Abstract: The present invention relates to an antibody or an antigen binding fragment thereof that specifically binds to L1-CAM (CD171), to a polynucleotide encoding at least one variable heavy chain sequence and/or at least one variable light chain sequence as in the antibody or an antigen binding fragment thereof of the present invention, to a host cell comprising the polynucleotide of the present invention, to an immunoconjugate comprising an antibody or an antigen-fragment binding thereof of the present invention and an active agent, to a pharmaceutical composition comprising the antibody or the antigen-binding fragment thereof of the present invention, or the immunoconjugate of the present invention, and their use in treatment and/or diagnosis. The antibodies, antigen-binding fragments thereof, the immunoconjugates and the pharmaceutical compositions described herein are particularly useful in treatment or diagnosis of an L1-CAM (CD171) associated cancer.

Abstract: The invention relates to a method to regulate a circulating air and/or intake air portion (Vs, Vo) in a passenger compartment of a vehicle, in particular a motor vehicle, with a sensor for detecting hazardous gas concentrations in the passenger compartment and for supplying a triggering signal (1CO2) of a control unit for the circulating air and/or intake air portion (Vs, Vo) in a passenger compartment. To achieve air supply in a passenger compartment that does justice to demand and is optimized with respect to energy consumption, the sensor for detecting hazardous gas concentrations is a temperature-compensated sensor, whereby the sensor for detecting the ambient temperature along with the sensor for detecting the hazardous gas concentration supply signals (1t, 1CO2) for triggering a control unit for the circulating air and/or intake air portion (Vs, Vo).

Abstract: A method for implementing measures to avert danger for living beings in a compartment in a motor vehicle, in which a carbon dioxide variable describing the carbon dioxide content or the rate of increase of the carbon dioxide content of the air in this space is detected; and in which a temperature variable representing the room temperature in this space is determined. The temperature variable is compared to a temperature-threshold value, and in the event that the temperature variable exceeds a temperature threshold value, the danger-averting measures in response to the temperature threshold value being exceeded are implemented only if the carbon dioxide variable has exceeded a carbon dioxide threshold value.