Class II, type II CRISPR systems
    Patent number: 11946039
    Abstract: The present disclosure provides for endonuclease enzymes as well as methods of using such enzymes or variants thereof.
    Type: Grant
    Filed: July 5, 2022
    Date of Patent: April 2, 2024
    Assignee: Metagenomi, Inc.
    Inventors: Brian Thomas, Christopher Brown, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20240093239
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: April 18, 2023
    Publication date: March 21, 2024
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • SYSTEMS AND METHODS FOR TRANSPOSING CARGO NUCLEOTIDE SEQUENCES
    Publication number: 20230340481
    Abstract: The present disclosure provides systems and methods for transposing a cargo nucleotide sequence to a target nucleic acid site. These systems and methods may comprise a first double-stranded nucleic acid comprising the cargo nucleotide sequence, wherein the cargo nucleotide sequence is configured to interact with a recombinase complex, a cas effector complex comprising a cas effector and at least one engineered guide polynucleotide configured to hybridize to the target nucleic acid site, and the recombinase complex wherein said recombinase complex is configured to recruit the cargo nucleotide to the target nucleic acid site.
    Type: Application
    Filed: March 22, 2023
    Publication date: October 26, 2023
    Inventors: Brian THOMAS, Christopher BROWN, Daniela S.A. GOLTSMAN, Cristina BUTTERFIELD, Lisa ALEXANDER, Jason LIU
  • Class II, type V CRISPR systems
    Patent number: 11713471
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: August 1, 2023
    Assignee: METAGENOMI, INC.
    Inventors: Brian Thomas, Christopher Brown, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman, Justine Albers, Alan Brooks, Greg Cost, Morayma Temoche-Diaz, Cindy Castelle, Rebecca Lamothe
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20230227857
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: September 6, 2022
    Publication date: July 20, 2023
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine B. ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • CLASS II, TYPE II CRISPR SYSTEMS
    Publication number: 20230051396
    Abstract: The present disclosure provides for endonuclease enzymes as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: July 5, 2022
    Publication date: February 16, 2023
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20220298494
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: February 14, 2020
    Publication date: September 22, 2022
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20220290187
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: March 28, 2022
    Publication date: September 15, 2022
    Inventors: Brian C. THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine B. ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20220220460
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: August 13, 2021
    Publication date: July 14, 2022
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20220033791
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: March 5, 2021
    Publication date: February 3, 2022
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • Enzymes with RuvC domains
    Patent number: 10982200
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: April 20, 2021
    Assignee: METAGENOMI IP TECHNOLOGIES, LLC
    Inventors: Brian Thomas, Christopher Brown, Rose Kantor, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman, Jason Liu
  • Enzymes with RuvC domains
    Patent number: 10913941
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: February 9, 2021
    Assignee: METAGENOMI IP TECHNOLOGIES, LLC
    Inventors: Brian Thomas, Christopher Brown, Rose Kantor, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman, Jason Liu
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20200332274
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 22, 2020
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20200332273
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 22, 2020
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU