Patents by Inventor Daniele Nistri

Daniele Nistri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phthalocyanine derivative consisting of a mixture of 4 isomers
    Patent number: 10730890
    Abstract: There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: August 4, 2020
    Assignee: MOLTENI THERAPEUTICS S.R.L.
    Inventors: Gabrio Roncucci, Donata Dei, Giacomo Chiti, Daniele Nistri
  • PHTHALOCYANINE DERIVATIVE CONSISTING OF A MIXTURE OF 4 ISOMERS
    Publication number: 20170073358
    Abstract: There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight.
    Type: Application
    Filed: January 28, 2016
    Publication date: March 16, 2017
    Inventors: Gabrio RONCUCCI, Donata DEI, Giacomo CHITI, Daniele NISTRI
  • NOVEL PHTHALOCYANINE DERIVATIVES FOR THERAPEUTIC USE
    Publication number: 20140163218
    Abstract: There are described phthalocyanine derivates, the pharmaceutical compositions and the medical devices that contain them, possibly in combination with chelating agents, such as EDTA, useful for treating, by means of photodynamic therapy, diseases characterised by cellular hyperproliferation, microbial infections caused by Gram? bacteria, Gram+ bacteria and fungi, and for treating various types of infected and non-infected ulcers.
    Type: Application
    Filed: August 6, 2012
    Publication date: June 12, 2014
    Applicant: MOLTENI THERAPEUTICS S.R.L.
    Inventors: Donata Dei, Gabrio Roncucci, Gianluca Soldaini, Daniele Nistri, Giacomo Chiti, Moira Municchi, Lia Fantetti, Francesco Giuliani
  • Meso-substituted porphyrins
    Patent number: 8288528
    Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitizing agents, in particular in photodynamic therapy, are herein described.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: October 16, 2012
    Assignee: L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
  • Process for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group
    Patent number: 8242262
    Abstract: A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitizing agents in photodynamic therapy.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: August 14, 2012
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'di Esercizio S.p.A.
    Inventors: Donata Dei, Giacomo Chiti, Daniele Nistri, Gabrio Roncucci, Aldo Hendrikus Velders, Salvatore Demartis, Valentina Paschetta
  • PHTHALOCYANINE DERIVATIVE CONSISTING OF A MIXTURE OF 4 ISOMERS
    Publication number: 20120135972
    Abstract: There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight.
    Type: Application
    Filed: July 30, 2010
    Publication date: May 31, 2012
    Inventors: Gabrio Roncucci, Donata Dei, Giacomo Chiti, Daniele Nistri
  • Meso-substituted porphyrins
    Patent number: 7947674
    Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitizing agents, in particular in photodynamic therapy, are herein described.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: May 24, 2011
    Assignee: L. Molteni & C. Dei Fratelli Alitti
    Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
  • MESO-SUBSTITUTED PORPHYRINS
    Publication number: 20110112464
    Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitising agents, in particular in photodynamic therapy, are herein described.
    Type: Application
    Filed: January 14, 2011
    Publication date: May 12, 2011
    Applicant: L. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.P.A.
    Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
  • Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof
    Patent number: 7915248
    Abstract: The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.
    Type: Grant
    Filed: September 10, 2005
    Date of Patent: March 29, 2011
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'Di Esercizio S.p.A
    Inventors: Donata Dei, Gabrio Roncucci, Daniele Nistri, Yann Raoul, Giacomo Chiti, Moira Municchi, Giulio Jori
  • Process for Preparing Chlorides of Phthalocyanine Derivatives Comprising at Least a Quaternary Ammonium Group
    Publication number: 20090131393
    Abstract: A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitising agents in photodynamic therapy.
    Type: Application
    Filed: May 4, 2006
    Publication date: May 21, 2009
    Applicant: L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A.
    Inventors: Donata Dei, Giacomo Chiti, Daniele Nistri, Gabrio Roncucci, Aldo Hendrikus Velders, Salvatore Demartis, Valentina Paschetta
  • Boronated Metal-Phthalocyanines, Process For Their Preparation, Pharmaceutical Compositions Comprising Them And Use Thereof
    Publication number: 20080004239
    Abstract: The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.
    Type: Application
    Filed: September 10, 2005
    Publication date: January 3, 2008
    Inventors: Donata Dei, Gabrio Roncucci, Daniele Nistri, Yann Raoul, Giacomo Chiti, Moira Municchi, Giulio Jori
  • Metal substituted non-centrosimmetrical phthalocyanine analogues, their preparation and use in photodynamic therapy and in vivo diagnostic
    Patent number: 7153841
    Abstract: Phthalocyanine analogues having an active group able to link the phthalocyanine t carriers molecules and phthalocyanine to carriers molecules and phthalocyanine analogues as phthalocyanine-carrier conjugates showing enhanced photodynamic properties, red shifted absorption characteristic, all useful for photodynamic therapy, are described. Photosensitizers themselves or the photosensitizers-carriers conjugates are useful compounds either for treatment of various infectious diseases, the in vivo eradication of micro-organisms as well as diseases characterized by cellular hyperproliferation, in particular tumours psoriasis, actinic keratosis, atheromas, endoarterial hyperplasia and prostate hyperplasia. The above compounds can be also useful for blood and blood derivatives sterilization and in vivo/vitro diagnostics.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: December 26, 2006
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Donata Dei, Maria Paola De Filippis, Lia Fantetti, Daniele Nistri
  • Meso-substituted porphyrins
    Publication number: 20060040914
    Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitising agents, in particular in photodynamnic therapy, are herein described.
    Type: Application
    Filed: October 21, 2003
    Publication date: February 23, 2006
    Applicant: L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A.
    Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
  • Metal substituted non centrosimmetrical phthalocyanine analogues, their preparation and use in photodynamic theraphy and in vivo diagnostic
    Publication number: 20040156787
    Abstract: Phthalocyanine analogues having an active able to link the phthalocyanine t carriers molecules and phthalocyanine analogues as phthalocyanine-carrier conjugates showing enhanced photodynamic properties, red shifted absorption characteristic, all useful for photodynamic therapy, are described. Photosensitizers themselves or the photosensitizers-carriers conjugates are useful compounds either for treatment of various infectious diseases, the in vivo eradication of micro-organisms as well as diseases characterized by cellular hyperproliferation, in particular tumours psoriasis, actinic keratosis, atheromas, endoarterial hyperplasia and prostate hyperplasia. The above compounds can be also useful for blood and blood derivatives sterilization and in vivo/vitro diagnostics.
    Type: Application
    Filed: April 1, 2004
    Publication date: August 12, 2004
    Inventors: Gabrio Roncucci, Donata Dei, Maria Paola De Filippis, Lia Fantetti, Daniele Nistri