Patents by Inventor Daniela Ungureanu

Daniela Ungureanu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Identifying Janus Kinase (JAK) Modulators for Therapeutics
    Publication number: 20140286964
    Abstract: The present invention provides methods for designing agents such as ligands capable of binding to a Janus kinase (Jak), particularly a Jak2 JH2, and especially a JH2 V617F, screening methods for identifying agents such as ligands and small molecules capable of binding to the same, and computer assisted methods for designing and identifying such agents. Further, the present invention provides methods for treating myeloproliferative neoplasias (MPNs) along with agents such as ligands and small molecules identified or designed using the methods described.
    Type: Application
    Filed: October 24, 2012
    Publication date: September 25, 2014
    Inventors: Stevan R. Hubbard, Rajintha M. Bandarayanake, Olli Silvennoinen, Daniela Ungureanu
  • Dual activity kinase domains and uses thereof
    Patent number: 8841078
    Abstract: The present invention relates to a dual activity domain of JAK proteins, namely JH2. It is provided that the JH2 domain is a true and important target for drug development, especially for diseases caused by aberrant JAK signalling, such as myeloproliferative disorders and leukemias.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: September 23, 2014
    Assignee: Genon Biotechnologies Oy
    Inventors: Olli Silvennoinen, Daniela Ungureanu
  • DUAL ACTIVITY KINASE DOMAINS AND USES THEREOF
    Publication number: 20120309023
    Abstract: The present invention relates to a dual activity domain JAK proteins, namely JH2. It is provided that the JH2 domain is a true and important target for drug development, especially for diseases caused by aberrant JAK signalling, such as myeloproliferative disorders and leukemias.
    Type: Application
    Filed: February 10, 2011
    Publication date: December 6, 2012
    Applicant: GENON BIOTECHNOLOGIES OY
    Inventors: Olli Silvennoinen, Daniela Ungureanu