Patents by Inventor Daniele Ghidoli
Daniele Ghidoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10532187Abstract: A steerable catheter is disclosed, having an elongated, tubular catheter body with at least one deflection member slidably disposed within a lumen, secured at a distal end to a tip section and terminating in an interconnect at a proximal end and a handle releasably attached to the proximal end of the catheter body. The handle has at least one sliding member coupled to an actuator, such that manipulation of the actuator causes relative longitudinal movement with respect to the handle, wherein the interconnect and the sliding member engage when the handle is attached to the catheter body so that the relative longitudinal movement of the sliding member is transmitted to the deflection member and wherein the interconnect and the sliding member disengage when the handle is released from the catheter body.Type: GrantFiled: October 17, 2017Date of Patent: January 14, 2020Assignee: Biosense Webster (Israel) Ltd.Inventors: Jeffrey Schultz, Corey Rousu, Daniele Ghidoli, Simon Jung, Jeffrey Clark
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Publication number: 20190184138Abstract: A deflectable catheter with biased deflection characteristics has an elongated catheter body having a micro-injection molded spine that is configured with a center core, outwardly extending opposing struts, and one or more sets of longitudinally-aligned and discrete fins, wherein the struts resist deflection of the spine in a first plane and bias deflection of the spine in a second plane, wherein parameters of the discrete fins define deflection characteristics of the spine in the second plane.Type: ApplicationFiled: December 15, 2017Publication date: June 20, 2019Inventors: Jeffrey William Schultz, Mark T. Stanley, Daniele Ghidoli
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Publication number: 20190111238Abstract: A steerable catheter is disclosed, having an elongated, tubular catheter body with at least one deflection member slidably disposed within a lumen, secured at a distal end to a tip section and terminating in an interconnect at a proximal end and a handle releasably attached to the proximal end of the catheter body. The handle has at least one sliding member coupled to an actuator, such that manipulation of the actuator causes relative longitudinal movement with respect to the handle, wherein the interconnect and the sliding member engage when the handle is attached to the catheter body so that the relative longitudinal movement of the sliding member is transmitted to the deflection member and wherein the interconnect and the sliding member disengage when the handle is released from the catheter body.Type: ApplicationFiled: October 17, 2017Publication date: April 18, 2019Inventors: Jeffrey Schultz, Corey Rousu, Daniele Ghidoli, Simon Jung, Jeffrey Clark
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Publication number: 20180361049Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.Type: ApplicationFiled: June 25, 2018Publication date: December 20, 2018Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
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Patent number: 10034973Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.Type: GrantFiled: July 11, 2016Date of Patent: July 31, 2018Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
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Publication number: 20170232177Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.Type: ApplicationFiled: November 2, 2016Publication date: August 17, 2017Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
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Patent number: 9724154Abstract: Systems and methods are disclosed for providing and using an irrigated ablation catheter. The catheter may include a distal shell electrode having irrigation apertures. An insert disposed within the electrode has protrusions that mate with orifices in the shell of the electrode. Each protrusion has a port communicating with at least one interior lumen in the insert and a sensor is disposed in each port. A support seals the proximal end of the electrode and engages the insert. The plurality of sensors may be used to measure electrical and thermal characteristics surrounding the electrode and may help assess contact between the electrode and tissue and/or determine movement of the electrode during ablation.Type: GrantFiled: November 24, 2014Date of Patent: August 8, 2017Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.Inventors: Jeffrey Schultz, Maria J. Duarte, Daniele Ghidoli, Kelvin Chuu, Meir Bar-Tal, Jeffrey Clark, Avri Hazan, Abraham Berger
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Publication number: 20170007756Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.Type: ApplicationFiled: July 11, 2016Publication date: January 12, 2017Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
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Patent number: 9517296Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.Type: GrantFiled: September 27, 2013Date of Patent: December 13, 2016Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
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Patent number: 9415152Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.Type: GrantFiled: May 30, 2014Date of Patent: August 16, 2016Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
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Publication number: 20160143690Abstract: Systems and methods are disclosed for providing and using an irrigated ablation catheter. The catheter may include a distal shell electrode having irrigation apertures. An insert disposed within the electrode has protrusions that mate with orifices in the shell of the electrode. Each protrusion has a port communicating with at least one interior lumen in the insert and a sensor is disposed in each port. A support seals the proximal end of the electrode and engages the insert. The plurality of sensors may be used to measure electrical and thermal characteristics surrounding the electrode and may help assess contact between the electrode and tissue and/or determine movement of the electrode during ablation.Type: ApplicationFiled: November 24, 2014Publication date: May 26, 2016Inventors: Jeffrey Schultz, Maria J. Duarte, Daniele Ghidoli, Kelvin Chuu, Meir Bar-Tal, Jeffrey Clark, Avri Hazan, Abraham Berger
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Publication number: 20160128765Abstract: Systems and methods are disclosed for providing and using an irrigated ablation catheter. The catheter may include a distal shell electrode having irrigation apertures. A sensor array formed on a flexible substrate conforms to an inner surface of the electrode and an insert disposed within the interior space engages the sensor array to position sensors of the sensor array in desired locations relative to the electrode. A support seals the proximal end of the electrode and engages the insert. The plurality of sensors may be used to measure electrical and thermal characteristics surrounding the electrode and may help assess contact between the electrode and tissue and/or determine movement of the electrode during ablation.Type: ApplicationFiled: November 11, 2014Publication date: May 12, 2016Inventors: Jeffrey Schultz, Kelvin CHUU, Daniele GHIDOLI
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Patent number: 9192393Abstract: A surgical, manually operated, hand-held MRI-compatible drill for drilling though target bone of a patient includes: a housing; a ring gear held in the housing; a hand crank attached to ring gear and the housing; a pinion gear held in the housing in cooperating alignment with the ring gear; an elongate shaft attached to the pinion on one end portion and to a chuck support on an opposing end portion; a chuck attached to the chuck support held; and jaws attached to the chuck support and residing in the chuck adapted to hold a drill bit. The drill is light-weight. The components can all be polymeric.Type: GrantFiled: March 7, 2013Date of Patent: November 24, 2015Assignee: MRI Interventions, Inc.Inventors: Peter Piferi, Daniele Ghidoli
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Patent number: 9192446Abstract: An MRI-guided interventional system for use with a patient and an interventional device includes a base, a trajectory guide frame, and a mounting device. The base is configured to be secured to a body of the patient. The trajectory guide frame includes a targeting cannula. The targeting cannula has an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device. The trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo. A plurality of patient engagement structures are provided on the base and are configured to penetrate tissue of the body and to space the base apart from the tissue. The system further includes a plurality of fasteners configured to secure the base to the body.Type: GrantFiled: March 13, 2013Date of Patent: November 24, 2015Assignee: MRI Interventions, Inc.Inventors: Peter Piferi, Daniele Ghidoli, Rajesh Pandey, Jesse Flores
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Patent number: 9078588Abstract: Intrabody MRI-compatible medical devices with a rigid stylet body with opposing distal and proximal ends with a wall enclosing at least one cavity extending therebetween. The stylet body has first and second laterally spaced apart and opposing external longitudinally extending recessed surfaces and at least one pair of transversely spaced apart apertures extending through the wall and at least one conductor having a length that extends through the cavity then exits the cavity to define at least one external loop extending between the distal end of the stylet body and the pair of transversely spaced apart apertures. First and second legs of each loop snugly abut a respective first and second recessed surface of the stylet body to thereby cooperate with the stylet body to define a substantially cylindrical shape. The at least one conductor with the at least one loop is configured to act as an MRI antenna.Type: GrantFiled: March 8, 2013Date of Patent: July 14, 2015Assignee: MRI Interventions, Inc.Inventors: Daniele Ghidoli, Kamal Vij
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Publication number: 20140339149Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.Type: ApplicationFiled: May 30, 2014Publication date: November 20, 2014Applicant: Fresenius Medical Care Holdings, Inc.Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
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Patent number: 8886288Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.Type: GrantFiled: January 10, 2013Date of Patent: November 11, 2014Assignee: MRI Interventions, Inc.Inventors: Kimble L. Jenkins, Peter Piferi, Kamal Vij, Daniele Ghidoli, Jesse Flores
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Publication number: 20140257086Abstract: Intrabody MRI-compatible medical devices with a rigid stylet body with opposing distal and proximal ends with a wall enclosing at least one cavity extending therebetween. The stylet body has first and second laterally spaced apart and opposing external longitudinally extending recessed surfaces and at least one pair of transversely spaced apart apertures extending through the wall and at least one conductor having a length that extends through the cavity then exits the cavity to define at least one external loop extending between the distal end of the stylet body and the pair of transversely spaced apart apertures. First and second legs of each loop snugly abut a respective first and second recessed surface of the stylet body to thereby cooperate with the stylet body to define a substantially cylindrical shape. The at least one conductor with the at least one loop is configured to act as an MRI antenna.Type: ApplicationFiled: March 8, 2013Publication date: September 11, 2014Inventors: Daniele Ghidoli, Kamal Vij
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Patent number: 8825133Abstract: An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.Type: GrantFiled: January 24, 2013Date of Patent: September 2, 2014Assignee: MRI Interventions, Inc.Inventors: Kimble L. Jenkins, Peter Piferi, Kamal Vij, Daniele Ghidoli, Jesse Flores, Parag V. Karmarkar, Rajesh Pandey
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Patent number: 8771511Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.Type: GrantFiled: January 9, 2012Date of Patent: July 8, 2014Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph