Patents by Inventor Daniele Ghidoli

Daniele Ghidoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170007756
    Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.
    Type: Application
    Filed: July 11, 2016
    Publication date: January 12, 2017
    Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
  • Patent number: 9517296
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: December 13, 2016
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
  • Patent number: 9415152
    Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: August 16, 2016
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
  • Publication number: 20160143690
    Abstract: Systems and methods are disclosed for providing and using an irrigated ablation catheter. The catheter may include a distal shell electrode having irrigation apertures. An insert disposed within the electrode has protrusions that mate with orifices in the shell of the electrode. Each protrusion has a port communicating with at least one interior lumen in the insert and a sensor is disposed in each port. A support seals the proximal end of the electrode and engages the insert. The plurality of sensors may be used to measure electrical and thermal characteristics surrounding the electrode and may help assess contact between the electrode and tissue and/or determine movement of the electrode during ablation.
    Type: Application
    Filed: November 24, 2014
    Publication date: May 26, 2016
    Inventors: Jeffrey Schultz, Maria J. Duarte, Daniele Ghidoli, Kelvin Chuu, Meir Bar-Tal, Jeffrey Clark, Avri Hazan, Abraham Berger
  • Publication number: 20160128765
    Abstract: Systems and methods are disclosed for providing and using an irrigated ablation catheter. The catheter may include a distal shell electrode having irrigation apertures. A sensor array formed on a flexible substrate conforms to an inner surface of the electrode and an insert disposed within the interior space engages the sensor array to position sensors of the sensor array in desired locations relative to the electrode. A support seals the proximal end of the electrode and engages the insert. The plurality of sensors may be used to measure electrical and thermal characteristics surrounding the electrode and may help assess contact between the electrode and tissue and/or determine movement of the electrode during ablation.
    Type: Application
    Filed: November 11, 2014
    Publication date: May 12, 2016
    Inventors: Jeffrey Schultz, Kelvin CHUU, Daniele GHIDOLI
  • Patent number: 9192393
    Abstract: A surgical, manually operated, hand-held MRI-compatible drill for drilling though target bone of a patient includes: a housing; a ring gear held in the housing; a hand crank attached to ring gear and the housing; a pinion gear held in the housing in cooperating alignment with the ring gear; an elongate shaft attached to the pinion on one end portion and to a chuck support on an opposing end portion; a chuck attached to the chuck support held; and jaws attached to the chuck support and residing in the chuck adapted to hold a drill bit. The drill is light-weight. The components can all be polymeric.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: November 24, 2015
    Assignee: MRI Interventions, Inc.
    Inventors: Peter Piferi, Daniele Ghidoli
  • Patent number: 9192446
    Abstract: An MRI-guided interventional system for use with a patient and an interventional device includes a base, a trajectory guide frame, and a mounting device. The base is configured to be secured to a body of the patient. The trajectory guide frame includes a targeting cannula. The targeting cannula has an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device. The trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo. A plurality of patient engagement structures are provided on the base and are configured to penetrate tissue of the body and to space the base apart from the tissue. The system further includes a plurality of fasteners configured to secure the base to the body.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: November 24, 2015
    Assignee: MRI Interventions, Inc.
    Inventors: Peter Piferi, Daniele Ghidoli, Rajesh Pandey, Jesse Flores
  • Patent number: 9078588
    Abstract: Intrabody MRI-compatible medical devices with a rigid stylet body with opposing distal and proximal ends with a wall enclosing at least one cavity extending therebetween. The stylet body has first and second laterally spaced apart and opposing external longitudinally extending recessed surfaces and at least one pair of transversely spaced apart apertures extending through the wall and at least one conductor having a length that extends through the cavity then exits the cavity to define at least one external loop extending between the distal end of the stylet body and the pair of transversely spaced apart apertures. First and second legs of each loop snugly abut a respective first and second recessed surface of the stylet body to thereby cooperate with the stylet body to define a substantially cylindrical shape. The at least one conductor with the at least one loop is configured to act as an MRI antenna.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: July 14, 2015
    Assignee: MRI Interventions, Inc.
    Inventors: Daniele Ghidoli, Kamal Vij
  • Publication number: 20140339149
    Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.
    Type: Application
    Filed: May 30, 2014
    Publication date: November 20, 2014
    Applicant: Fresenius Medical Care Holdings, Inc.
    Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
  • Patent number: 8886288
    Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: November 11, 2014
    Assignee: MRI Interventions, Inc.
    Inventors: Kimble L. Jenkins, Peter Piferi, Kamal Vij, Daniele Ghidoli, Jesse Flores
  • Publication number: 20140257086
    Abstract: Intrabody MRI-compatible medical devices with a rigid stylet body with opposing distal and proximal ends with a wall enclosing at least one cavity extending therebetween. The stylet body has first and second laterally spaced apart and opposing external longitudinally extending recessed surfaces and at least one pair of transversely spaced apart apertures extending through the wall and at least one conductor having a length that extends through the cavity then exits the cavity to define at least one external loop extending between the distal end of the stylet body and the pair of transversely spaced apart apertures. First and second legs of each loop snugly abut a respective first and second recessed surface of the stylet body to thereby cooperate with the stylet body to define a substantially cylindrical shape. The at least one conductor with the at least one loop is configured to act as an MRI antenna.
    Type: Application
    Filed: March 8, 2013
    Publication date: September 11, 2014
    Inventors: Daniele Ghidoli, Kamal Vij
  • Patent number: 8825133
    Abstract: An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: September 2, 2014
    Assignee: MRI Interventions, Inc.
    Inventors: Kimble L. Jenkins, Peter Piferi, Kamal Vij, Daniele Ghidoli, Jesse Flores, Parag V. Karmarkar, Rajesh Pandey
  • Patent number: 8771511
    Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.
    Type: Grant
    Filed: January 9, 2012
    Date of Patent: July 8, 2014
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
  • Publication number: 20140138294
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Application
    Filed: September 27, 2013
    Publication date: May 22, 2014
    Applicant: Fresenius Medical Care Holdings, Inc.
    Inventors: Barry Neil Fulkerson, James Roswell Braig, David J. Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
  • Publication number: 20140066750
    Abstract: An MRI-guided interventional system for use with a patient and an interventional device includes a base, a trajectory guide frame, and a mounting device. The base is configured to be secured to a body of the patient. The trajectory guide frame includes a targeting cannula. The targeting cannula has an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device. The trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo. A plurality of patient engagement structures are provided on the base and are configured to penetrate tissue of the body and to space the base apart from the tissue. The system further includes a plurality of fasteners configured to secure the base to the body.
    Type: Application
    Filed: March 13, 2013
    Publication date: March 6, 2014
    Applicant: MRI Interventions, Inc.
    Inventors: Peter Piferi, Daniele Ghidoli, Rajesh Pandey, Jesse Flores
  • Publication number: 20130325012
    Abstract: A surgical, manually operated, hand-held MRI-compatible drill for drilling though target bone of a patient includes: a housing; a ring gear held in the housing; a hand crank attached to ring gear and the housing; a pinion gear held in the housing in cooperating alignment with the ring gear; an elongate shaft attached to the pinion on one end portion and to a chuck support on an opposing end portion; a chuck attached to the chuck support held; and jaws attached to the chuck support and residing in the chuck adapted to hold a drill bit. The drill is light-weight. The components can all be polymeric.
    Type: Application
    Filed: March 7, 2013
    Publication date: December 5, 2013
    Inventors: Peter Piferi, Daniele Ghidoli
  • Patent number: 8597505
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: December 3, 2013
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Barry Neil Fulkerson, Russell Thomas Joseph, James Roswell Braig, Victor Gura, David J. Mishelevich, Thomas Robinson, Charles Clemens, Milan Trcka, Clark Berg Foster, Daniele Ghidoli, Martin Hering, Frank Isackson, Jan Brian Zwierstra, Mark Forrest Smith
  • Patent number: 8369930
    Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: February 5, 2013
    Assignee: MRI Interventions, Inc.
    Inventors: Kimble L. Jenkins, Peter Piferi, Kamal Vij, Daniele Ghidoli, Jesse Flores
  • Publication number: 20120103885
    Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.
    Type: Application
    Filed: January 9, 2012
    Publication date: May 3, 2012
    Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph
  • Patent number: 8114288
    Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine. Two-way valves in the manifold are used to direct the dialysate flow to the dialyzer in hemodialysis mode of operation and to bypass the dialyzer to direct the flow of infusion grade dialysate directly to the patient in hemofiltration mode of operation.
    Type: Grant
    Filed: November 28, 2008
    Date of Patent: February 14, 2012
    Assignee: Fresenlus Medical Care Holdings, Inc.
    Inventors: Thomas Patrick Robinson, Charles E. Clemens, David Jacob Mishelevich, James Roswell Braig, Barry Neil Fulkerson, Daniele Ghidoli, Russell Thomas Joseph