Abstract: A data communication system for transferring data from a hardware unit to a blockchain or other distributed ledger. The system includes a hardware interface to connect to the hardware unit, and a device having a microcontroller, a secure element connected to the microcontroller, first communication module, and a communication protocol for enabling the microcontroller to communicate with the hardware interface through the first communication module. The microcontroller is configured to: read data from the hardware unit through the hardware interface; generate a transaction corresponding to the data; securely generate a blockchain private key (dB); digitally sign the transaction by a blockchain private key (dB); deliver the signed transaction, and then delete the blockchain private key (dB) from volatile memory of the hardware unit. The microcontroller is adapted to generate a blockchain private key (dB) from parameters contained in part from the device itself and in part from the hardware interface.

Abstract: The present disclosure is directed to a system and a method for acquiring data related to a certain event from a source like a data network gateway or an industrial machine or a set of sensors, extract relevant information from the acquired data, encrypt the information by means of hardware powered security chips and then securely transfer the information to a single or multiple blockchain, or other kind of distributed ledgers, for validation, automatically and without any need of human intervention.

Abstract: Method for defining a code to be executed by programmable control devices comprising: —providing a programming language; —providing a code written in that programming language; —compiling such code in machine language; —transferring said machine language code on a program memory for its execution by the control device, wherein said machine language code is divided into core code and application code, said application code being loaded into the program memory regardless of the core code, without performing a linking operation of the two codes before said transfer. A corresponding system is also disclosed.

Abstract: Method for defining a code to be executed by programmable control devices comprising: —providing a programming language; —providing a code written in that programming language; —compiling such code in machine language; —transferring said machine language code on a program memory for its execution by the control device, wherein said machine language code is divided into core code and application code, said application code being loaded into the program memory regardless of the core code, without performing a linking operation of the two codes before said transfer. A corresponding system is also disclosed.

Abstract: Embodiments of the invention provide a chamber for a bioreactor, the chamber having a fluid inlet aperture and a fluid outlet aperture disposed at respective different locations of a wall of the chamber, with respect to a normal upright orientation of the chamber the chamber being provided with an upper wall portion defining an upper boundary of the chamber. The upper wall portion has an internal surface having a first portion that is vertically displaced with respect to a second portion. The internal surface of the upper wall portion is arranged to promote expulsion of trapped gas bubbles through the outlet aperture, the first and second portions of the upper wall portion each comprising a sloped portion.

Abstract: Embodiments of the invention provide a bioreactor chamber assembly comprising: a bioreactor chamber comprising first and second portions arranged to be coupled to one another thereby to provide a liquid-tight seal therebetween; a pair of clamp members; and a pair of resilient loop elements, wherein the clamp members are arranged to sandwich the chamber between the clamp members and the loop elements are arranged to apply a force between the clamp members to urge the first and second portions together.

Abstract: A bioreactor (1) for subjecting a cell culture (3) to a hydrodynamic pressure stimulus is described. This hydrodynamic pressure is generated inside at least one culture chamber (2) by means of variation of the mean distance, with a controlled speed, of a surface relative to the surface on which the culture (3) is positioned and between which the culture medium (5) is free to flow.

Abstract: Embodiments of the invention provide a bioreactor chamber assembly comprising: a bioreactor chamber comprising first and second portions arranged to be coupled to one another thereby to provide a liquid-tight seal therebetween; a pair of clamp members; and a pair of resilient loop elements, wherein the clamp members are arranged to sandwich the chamber between the clamp members and the loop elements are arranged to apply a force between the clamp members to urge the first and second portions together.

Abstract: Embodiments of the invention provide a chamber for a bioreactor, the chamber having a fluid inlet aperture and a fluid outlet aperture disposed at respective different locations of a wall of the chamber, with respect to a normal upright orientation of the chamber the chamber being provided with an upper wall portion defining an upper boundary of the chamber. The upper wall portion has an internal surface having a first portion that is vertically displaced with respect to a second portion. The internal surface of the upper wall portion is arranged to promote expulsion of trapped gas bubbles through the outlet aperture, the first and second portions of the upper wall portion each comprising a sloped portion.